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French National Center for Scientific Research scientist wins American Epilepsy Society award

Richard Miles, Ph.D., Research Director, French National Center for Scientific Research, and Group Leader, Cortex and Epilepsy, Institute for the Brain and Spinal Cord, Centre Hospitalier Universtaire Pitie-Salpetriere, Paris, has been named recipient of the prestigious 2012 Epilepsy Research Recognition Award for Basic Science conferred by the American Epilepsy Society (AES).

28 Nov 2012

Researchers discover alternative mechanism for Ras protein activation

The protein Ras plays an important role in cellular growth control. Researchers have focused on the protein because mutations in its gene are found in more than 30 percent of all cancers, making it the most prevalent human oncogene.

28 Nov 2012

Bayer completes recruitment of first cohort for BAY 86-6150 Phase II/III study in hemophilia

Bayer's BAY 86-6150 is being investigated in a Phase II/III study called TRUST (TReatment with Unique recombinant rFVIIa STudy), and the recruitment of the first cohort is now complete.

28 Nov 2012

Yoga appears to be effective treatment for neck pain

According to published estimates, some 20 percent of the population suffers from chronic neck pain caused by a variety of structural dysfunctions in the neck, resulting in impaired quality of life and lost work time. A German study published in The Journal of Pain showed that yoga appears to be an effective treatment for neck pain and provides added benefits of improved psychological well being and quality of life.

28 Nov 2012

Florbetapir PET scans can detect brain amyloid deposits associated with Alzheimer’s

A test to detect brain amyloid deposits associated with Alzheimer disease (AD) provides doctors with useful information on treatment and further testing for patients with cognitive impairment, according to a study published online by the journal Alzheimer Disease & Associated Disorders.

28 Nov 2012

Prevalence of mental health diagnoses increases with long duration of opioid use

Most patients taking opioids for low back pain or other pain syndromes are prescribed low-to moderate doses, but a substantial number are given higher doses. Although there is no consensus on an absolute limit because tolerance varies over time among individual patients, what is known, however, is higher does are associated with elevated risks for side effects, addiction, overdoses and death.

28 Nov 2012

Off label atypical antipsychotic use lacks safety and effectiveness in patients over 40

In older adults, antipsychotic drugs are commonly prescribed off-label for a number of disorders outside of their Food and Drug Administration (FDA)-approved indications - schizophrenia and bipolar disorder. The largest number of antipsychotic prescriptions in older adults is for behavioral disturbances associated with dementia, some of which carry FDA warnings on prescription information for these drugs.

28 Nov 2012

The Neuro clinician-scientists to further research on HIV/AIDS, Parkinson's

Clinician-scientists take a unique, integrated approach that is essential to advancing science and medicine. Problems encountered in the clinic inspire research and new findings from the labs are directly applied to patients' needs.

28 Nov 2012

Digoxin increases risk of death in patients with atrial fibrillation

Digoxin, a drug widely used to treat heart disease, increases the possibility of death when used by patients with a common heart rhythm problem − atrial fibrillation (AF), according to new study findings by University of Kentucky researchers. The results have been published in the prestigious European Heart Journal, and raises serious concerns about the expansive use of this long-standing heart medication in patients with AF.

28 Nov 2012

Study broadens understanding of how cells regulate X chromosome inactivation

In a paper published in the Nov. 21 issue of Cell, a team led by Mauro Calabrese, a postdoctoral fellow at the University of North Carolina in the lab of Terry Magnuson, chair of the department of genetics and member of the UNC Lineberger Comprehensive Cancer Center, broadens the understanding of how cells regulate silencing of the X chromosome in a process known as X-inactivation.

28 Nov 2012

Researchers aim to improve feeling of 'walking on marbles' for arthritis patients

Researchers at the University of Southampton are to undertake a new stage of a study aimed at improving the health and mobility of those suffering from the common complaint of 'walking on marbles' associated with Rheumatoid Arthritis (RA) in the feet.

28 Nov 2012

Patients with RA more likely to have dislocation following hip replacement surgery

In the first systemic review of evidence assessing complications following total joint arthroplasty, patients with rheumatoid arthritis (RA) were found to have an increased risk for hip dislocation after hip replacement surgery compared to those with osteoarthritis (OA). Study findings published online in Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR), also indicate that RA patients have a higher infection risk following total knee replacement than patients with OA.

28 Nov 2012

Cry acoustics may help identify infants at risk of autism

Autism is a poorly understood family of related conditions. People with autism generally lack normal social interaction skills and engage in a variety of unusual and often characteristic behaviors, such as repetitive movements. While there is no specific medical treatment for autism, some success has been shown with early behavioral intervention.

28 Nov 2012

Intramyocardial injection of organ-derived stem cells after AMI improves left ventricle function

A study published in the current issue of Cell Transplantation, now freely available on-line, has found that when mesenchymal cells derived from skeletal muscle (SM-MSCs) or adipose tissue (ADSCs) were injected into the heart muscle (myocardium) of separate groups of laboratory rats that had suffered a myocardial infarction, rats in both groups experienced significantly improved left ventricle function and smaller infarct size after cell therapy.

28 Nov 2012

Carnosic acid promotes eye health

Herbs widely used throughout history in Asian and early European cultures have received renewed attention by Western medicine in recent years. Scientists are now isolating the active compounds in many medicinal herbs and documenting their antioxidant and anti-inflammatory activities. In a study published in the journal Investigative Ophthalmology & Visual Science, Stuart A. Lipton, M.D., Ph.D. and colleagues at Sanford-Burnham Medical Research Institute (Sanford-Burnham) report that carnosic acid, a component of the herb rosemary, promotes eye health.

28 Nov 2012

High-resolution real-time images show how nerves may be damaged during earliest stages of MS

High-resolution real-time images show in mice how nerves may be damaged during the earliest stages of multiple sclerosis. The results suggest that the critical step happens when fibrinogen, a blood-clotting protein, leaks into the central nervous system and activates immune cells called microglia.

28 Nov 2012

State roundup: Conn. official says bulk buying prescription drugs could help budget

The state's chief fiscal watchdog is asking legislators and Gov. Dannel P. Malloy's administration to take a second look at how government purchases prescription medication -- and a proposal he believes could save more than $65 million over the next fiscal year.

28 Nov 2012

Investing in eyeglasses in developing nations could boost global economy, study shows

"Eliminating the worldwide shortage of eyeglasses could cost up to $28 billion, but would add more than $200 billion to the global economy, according to a study" conducted by researchers from Australia and the Johns Hopkins Bloomberg School of Public Health and published last month in the Bulletin of the World Health Organization, the New York Times reports.

28 Nov 2012

Study finds chemicals linked to cancer, learning problems and hormone disruption

A peer-reviewed study of the largest number of flame retardants ever tested in homes found that most houses had levels of at least one flame retardant that exceeded a federal health guideline. The journal Environmental Science & Technology will publish the study online on November 28, 12:01am Eastern.

28 Nov 2012

New investigational procedure may prolong life for patients with severe COPD

November is Chronic Obstructive Pulmonary Disease (COPD) Awareness Month. COPD, also known as emphysema, is the third leading cause of death in the United States, only behind heart disease and cancer. Right now, the only studied interventions that prolong life for patients with severe COPD are supplemental oxygen in people with low oxygen levels and lung volume reduction surgery (LVRS) in appropriately selected individuals.

28 Nov 2012

Medical Condition News

French National Center for Scientific Research scientist wins American Epilepsy Society award

Researchers discover alternative mechanism for Ras protein activation

Bayer completes recruitment of first cohort for BAY 86-6150 Phase II/III study in hemophilia

Yoga appears to be effective treatment for neck pain

Florbetapir PET scans can detect brain amyloid deposits associated with Alzheimer’s

Prevalence of mental health diagnoses increases with long duration of opioid use

Off label atypical antipsychotic use lacks safety and effectiveness in patients over 40

The Neuro clinician-scientists to further research on HIV/AIDS, Parkinson's

Digoxin increases risk of death in patients with atrial fibrillation

Study broadens understanding of how cells regulate X chromosome inactivation

Researchers aim to improve feeling of 'walking on marbles' for arthritis patients

Patients with RA more likely to have dislocation following hip replacement surgery

Cry acoustics may help identify infants at risk of autism

Intramyocardial injection of organ-derived stem cells after AMI improves left ventricle function

Carnosic acid promotes eye health

High-resolution real-time images show how nerves may be damaged during earliest stages of MS

State roundup: Conn. official says bulk buying prescription drugs could help budget

Investing in eyeglasses in developing nations could boost global economy, study shows

Study finds chemicals linked to cancer, learning problems and hormone disruption

New investigational procedure may prolong life for patients with severe COPD

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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