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Genetic analysis reveals hidden causes of chronic kidney disease in adults

Chronic kidney disease (CKD) is extremely prevalent among adults, affecting over 800 million individuals worldwide.

3 Apr 2024

Lurie Children's Hospital administers first gene therapy for Duchenne muscular dystrophy in Illinois

On March 27, 2024, Ann & Robert H. Lurie Children's Hospital of Chicago treated its first patient with ELEVIDYS (delandistrogene moxeparvovec-rokl), the first gene therapy for Duchenne muscular dystrophy – a rare, genetic disease characterized by progressive muscle damage and weakness.

3 Apr 2024

New research links social factors to cardiovascular risk in Asian American adults

Having more unfavorable social determinants of health, such as being unemployed, uninsured or not having education beyond high school, was associated with an increased likelihood of having risk factors for cardiovascular disease among Asian American adults, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

3 Apr 2024

New model predicts kidney injury risk in cancer patients on cisplatin

Researchers have developed a new model predicting severe acute kidney injury in patients treated with cisplatin, incorporating factors like hypomagnesemia to improve patient care and outcomes.

3 Apr 2024

Balanced diet linked to better brain health and cognition, large-scale study shows

Study utilizing the UK Biobank data identifies four dietary patterns, revealing the balanced diet subtype promotes superior cognitive functions and mental health outcomes compared to starch-free, vegetarian, or high-protein-low-fiber diets.

3 Apr 2024

Systemic Inflammation Index: A new hope for autoimmune disease management

A routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of debilitating autoimmune diseases.

2 Apr 2024

Atomic-level structural models of enzymes provide disease insights

When nucleic acids like DNA or RNA build up in a cell's cytoplasm, it sets off an alarm call for the immune system.

2 Apr 2024

Statins slightly up diabetes risk but cardiovascular benefits remain, finds study

Statin therapy modestly increases diabetes diagnoses but offers substantial cardiovascular benefits, outweighing the slight rise in glycemia, especially in those near diabetes diagnostic thresholds.

2 Apr 2024

How gut microbiome influences obesity onset differently in men and women

New research being presented at this year's European Congress on Obesity (ECO) in Venice, Italy (12-15 May) identifies changes in the composition of gut bacteria that may play a key role in the onset and development of obesity, with differences in men and women, which might affect the metabolism of different nutrients and therefore the presence of bioactive molecules in the gut that influence the development of metabolic disease.

2 Apr 2024

Low vitamin D in children linked to higher atopic dermatitis risk, study finds

Study reveals that low vitamin D levels in early childhood are linked to increased allergen sensitization and a higher risk of developing atopic dermatitis.

2 Apr 2024

Defining how exercise affects cardiovascular health in people using wheelchairs

Delphia Brown (left) exercises at the Stephen A. Orthwein Center, a wheelchair-accessible gym in St. Louis operated by Paraquad, an organization that helps people with disabilities achieve independence.

2 Apr 2024

Advancing osteosarcoma prognosis with AI-assisted tumor cell density analysis

Researchers at Kyushu University have developed and validated a machine-learning model that can accurately evaluate the density of surviving tumor cells after treatment in pathological images of osteosarcoma - the most prevalent malignant bone tumor.

2 Apr 2024

Microwave ablation offers a promising treatment option for multifocal papillary thyroid cancer

In a 10-center study, microwave ablation offered progression free survival rates and fewer complications than surgery in the treatment of a form of thyroid cancer known as papillary thyroid carcinoma (PTC), according to research published today in Radiology, a journal of the Radiological Society of North America.

2 Apr 2024

Certain gut bacteria may help lower cholesterol and heart disease risk

Changes in the gut microbiome have been implicated in a range of diseases including type 2 diabetes, obesity, and inflammatory bowel disease.

2 Apr 2024

Novel antibiotic-infused hydrogel kills bacteria and promotes cell growth

Hydrogels are popular for use in skin ailments and tissue engineering. These polymer-based biocompatible materials are useful for their abilities to retain water, deliver drugs into wounds, and biodegrade.

2 Apr 2024

Researchers develop tool to identify osteoarthritis pain in horses

Morris Animal Foundation-funded researchers introduced a straightforward questionnaire to help horse owners identify and monitor signs of osteoarthritis pain in their equine companions.

2 Apr 2024

E-cigarette use linked to increased risk of heart failure, large study finds

People who use e-cigarettes are significantly more likely to develop heart failure compared with those who have never used them, according to one of the largest prospective studies to date investigating possible links between vaping and heart failure.

2 Apr 2024