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New model developed to predict atrial fibrillation stroke risk factors

A more accurate and reliable stroke prediction model has been developed to help physicians decide whether to start blood-thinning treatment for patients with atrial fibrillation, as described in the current online issue of the Journal of the American Heart Association.

21 Jun 2013

Researchers receive NIH grant to study key proteins linked to cancer and diabetes

Researchers from the Polytechnic Institute of New York University and NYU have received a grant from the National Institutes of Health (NIH) to further a novel approach to understanding the genetic underpinnings of diseases including cancer and diabetes.

21 Jun 2013

Researchers discover key role of RAP1 gene in obesity

The discovery of an unexpected function for a gene that was associated to another process in the organism might be a solution in search of a problem, a clue to unsuspected connections. That is what has happened with RAP1, a gene that protects telomeres- the ends of chromosomes-after researchers from the Spanish National Cancer Research Centre surprisingly discovered its key role in obesity.

21 Jun 2013

Targeting particular signaling pathway can help prevent temporal lobe epilepsy, scientists report

Temporal lobe epilepsy, the most common form of epilepsy, is characterized by recurrent seizures throughout life and often behavioral abnormalities, with devastating impacts on patients and their families. Unfortunately, the condition is often not responsive to anticonvulsants. Now scientists report online June 20 in the Cell Press journal Neuron that targeting a particular signaling pathway in mice can prevent the development of temporal lobe epilepsy with just two weeks of treatment, offering hope that researchers will be able to develop effective drugs to mitigate recurrent seizures and the development of epilepsy.

21 Jun 2013

Laughing gas is associated with increased risk for perioperative cardiac events

A clinical trial published in the July issue of Anesthesiology may shed some light on whether nitrous oxide ("laughing gas") causes an increased risk for cardiac events, including heart attacks after surgery, particularly among high-risk patients.

20 Jun 2013

BerGenBio AS starts Phase 1 Clinical Trial for BGB324 oral AXL inhibitor

BerGenBio AS today announced the start of a Phase 1 Clinical Trial for BGB324, a first-in-class small molecule inhibitor of AXL tyrosine kinase. BGB324 is a highly selective, oral AXL inhibitor that blocks the epithelial-mesenchymal transition (EMT), which is a key driver of metastasis (cancer spread) and drug-resistance. The Phase 1 clinical trial of BGB324 is a single ascending dose study designed to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of BGB324.

20 Jun 2013

Certain factors and behaviors influence sexual hookups among first-year college women

Casual, no-strings sexual encounters are increasingly common on college campuses, but are some students more likely than others to "hook up"? A new study by researchers with The Miriam Hospital's Centers for Behavioral and Preventive Medicine, published online by the Archives of Sexual Behavior, suggests there are certain factors and behaviors associated with sexual hookups, particularly among first-year college women.

20 Jun 2013

Researchers monitor dynamic cellular events that take place during cardiac regeneration in zebrafish

In a study published in the June 19 online edition of the journal Nature, a scientific team led by researchers from the University of California, San Diego School of Medicine visually monitored the dynamic cellular events that take place when cardiac regeneration occurs in zebrafish after cardiac ventricular injury. Their findings provide evidence that various cell lines in the heart are more plastic, or capable of transformation into new cell types, than previously thought.

20 Jun 2013

Trees are effective tool in reducing air pollution and creating healthier urban environments

In the first effort to estimate the overall impact of a city's urban forest on concentrations of fine particulate pollution (particulate matter less than 2.5 microns, or PM2.5), a U.S. Forest Service and Davey Institute study found that urban trees and forests are saving an average of one life every year per city. In New York City, trees save an average of eight lives every year.

20 Jun 2013

Study reports increasing number of pedestrian injuries caused by cell phone use

More than 1,500 pedestrians were estimated to be treated in emergency rooms in 2010 for injuries related to using a cell phone while walking, according to a new nationwide study.

20 Jun 2013

Genetic process that promotes cervical cancer warns about anti-viral therapies in certain cases

A new understanding of the genetic process that can lead to cervical cancer may help improve diagnosis of potentially dangerous lesions for some women, and also raises a warning flag about the use of anti-viral therapies in certain cases - suggesting they could actually trigger the cancer they are trying to cure.

20 Jun 2013

Nearly 70% of Americans use at least one prescription drug, say researchers

Nearly 70 percent of Americans are on at least one prescription drug, and more than half take two, Mayo Clinic researchers say. Antibiotics, antidepressants and painkilling opioids are most commonly prescribed, their study found. Twenty percent of patients are on five or more prescription medications, according to the findings, published online in the journal Mayo Clinic Proceedings.

20 Jun 2013

Research: Stroke patients may be more likely to develop problems with memory and thinking

People who experience any stroke symptoms—but do not have a stroke—may also be more likely to develop problems with memory and thinking, according to new research published in the June 19, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology.

20 Jun 2013

Chemical hormone released due to stress can trigger mechanism for late onset of Alzheimer's disease

A chemical hormone released in the body as a reaction to stress could be a key trigger of the mechanism for the late onset of Alzheimer's disease, according to a study by researchers at Temple University.

20 Jun 2013

NUS researchers develop highly realistic 3-D tumor model to track progress of drug therapy

A team of NUS researchers from the Departments of Bioengineering and Orthopaedic Surgery has developed a highly realistic three-dimensional (3-D) tumour model. As it replicates the conditions in the body, it is able to track the effectiveness and progress of drug therapy.

20 Jun 2013

Sports concussions and repeated hits to head may cause chronic traumatic encephalopathy

It's been widely reported in the media that sports concussions and repeated hits to the head cause a progressive brain disease called chronic traumatic encephalopathy (CTE).

20 Jun 2013

CLOTS 3 trial demonstrates efficacy of Covidien's Kendall SCD system on immobile stroke patients

Covidien (NYSE: COV), a leading global provider of healthcare products, today announced that an independent study conducted by the University of Edinburgh has successfully demonstrated the effectiveness of Covidien's Kendall SCD™ system with Vascular Refill Detection Technology on immobile stroke patients.

20 Jun 2013

Researchers launch clinical trial on stem cells to prevent amputations in end stage PAD

University Hospitals Case Medical Center clinical researchers have launched an innovative clinical trial, unique in its design, which will evaluate the ability of a patient's own stem cells to prevent leg amputations in end stage peripheral arterial disease (PAD).

20 Jun 2013

Penn researchers find ALS disease progresses in a stepwise, sequential pattern

The motor neuron disease Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease, progresses in a stepwise, sequential pattern which can be classified into four distinct stages, report pathologists with the Perelman School of Medicine at the University of Pennsylvania in the Annals of Neurology.

20 Jun 2013

Research shows interaction of tau and amyloid-beta in brain may increase progression of AD

For years, Alzheimer's researchers have focused on two proteins that accumulate in the brains of people with Alzheimer's and may contribute to the disease: plaques made up of the protein amyloid-beta, and tangles of another protein, called tau.

20 Jun 2013

Medical Condition News

New model developed to predict atrial fibrillation stroke risk factors

Researchers receive NIH grant to study key proteins linked to cancer and diabetes

Researchers discover key role of RAP1 gene in obesity

Targeting particular signaling pathway can help prevent temporal lobe epilepsy, scientists report

Laughing gas is associated with increased risk for perioperative cardiac events

BerGenBio AS starts Phase 1 Clinical Trial for BGB324 oral AXL inhibitor

Certain factors and behaviors influence sexual hookups among first-year college women

Researchers monitor dynamic cellular events that take place during cardiac regeneration in zebrafish

Trees are effective tool in reducing air pollution and creating healthier urban environments

Study reports increasing number of pedestrian injuries caused by cell phone use

Genetic process that promotes cervical cancer warns about anti-viral therapies in certain cases

Nearly 70% of Americans use at least one prescription drug, say researchers

Research: Stroke patients may be more likely to develop problems with memory and thinking

Chemical hormone released due to stress can trigger mechanism for late onset of Alzheimer's disease

NUS researchers develop highly realistic 3-D tumor model to track progress of drug therapy

Sports concussions and repeated hits to head may cause chronic traumatic encephalopathy

CLOTS 3 trial demonstrates efficacy of Covidien's Kendall SCD system on immobile stroke patients

Researchers launch clinical trial on stem cells to prevent amputations in end stage PAD

Penn researchers find ALS disease progresses in a stepwise, sequential pattern

Research shows interaction of tau and amyloid-beta in brain may increase progression of AD

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

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