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Glycogen metabolism in neurons emerges as key to fighting Alzheimer's

A new study from scientists at the Buck Institute for Research on Aging has revealed a surprising player in the battle against Alzheimer's disease and other forms of dementia: brain sugar metabolism.

1 Jul 2025

AI tool matches doctors in accurately outlining lung tumors on CT scans

In radiation therapy, precision can save lives. Oncologists must carefully map the size and location of a tumor before delivering high-dose radiation to destroy cancer cells while sparing healthy tissue.

1 Jul 2025

Smart pen detects early signs of Parkinson’s through handwriting

Every year, tens of thousands of people with signs of Parkinson's disease go unnoticed until the incurable neurodegenerative condition has already progressed.

30 Jun 2025

Brain stimulation restores synaptic plasticity in Alzheimer’s mouse model

Alzheimer's disease (AD) is a debilitating neurodegenerative condition that affects a significant proportion of older people worldwide. Synapses are points of communication between neural cells that are malleable to change based on our experiences.

30 Jun 2025

AI system offers new hope for diagnosing PTSD in children

Diagnosing post-traumatic stress disorder in children can be notoriously difficult. Many, especially those with limited communication skills or emotional awareness, struggle to explain what they're feeling.

30 Jun 2025

Oleic acid from olive oil reduces infection-related bone loss with age

A mouse study shows that dietary oleic acid, a key Mediterranean diet component, protects against age-related bone and microbiome damage triggered by periodontal infection. In contrast, a Western-style palmitic acid diet worsens bone loss and destabilizes the gut microbiome.

30 Jun 2025

Shingles and RSV vaccines with AS01 adjuvant reduce dementia risk

Researchers found that older adults who received AS01-adjuvanted shingles or RSV vaccines had a significantly lower risk of developing dementia within 18 months compared to flu vaccine recipients. The protective effect is likely linked to the AS01 adjuvant itself, highlighting new avenues for dementia prevention.

30 Jun 2025

One in six people worldwide affected by loneliness, WHO report reveals

The World Health Organization (WHO) Commission on Social Connection has released its global report revealing that 1 in 6 people worldwide is affected by loneliness, with significant impacts on health and well-being.

30 Jun 2025

FAU researchers secure key grants to target new gene in the fight against glioblastoma

Florida Atlantic University researchers have secured two key grants to investigate targeting a gene for the first time as a new approach to treat glioblastoma, a very aggressive and fast-growing type of brain cancer.

30 Jun 2025

New trial offers hope for effective treatment of spinal cord injuries

Spinal cord injuries are currently incurable with devastating effects on people's lives, but now a trial at Waipapa Taumata Rau, University of Auckland offers hope for an effective treatment.

30 Jun 2025

New AI tool helps clinicians identify brain activity patterns linked to nine types of dementia

Mayo Clinic researchers have developed a new artificial intelligence (AI) tool that helps clinicians identify brain activity patterns linked to nine types of dementia, including Alzheimer's disease, using a single, widely available scan - a transformative advance in early, accurate diagnosis.

30 Jun 2025

Urine-based DNA test predicts bladder cancer recurrence after immunotherapy

In a multi-institutional study published in Science Direct, researchers revealed that testing urine-based tumor DNA (utDNA) can help predict which bladder cancer patients are at higher risk for recurrence after treatment.

30 Jun 2025

Comprehensive study maps genetic mutations in SLC13A5 linked to epilepsy

Citrate is essential for the metabolism and development of neurons. A membrane transport protein called SLC13A5 plays a central role in this process and has previously been linked to a particularly severe form of epileptic encephalopathy.

30 Jun 2025

Vegetables and dairy may lower endometriosis risk

A major umbrella review shows that higher intake of vegetables and dairy products is linked to a lower risk of endometriosis, while butter and high caffeine intake appear to increase risk. However, the evidence remains weak due to limitations in existing observational studies.

30 Jun 2025

Gene therapy shows promise for reducing stroke risk in patients with sickle cell disease

Gene therapy for sickle cell disease may help improve a major contributing factor to stroke risk in patients, reports a new study from St. Jude Children's Research Hospital.

30 Jun 2025

Coffee’s hidden compounds could help fight type 2 diabetes

A comprehensive review of nearly 150 studies reveals that coffee polyphenols may help regulate blood sugar and reduce inflammation linked to type 2 diabetes. However, most evidence comes from preclinical research, and robust clinical trials are needed to confirm benefits.

29 Jun 2025

Just 150 minutes of exercise a week could reverse prediabetes

Engaging in more than 150 minutes of physical activity per week quadrupled the odds of reversing prediabetes to normal glucose levels in Colombian adults. Higher BMI and HbA1c remained strong barriers to reversal, highlighting the power of lifestyle interventions.

29 Jun 2025

Are sweeteners really making our children’s diets healthier?

Higher consumption of low-calorie sweetened (LCS) products among UK children was not consistently linked to reduced free sugar intake, and may reflect less healthy overall dietary patterns. Over 11 years, improvements in dietary quality were slowest among those consuming the most LCS products.

29 Jun 2025

Risk factors associated with emergency presentations following malignant skin cancer

Emergency department (ED) presentations are associated with higher cancer mortality. This study aimed to investigate the prevalence, frequency, and risk factors in Australian patients diagnosed with malignant skin cancers.

27 Jun 2025

Organ chip technology accurately predicts chemotherapy response in esophageal adenocarcinoma patients

Esophageal adenocarcinoma (EAC), one of two major forms of esophageal cancer, is the sixth most deadly cancer worldwide for which no effective targeted therapy exists.

27 Jun 2025