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Researchers discover new evidence on how cholesterol transfers from HDLs to LDLs

Researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) have found new evidence to explain how cholesteryl ester transfer protein (CETP) mediates the transfer of cholesterol from "good" high density lipoproteins (HDLs) to "bad" low density lipoproteins.

21 Feb 2012

University of Pennsylvania, IMUC enter license agreement for dendritic-cell production method

ImmunoCellular Therapeutics today announced that it has entered into an agreement with the University of Pennsylvania under which University of Pennsylvania has granted the Company an exclusive, worldwide license for a patent pending technology for the production of high-activity dendritic cells.

21 Feb 2012

DPN similar in prediabetic patients and healthy people

In a reversal of two decades of medical reports, a Mayo Clinic study finds the frequency of nerve damage called diabetic polyneuropathy is similar in prediabetic patients and healthy people. Physicians should seek explanations other than prediabetes for patients who have painful small fiber polyneuropathy, the researchers say.

21 Feb 2012

FDA grants orphan-drug designation to Arno's AR-42 for treatment of meningioma, schwannoma

Arno Therapeutics, Inc. announced today that its investigational compound, AR-42, has been granted orphan-drug designation by the U.S. Food and Drug Administration for the treatment of meningioma and schwannoma of the central nervous system.

21 Feb 2012

FDA grants Priority Review for Repligen's SecreFlo NDA

Repligen Corporation announced today that the U.S. Food and Drug Administration (FDA) has accepted for filing and granted Priority Review to the Company's new drug application (NDA) for SecreFlo for the improved detection of pancreatic duct abnormalities in patients with pancreatitis.

21 Feb 2012

Genomic instability allows malignant cells to acquire more deadly characteristics

Genomic instability caused by an erosion of the protective caps on chromosomes, followed by activation of an enzyme that reinforces those aps, allows malignant cells to evade destruction and acquire more deadly characteristics, researchers report in an Online Now article at the journal Cell.

21 Feb 2012

Telomerase reactivation in malignant cells after genomic instability causes cancer progression

Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive and spread, scientists report in the Feb. 17 issue of Cell.

21 Feb 2012

Gene that destroys cancerous cells also causes ageing

The role of one of our genes which protects us from cancer but could also cause us to age will be explained in a lecture at the University of Leicester.

21 Feb 2012

New triple-therapies found cost-effective for chronic hepatitis C patients with advanced liver disease

A towering $60,000 bill, a year of fierce, flu-like symptoms and a running risk of depression are among the possible costs of two new hepatitis C treatments. But according to Stanford University health policy researchers, they might be worth it.

21 Feb 2012

Study finds increase in social smoking among young adults

Extending the smoking ban outside bars could help curb "social smoking" because this goes hand in hand with drinking, suggests a small qualitative study published online in Tobacco Control.

21 Feb 2012

Infant colic may be an early sign of migraine headache later in life

New research suggests that mothers who experience migraine may be more likely to have a baby with colic than mothers without a history of migraine. Colic is defined as excessive crying in an otherwise healthy infant. The research was released today and will be presented at the American Academy of Neurology's 64th Annual Meeting in New Orleans April 21 to April 28, 2012.

21 Feb 2012

Frailty test for elderly also helps measure transplant candidates

A simple, 10-minute bedside assessment conducted prior to surgery appears to be the best method yet for predicting which kidney transplant patients will do well with their new organs, new Johns Hopkins research suggests.

21 Feb 2012

Sitting for long hours affects hips, spine, shoulders and the heart

You may feel productive putting in long days at the office. But while your mind is active, your body isn't. There is a growing body of research that supports the idea that, regardless of your exercise routine after hours, the more time you spend sitting each day, the higher your risk of heart disease. Evidence suggests your hips, spine and shoulders suffer as well.

21 Feb 2012

Intraoperative monitoring of spinal cord may help prevent paralysis

The American Academy of Neurology is issuing an updated guideline that recommends monitoring the spinal cord during spinal surgery and certain chest surgeries to help prevent paralysis, or loss of muscle function, related to the surgeries.

21 Feb 2012

Movies featuring alcohol induce teens to start drinking

Young teens who watch a lot of movies featuring alcohol are twice as likely to start drinking compared to peers who watch relatively few such films, reveals research published in the online journal BMJ Open.

21 Feb 2012

The final link in world's longest living-donor kidney transplant chain

A Loyola University Medical Center patient has become the final link in the world's longest living-donor kidney transplant chain.

20 Feb 2012

ReCor Medical's PARADISE ultrasound platform for achieving renal denervation receives CE mark

ReCor Medical, an emerging medical device company, announced today that its PARADISE (Percutaneous Renal Denervation System) ultrasound platform for achieving renal denervation has received the CE mark. PARADISE is designed to treat patients with 'resistant' hypertension, a major risk factor for cardiovascular disease.

20 Feb 2012

Screening events to find out risk for heart attack or stroke

If you could find out if you had an increased risk of heart attack or stroke, wouldn't you want to know? Even if you are fit and healthy, coronary artery disease (CAD) or peripheral artery disease (PAD) are conditions with little to no symptoms and can put you at an increased risk of heart attack or stroke.

20 Feb 2012

Open application marketplace for ambient assisted-living solutions

The success of Apple's App Store and the Android Market has inspired EU-funded developers of 'Ambient assisted-living' (AAL) solutions to develop their own open application marketplace and work together on interoperable platforms. In doing so, they are hoping to mainstream technology that will help older people live more active and comfortable lives.

20 Feb 2012

James E. Cary Cancer Center to implement RayStation treatment planning system

RaySearch Laboratories AB has received an order for its RayStation treatment planning system from the James E. Cary Cancer Center located in Hannibal, Missouri.

20 Feb 2012