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Older patients with head and neck cancers less likely to die in high-volume hospitals

A study of older patients with advanced head and neck cancers has found that where they were treated significantly influenced their survival.

4 Mar 2013

Study identifies how new ALS gene mutations cause other diseases of the brain, muscle and bone

Researchers supported by The ALS Association have discovered how mutations in new amyotrophic lateral sclerosis (ALS) genes cause not only ALS but also other diseases of the brain, muscle and bone.

4 Mar 2013

Poll shows compelling association between exercise and better sleep

Exercise can affect your sleep. The results of the National Sleep Foundation's 2013 Sleep in America poll show a compelling association between exercise and better sleep.

4 Mar 2013

Study instructs how to design new, more powerful vaccine formulas for cancer

Cancer vaccines that attempt to stimulate an immune system assault fail because the killer T cells aimed at tumors instead find the vaccination site a more inviting target, scientists at The University of Texas MD Anderson Cancer Center report in Nature Medicine.

4 Mar 2013

Investigators identify seven new genetic regions associated with AMD

An international group of investigators has identified seven new genetic regions associated with age-related macular degeneration (AMD), a common cause of blindness in older individuals. The findings, reported online March 3 in Nature Genetics, could point to new biological pathways and therapeutic targets for AMD.

4 Mar 2013

Researchers discover how LRRK2 mutations in familial Parkinson's damage brain cells

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the most common genetic mutations in familial Parkinson's disease damage brain cells.

4 Mar 2013

Study identifies two gene mutations that lead to death of nerve cells in ALS

A study led by St. Jude Children's Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and related degenerative diseases.

4 Mar 2013

Regeneron, Sanofi announce pooled data from Phase 1b trials with dupilumab for atopic dermatitis

Sanofi and Regeneron Pharmaceuticals, Inc. announced that pooled data from two Phase 1b trials with dupilumab (REGN668/SAR231893), an investigational, high-affinity, subcutaneously administered, fully-human antibody targeting the alpha subunit of the interleukin 4 receptor (IL-4R alpha), were presented at the 71st Annual Meeting of the American Academy of Dermatology (AAD) in Miami.

4 Mar 2013

Shortage of TDP-43 protein causes muscle wasting and stunted nerve cells

A shortage of a protein called TDP-43 caused muscle wasting and stunted nerve cells. This finding supports the idea that malfunction of this protein plays a decisive role in ALS and FTD. The study is published in the "Proceedings of the National Academy of Sciences of the USA" (PNAS).

3 Mar 2013

Pregnancy-related foot changes may contribute to women's increased risk for arthritis

A new University of Iowa study confirms what many women have long suspected - that pregnancy permanently changes the size and shape of a woman's feet.

3 Mar 2013

D.C., N.Y. hospitals consider new team-ups, merger

Health systems and hospitals in Washington and New York City are joining forces: In Washington, health systems are forming a bond they say will improve pediatric care. In New York, a merger of hospitals is proposed.

3 Mar 2013

UNC1215 chemical probe can help investigate L3MBTL3 methyl-lysine reader domain

In an article published as the cover story of the March 2013 issue of Nature Chemical Biology, Lindsey James, PhD, research assistant professor in the lab of Stephen Frye, Fred Eshelman Distinguished Professor in the UNC School of Pharmacy and member of the UNC Lineberger Comprehensive Cancer Center, announced the discovery of a chemical probe that can be used to investigate the L3MBTL3 methyl-lysine reader domain.

3 Mar 2013

Researchers identify mechanisms that connect variety of diseases linked with inflammation

A study led by researchers at Boston University School of Medicine (BUSM) has identified epigenetic mechanisms that connect a variety of diseases associated with inflammation.

3 Mar 2013

Colonoscopy is also safe, confirms German Cancer Research Center study

Colon cancer develops slowly. Precancerous lesions usually need many years to turn into a dangerous carcinoma. They are well detectable in an endoscopic examination of the colon called colonoscopy and can be removed during the same examination. Therefore, regular screening can prevent colon cancer much better than other types of cancer.

3 Mar 2013

Global inhibition of all Notch signals would not be safe after bone marrow transplantation

Bone marrow transplant is a key treatment for patients with leukemia, lymphoma, multiple myeloma and other blood disorders. University of Michigan researchers have discovered that inhibiting a signaling pathway in some of the transplanted cells could prevent the most serious potential complications of the procedure, a conflict between the transplanted cells and the recipient's own tissue called graft-versus-host disease.

2 Mar 2013

Melanoma tumours deliberately create conditions that knock out body's premier immune defence

New research in the Journal of Clinical Investigation reveals that tumours in melanoma patients deliberately create conditions that knock out the body's 'premier' immune defence and instead attract a weaker immune response unable to kill off the tumour's cancerous cells.

2 Mar 2013

Oxford researcher wins 2013 John Dystel Prize from AAN, National Multiple Sclerosis Society

The American Academy of Neurology and the National Multiple Sclerosis Society are awarding the 2013 John Dystel Prize for MS Research to George C. Ebers, MD, a leading researcher with the University of Oxford and Oxford University Hospitals Trust in Oxford, United Kingdom.

2 Mar 2013

Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is disease in which the immune system mistakenly attacks healthy tissues, resulting in inflammation and tissue damage. Current treatments are focused on suppression of the immune system, but these therapies can leave patients vulnerable to infection.

2 Mar 2013

Health law implementation likely to proceed - despite sequester's cuts to other health programs

Meanwhile, news outlets report on how the health law is "reshaping" the health care marketplace and how the measure's medical device tax continues to be a point of contention.

2 Mar 2013

NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth

Myocardial hypertrophy, a thickening of the heart muscle, is an adaptation that occurs with increased stress on the heart, such as high blood pressure. As the heart muscle expands, it also requires greater blood flow to maintain access to oxygen and nutrients, necessitating an expansion of the cardiac vasculature.

2 Mar 2013

Medical Condition News

Older patients with head and neck cancers less likely to die in high-volume hospitals

Study identifies how new ALS gene mutations cause other diseases of the brain, muscle and bone

Poll shows compelling association between exercise and better sleep

Study instructs how to design new, more powerful vaccine formulas for cancer

Investigators identify seven new genetic regions associated with AMD

Researchers discover how LRRK2 mutations in familial Parkinson's damage brain cells

Study identifies two gene mutations that lead to death of nerve cells in ALS

Regeneron, Sanofi announce pooled data from Phase 1b trials with dupilumab for atopic dermatitis

Shortage of TDP-43 protein causes muscle wasting and stunted nerve cells

Pregnancy-related foot changes may contribute to women's increased risk for arthritis

D.C., N.Y. hospitals consider new team-ups, merger

UNC1215 chemical probe can help investigate L3MBTL3 methyl-lysine reader domain

Researchers identify mechanisms that connect variety of diseases linked with inflammation

Colonoscopy is also safe, confirms German Cancer Research Center study

Global inhibition of all Notch signals would not be safe after bone marrow transplantation

Melanoma tumours deliberately create conditions that knock out body's premier immune defence

Oxford researcher wins 2013 John Dystel Prize from AAN, National Multiple Sclerosis Society

Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus

Health law implementation likely to proceed - despite sequester's cuts to other health programs

NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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