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New way to stimulate transplanted human stem cell-derived neurons into a rodent hippocampus

Researchers and patients look forward to the day when stem cells might be used to replace dying brain cells in Alzheimer's disease and other neurodegenerative conditions. Scientists are currently able to make neurons and other brain cells from stem cells, but getting these neurons to properly function when transplanted to the host has proven to be more difficult.

17 Nov 2012

Scientists discover new mode of action for enzymes immersed in cellular membranes

Johns Hopkins scientists have discovered a new mode of action for enzymes immersed in cellular membranes. Their experiments suggest that instead of recognizing and clipping proteins based on sequences of amino acids, these proteases' location within membranes gives them the unique ability to recognize and cut proteins with unstable structures.

17 Nov 2012

Study shows how Parkinson's spreads and leads to nerve cell death

Understanding how any disease progresses is one of the first and most important steps towards finding treatments to stop it. This has been the case for such brain-degenerating conditions as Alzheimer's disease. Now, after several years of incremental study, researchers at the Perelman School of Medicine, University of Pennsylvania have been able to piece together important steps in how Parkinson's disease (PD) spreads from cell to cell and leads to nerve cell death.

17 Nov 2012

Two studies investigate role of oxygen in cell transplantation

Two studies published in the current issue of Cell Transplantation, now freely available on-line, investigate the role of oxygen in cell transplantation.

17 Nov 2012

Study illuminates how Aldo and galectin-3 protein contribute to vascular remodeling, CHF

Cardiovascular disease will kill nearly 2.5 million people in the United States this year, according to the Centers for Disease Control. Over time, inflammation, collagen deposition and scar tissue formation can cause blood vessels to stiffen, a process called vascular fibrosis. Though researchers have known that the hormone aldosterone (Aldo) plays a role in this process, the precise mechanisms have been poorly understood.

17 Nov 2012

College of American Pathologists accredits NCH’s Biopathology Center

Biorepositories are highly complex research facilities with expert staff to process, store, characterize and secure biological specimens and their corresponding clinical information.

17 Nov 2012

Possible link between mind wandering and aging

Scientific studies have suggested that a wandering mind indicates unhappiness, whereas a mind that is present in the moment indicates well-being. Now, a preliminary UCSF study suggests a possible link between mind wandering and aging, by looking at a biological measure of longevity.

17 Nov 2012

Combination of Abraxane and gemcitabine improves survival of patients with pancreatic cancer

A new cancer drug combination demonstrated significant improvement in overall survival of late-stage pancreatic cancer patients compared to those receiving standard treatment, according to results of a Phase III clinical trial led by physicians from Scottsdale Healthcare's Virginia G. Cancer Center Clinical Trials, a partnership with the Translational Genomics Research Institute (TGen).

17 Nov 2012

Textile pressure ulcer prevention

The skin is the most versatile of our organs: It protects the body from environmental effects, contributes to the body's immune system and supports metabolic functions such as breathing.

17 Nov 2012

NCCBH now accepts nominations for National Council Awards of Excellence

The National Council for Community Behavioral Healthcare is now accepting nominations for individuals and organizations that qualify to achieve the most prestigious awards in behavioral healthcare — the National Council Awards of Excellence.

17 Nov 2012

Walgreens community-based programs help raise more than $1.3M in 2012 for JDRF

Walgreens, the nation's largest drugstore chain, and JDRF, the world's largest charitable funder of research toward curing, treating, and preventing type 1 diabetes (T1D) and its complications, today announced that Walgreens community-based programs helped raise more than $1.3 million in 2012 for JDRF.

17 Nov 2012

New study highlights parents' role in transmission of dentist fear in family

Fear of visiting the dentist is a frequent problem in paediatric dentistry. A new study confirms the emotional transmission of dentist fear among family members and analyses the different roles that mothers and fathers might play.

17 Nov 2012

Cancer Network, ONCOLOGY present two part primer report on targeted therapies in solid tumors

UBM Medica US announces that Cancer Network and the journal ONCOLOGY are presenting a two part primer report on targeted therapies in solid tumors.

17 Nov 2012

Tregs appears to play an important role in suppressing immune response in advance of sepsis

Following an infection, dysregulation of the immune system can result in a systemic inflammatory response and an often fatal condition called severe sepsis or septic shock. Sepsis is not uncommon, yet its cause and underlying immune dysfunction remain poorly understood.

17 Nov 2012

S100A4 protein triggers repair processes in the brain after injury

Researchers at the University of Copenhagen have found that a protein, known for causing cancer cells to spread around the body, is also one of the molecules that trigger repair processes in the brain.

17 Nov 2012

GW researcher gets NCI grant to study behavior of parasitic worm in bile duct cancer

Paul Brindley, Ph.D., professor of microbiology, immunology, and tropical medicine at the George Washington University School of Medicine and Health Sciences, was the recipient of a $1.7 million grant from the National Cancer Institute to study the behavior of a parasitic worm, rampant in Southeast Asia, known to cause infections that contribute to liver cancer.

16 Nov 2012

General guidelines to understand allergic skin conditions

Winter months can bring on the itch as cold weather and indoor heat dry out the skin. It's possible, suggests Chicago allergist, Brian Rotskoff, MD of Clarity Allergy Center, that your winter itch could be caused by more than just the weather. For some people itchy, dry skin is just that, but for others it can be a symptom of atopic dermatitis (eczema), contact dermatitis, or hives (urticaria).

16 Nov 2012

FDA approves Cook's Zilver PTX drug-eluting peripheral stent

Angiotech Pharmaceuticals, Inc. announced that its partner Cook Medical, Inc. received approval on November 15, 2012 from the U.S. Food and Drug Administration to market and sell the proprietary Zilver PTX drug-eluting peripheral stent, adding the United States to the list of over 50 markets, including the European Union and Japan, where Zilver PTX is approved for sale.

16 Nov 2012

New pneumococcal vaccine highly effective in infants

A new conjugate vaccine is highly effective (93–100%) at preventing invasive pneumococcal disease (IPD; meningitis, sepsis, bacteremic pneumonia, and other blood-borne infections) in infants younger than 2 years who are the most vulnerable to infection, according to new research published Online First in The Lancet.

16 Nov 2012

HUCPVC cell therapy more effective in restoring heart function after myocardial infarction

A study published this month by researchers at the University of Toronto and Toronto's Princess Margaret Hospital has shown that cells derived from the umbilical cord, "Human Umbilical Cord PeriVascular Cells" (HUCPVCs), are more effective in restoring heart function after an acute myocardial infarction (in common parlance, a heart attack) in a pre-clinical model than a similar cell population derived from bone marrow.

16 Nov 2012

Medical Condition News

New way to stimulate transplanted human stem cell-derived neurons into a rodent hippocampus

Scientists discover new mode of action for enzymes immersed in cellular membranes

Study shows how Parkinson's spreads and leads to nerve cell death

Two studies investigate role of oxygen in cell transplantation

Study illuminates how Aldo and galectin-3 protein contribute to vascular remodeling, CHF

College of American Pathologists accredits NCH’s Biopathology Center

Possible link between mind wandering and aging

Combination of Abraxane and gemcitabine improves survival of patients with pancreatic cancer

Textile pressure ulcer prevention

NCCBH now accepts nominations for National Council Awards of Excellence

Walgreens community-based programs help raise more than $1.3M in 2012 for JDRF

New study highlights parents' role in transmission of dentist fear in family

Cancer Network, ONCOLOGY present two part primer report on targeted therapies in solid tumors

Tregs appears to play an important role in suppressing immune response in advance of sepsis

S100A4 protein triggers repair processes in the brain after injury

GW researcher gets NCI grant to study behavior of parasitic worm in bile duct cancer

General guidelines to understand allergic skin conditions

FDA approves Cook's Zilver PTX drug-eluting peripheral stent

New pneumococcal vaccine highly effective in infants

HUCPVC cell therapy more effective in restoring heart function after myocardial infarction

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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