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Renowned biotech researcher to receive TJU's Lennox K. Black International Prize

Thomas Jefferson University will honor the renowned biotech researcher whose discoveries led to a slew of innovative drugs that revolutionized treatment including Herceptin-one of the first gene-based medications for breast cancer-with its prestigious Lennox K. Black International Prize for Excellence in Biomedical Research.

27 Nov 2012

Low folate and vitamin B12 intake increase risk of melancholic depressive symptoms

A low intake of folate and vitamin B12 increases the risk of melancholic depressive symptoms, according to a study among nearly 3,000 middle-aged and elderly Finnish subjects. On the other hand, non-melancholic depressive symptoms are associated with an increased risk for the metabolic syndrome.

27 Nov 2012

EC approves Regeneron’s EYLEA for treatment of wet AMD

Regeneron Pharmaceuticals, Inc. today announced that EYLEA (aflibercept) Injection has been approved by the European Commission for the treatment of patients with neovascular (wet) age-related macular degeneration (wet AMD).

27 Nov 2012

Chemotherapy can induce brain changes that may affect concentration and memory

Chemotherapy can induce changes in the brain that may affect concentration and memory, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

27 Nov 2012

Leading urologic oncologist explains bladder cancer basics

An unhappy bladder won't be ignored. Frequent urination, pain while urinating, burning while urinating, blood in the urine, and even back pain or pelvic pain can all be symptoms of bladder cancer or other urinary tract problems. The trick, however, is that the absence of urinary symptoms doesn't guarantee a healthy bladder.

27 Nov 2012

Radiologists identify pattern of injuries that may be indicative of elder abuse

Radiologists in Toronto have begun to identify a pattern of injuries that may be indicative of elder abuse, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

27 Nov 2012

First U.S. breathing lung transplant performed in Ronald Reagan UCLA Medical Center

First there was the "heart in a box," a revolutionary experimental technology that allows donor hearts to be delivered to transplant recipients warm and beating rather than frozen in an ice cooler. Now that same technology is being used to deliver "breathing lungs."

27 Nov 2012

Johns Hopkins receives $1.9M NIH grant to establish new center for sleep research

More than one-quarter of the adult population of the U.S. suffers from sleep disturbances known to contribute to life-threatening illnesses such as cardiovascular disease, diabetes, and dementia as well as depression, chronic pain, and fatigue. Often such sleeplessness is a consequence of obesity, lifestyle, and work.

27 Nov 2012

New combinations of medical imaging technologies hold promise for personalized medicine

New combinations of medical imaging technologies hold promise for improved early disease screening, cancer staging, therapeutic assessment, and other aspects of personalized medicine, according to Ge Wang, director of Virginia Tech's Center for Biomedical Imaging, in a recent paper that appeared in the refereed journal PLoS One.

27 Nov 2012

New report analyzes annual trends for biomarker FDA approvals since 2008

"Approval Trends for Biomarker-Based IVD Tests: Realizing the Promise of Personalized Medicine," a new report published by Amplion Research analyzes annual trends for FDA approvals since 2008 with some interesting findings.

27 Nov 2012

Study compares effects of weight loss induced by gastric bypass and banding on metabolic response

Obesity is associated with insulin resistance and type 2 diabetes, both of which can be significantly improved by weight loss. Gastric bypass and adjustable gastric banding are two bariatric surgery techniques that are frequently used to effect weight loss in obese patients, but it is unclear if the two procedures produce different outcomes.

27 Nov 2012

Antifibrinolytics inhibit glycine receptor activity in the brain and cause seizures

Antifibrinolytic drugs are frequently used to prevent blood loss during surgery, but sometimes cause convulsive seizures. In this issue of the Journal of Clinical Investigation, researchers led by Beverly Orser at the University of Toronto investigated the molecular mechanisms that underlie this side effect.

27 Nov 2012

Paper illuminates importance of PKM2 in cancer development and progression

Researchers at The University of Texas MD Anderson Cancer Center have tracked down a cancer-promoting protein's pathway into the cell nucleus and discovered how, once there, it fires up a glucose metabolism pathway on which brain tumors thrive.

26 Nov 2012

CLCA1 molecule plays a special role in the mucus pathway

Respiratory conditions that restrict breathing such as asthma and chronic obstructive pulmonary disease (COPD) are common killers worldwide. But no effective treatments exist to address the major cause of death in these conditions - excess mucus production.

26 Nov 2012

Epilepsy & Behavior Case Reports from Elsevier

Elsevier, a world-leading provider of scientific, technical and medical information products and services, announces the launch of Epilepsy & Behavior Case Reports a new, online-only, Open Access journal devoted to the rapid publication of case reports on the behavioral aspects of seizures and epilepsy.

26 Nov 2012

Researchers discover LSD-1 enzyme as important target for treatment of Ewing sarcoma

Discovery of a new drug with high potential to treat Ewing sarcoma, an often deadly cancer of children and young adults, and the previously unknown mechanism behind it, come hand-in-hand in a new study by researchers from Huntsman Cancer Institute (HCI) at the University of Utah. The report appears in today's online issue of the journal Oncogene.

26 Nov 2012

Word-training program found to restore key words in some dementia patients

A simple word-training program has been found to restore key words in people with a type of dementia that attacks language and our memory for words.

26 Nov 2012

Chronic suppurative lung disease: an interview with Dr Robyn Marsh

Chronic suppurative lung disease, or CSLD, is used to describe a range of lung diseases characterised by a chronic wet cough and progressive lung damage. We are interested in the non-cystic fibrosis forms of the disease with a focus on bronchiectasis – the severe form of CSLD.

26 Nov 2012

Researchers discover molecular basis for potential cancer preventive effects of vitamin D

A team of researchers at McGill University have discovered a molecular basis for the potential cancer preventive effects of vitamin D. The team, led by McGill professors John White and David Goltzman, of the Faculty of Medicine's Department of Physiology, discovered that the active form of vitamin D acts by several mechanisms to inhibit both the production and function of the protein cMYC.

26 Nov 2012

New therapeutic technique to repair and rebuild muscle for degenerative muscle disorders

A study published today in BioMed Central's open access journal Skeletal Muscle reports of a new therapeutic technique to repair and rebuild muscle for sufferers of degenerative muscle disorders. The therapy brings together two existing techniques for muscle repair - cell transplantation and tissue engineering - specifically, mesoangioblast stem cells delivered via a hydrogel cell-carrier matrix.

26 Nov 2012

Medical Condition News

Renowned biotech researcher to receive TJU's Lennox K. Black International Prize

Low folate and vitamin B12 intake increase risk of melancholic depressive symptoms

EC approves Regeneron’s EYLEA for treatment of wet AMD

Chemotherapy can induce brain changes that may affect concentration and memory

Leading urologic oncologist explains bladder cancer basics

Radiologists identify pattern of injuries that may be indicative of elder abuse

First U.S. breathing lung transplant performed in Ronald Reagan UCLA Medical Center

Johns Hopkins receives $1.9M NIH grant to establish new center for sleep research

New combinations of medical imaging technologies hold promise for personalized medicine

New report analyzes annual trends for biomarker FDA approvals since 2008

Study compares effects of weight loss induced by gastric bypass and banding on metabolic response

Antifibrinolytics inhibit glycine receptor activity in the brain and cause seizures

Paper illuminates importance of PKM2 in cancer development and progression

CLCA1 molecule plays a special role in the mucus pathway

Epilepsy & Behavior Case Reports from Elsevier

Researchers discover LSD-1 enzyme as important target for treatment of Ewing sarcoma

Word-training program found to restore key words in some dementia patients

Chronic suppurative lung disease: an interview with Dr Robyn Marsh

Researchers discover molecular basis for potential cancer preventive effects of vitamin D

New therapeutic technique to repair and rebuild muscle for degenerative muscle disorders

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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