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Pancreatic B-cell dedifferentiation leads to decline in insulin production in type 2 diabetes

Scientists generally think that reduced insulin production by the pancreas, a hallmark of type 2 diabetes, is due to the death of the organ's beta cells. However, a new study by Columbia University Medical Center (CUMC) researchers shows that beta cells do not die but instead revert to a more fundamental, undifferentiated cell type.

15 Sep 2012

CINJ experts available to discuss prevention and treatment of breast cancer

The Cancer Institute of New Jersey (CINJ) is making experts available to discuss the risks, and options for treatment and prevention surrounding breast cancer. According to the American Cancer Society 227,000 women nationwide will be diagnosed with the disease this year, and while the disease affects mostly women, men also can be diagnosed with breast cancer.

15 Sep 2012

Sanford-Burnham scientist to receive NIH’s New Innovator Award

The National Institutes of Health (NIH) Office of the Director today announced that Duc Dong, Ph.D., assistant professor at Sanford-Burnham Medical Research Institute (Sanford-Burnham), will receive a New Innovator Award.

15 Sep 2012

CBH first hospital in Central Kentucky to perform transcatheter aortic valve replacement

CBH is the first hospital in Central Kentucky to perform the transcatheter aortic valve replacement (TAVR) procedure. Four patients with diseased aortic heart valves who were deemed too sick to withstand conventional open-heart surgery to replace their valves have undergone this new heart valve replacement procedure at Central Baptist Hospital.

15 Sep 2012

UMDNJ, Proteonomix to conduct UMK-121 Phase 1 trial in end-stage liver disease

Proteonomix, Inc., a biotechnology company focused on developing therapeutics based upon the use of human cells and their derivatives, today announced it has entered into an agreement with Piscataway, N.J.-based University of Medicine and Dentistry of New Jersey (UMDNJ) to conducted a Phase 1 clinical trial with its proprietary, patent-pending mobilization technology UMK-121 in patients with end-stage liver disease (ESLD).

15 Sep 2012

Experimental diabetes drug shows promise against Alzheimer's

A drug designed for diabetes sufferers could have the potential to treat neurodegenerative diseases like Alzheimer's, a study by scientists at the University of Ulster has revealed.

15 Sep 2012

A mysterious form of cell death uncovers prime suspect for new cancer drug development

A mysterious form of cell death, coded in proteins and enzymes, led to a discovery by UNC researchers uncovering a prime suspect for new cancer drug development.

15 Sep 2012

Global response to NCDs has gained momentum over past year

"Cancers, cardiovascular diseases, chronic lung diseases and diabetes -- four of the biggest killers among the group together known as non-communicable diseases (NCDs) -- have emerged as one of the greatest social and economic development challenges of this century," George Alleyne, director emeritus of PAHO, and Nils Daulaire, director of the Office of Global Affairs at the Department of Health & Human Services and the U.S. representative on the WHO's Executive Board, write in the Huffington Post's "Impact" blog.

14 Sep 2012

Genomes of lung cancer smokers have more mutations

Lung cancer patients with a history of smoking have 10 times more genetic mutations in their tumors than those with the disease who have never smoked, according to a new study from Washington University School of Medicine in St. Louis.

14 Sep 2012

Increasing perceived control may reduce risk of complications after acute coronary syndrome

Patients admitted to hospital with obstructed heart arteries were three times more likely to experience complications when they were in hospital if they felt they were not in control of their condition, according to research published in the October issue of the Journal of Advanced Nursing.

14 Sep 2012

Reading labels on food products can prevent obesity

An international team of scientists headed from the University of Santiago de Compostela ensures that reading the labels on food products is linked to obesity prevention, especially in women. According to the study which used data from the USA, female consumers who consult food labels weigh nearly 4 kilograms less.

14 Sep 2012

Cessation of drinking may reduce risk of oesophageal cancer

Cancer of the oesophagus is becoming more common in Europe and North America. Around 7,800 people in the UK are diagnosed each year. The exact causes of this cancer aren't fully understood. It appears to be more common in people who have long-term acid reflux (backflow of stomach acid into the oesophagus).

14 Sep 2012

ASN's top five recommendations to avoid wasteful and harmful medical interventions

Earlier this year, the American Society of Nephrology (ASN), the world's leading kidney organization, joined other groups in a campaign to help health care professionals and patients avoid wasteful and sometimes harmful medical interventions. A new article in the Clinical Journal of the American Society of Nephrology (CJASN) outlines the ASN's top five recommendations for the campaign and the rationale behind them.

14 Sep 2012

Trigeminal Nerve Stimulation: an interview with Dr Leon Ekchian, President and CEO of NeuroSigma

Trigeminal Nerve Stimulation (TNS) is a novel medical treatment in which mild electrical signals stimulate branches of the trigeminal nerve in order to change the activity of targeted brain regions. The trigeminal nerve is the largest cranial nerve, and provides sensation to the face and head. Because it is a large sensory nerve, the trigeminal offers a high-bandwidth pathway for electrical signals to enter the brain. The brain areas targeted by TNS are known to play key roles in seizures, mood, and attention.

14 Sep 2012

Rusk to host community events in recognition of National Rehabilitation Awareness Week

Rusk Rehabilitation at NYU Langone Medical Center (Rusk) will host a series of community events in recognition of National Rehabilitation Awareness Week, September 16-22.

14 Sep 2012

New initiative to improve in-hospital management of stroke across VA medical system

Researcher-clinicians from the Regenstrief Institute, the Department of Veterans Affairs and Indiana University School of Medicine are leading a national effort to coordinate and organize acute stroke care across the entire VA medical system.

14 Sep 2012

Lilly, Boehringer Ingelheim announce availability of My Well Planner for adults with type 2 diabetes

Boehringer Ingelheim Pharmaceuticals, Inc. and Eli Lilly and Company today announce the availability of a new online program offering customized educational content to help adults with type 2 diabetes make simple lifestyle changes to improve their health.

14 Sep 2012

Dual role of ghrelin in anxiety behavior is context-dependent

Ghrelin is a hormone released by the lining of the stomach that promotes feeding behavior. Decreasing ghrelin levels could potentially help combat obesity -- in fact, a vaccine that lowers ghrelin levels in order to reduce appetite is being studied as a treatment for obesity.

14 Sep 2012

Hyperuricemia associated with more severe hepatic ATP depletion in response to fructose intake

Obese patients with type 2 diabetes who consume higher amounts of fructose display reduced levels of liver adenosine triphosphate (ATP)—a compound involved in the energy transfer between cells.

14 Sep 2012

Researchers regenerate axons at spinal cord injury site

In a study at the University of California, San Diego and VA San Diego Healthcare, researchers were able to regenerate "an astonishing degree" of axonal growth at the site of severe spinal cord injury in rats.

14 Sep 2012

Medical Condition News

Pancreatic B-cell dedifferentiation leads to decline in insulin production in type 2 diabetes

CINJ experts available to discuss prevention and treatment of breast cancer

Sanford-Burnham scientist to receive NIH’s New Innovator Award

CBH first hospital in Central Kentucky to perform transcatheter aortic valve replacement

UMDNJ, Proteonomix to conduct UMK-121 Phase 1 trial in end-stage liver disease

Experimental diabetes drug shows promise against Alzheimer's

A mysterious form of cell death uncovers prime suspect for new cancer drug development

Global response to NCDs has gained momentum over past year

Genomes of lung cancer smokers have more mutations

Increasing perceived control may reduce risk of complications after acute coronary syndrome

Reading labels on food products can prevent obesity

Cessation of drinking may reduce risk of oesophageal cancer

ASN's top five recommendations to avoid wasteful and harmful medical interventions

Trigeminal Nerve Stimulation: an interview with Dr Leon Ekchian, President and CEO of NeuroSigma

Rusk to host community events in recognition of National Rehabilitation Awareness Week

New initiative to improve in-hospital management of stroke across VA medical system

Lilly, Boehringer Ingelheim announce availability of My Well Planner for adults with type 2 diabetes

Dual role of ghrelin in anxiety behavior is context-dependent

Hyperuricemia associated with more severe hepatic ATP depletion in response to fructose intake

Researchers regenerate axons at spinal cord injury site

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective

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