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Gene editing restores hearing and balance in adult mice with DFNA41 deafness

Zheng-Yi Chen, DPhil, associate scientist at the Eaton-Peabody Laboratories, and Ines and Fredrick Yeatts Chair in Otolaryngology, at Mass Eye and Ear, is the senior and co-corresponding author of a paper published in the Journal of Clinical Investigation, "Single Dose Genome Editing Therapy Rescues Auditory and Vestibular Functions in Adult Mice with DFNA41 Deafness."

14 Aug 2025

Brain organoids reveal early changes in familial Alzheimer’s disease

Alzheimer's disease (AD) is the most common neurodegenerative disease in older people, affecting up to 1 in 20 individuals aged 65 and above. In addition to environmental and lifestyle factors, genetic mutations can predispose an individual to AD and some rare forms of inherited "familial" AD (fAD) are caused by known genetic mutations, with these affected individuals developing AD with high probability and at relatively young age.

14 Aug 2025

Most Americans unaware that HPV causes multiple types of cancer

The human papillomavirus (HPV) can cause six types of cancer.

14 Aug 2025

Vagus nerve modulation can effectively halt the progression of cancer-associated cachexia

The Terasaki Institute for Biomedical Innovation announces a significant advancement in addressing the fight against cancer-associated cachexia (CAC), a life-threatening syndrome responsible for over one-third of cancer-related deaths.

14 Aug 2025

Microbial DNA signature in the blood differentiates primary liver cancer from metastatic colorectal cancer

Determining whether a cancerous tumor originated in a given location or spread there from another tissue or organ in the body is important when assessing the likely course of a patient's disease.

14 Aug 2025

Engineered CD40 antibody shrinks tumors and induces remission

Over the past 20 years, a class of cancer drugs called CD40 agonist antibodies have shown great promise-and induced great disappointment.

14 Aug 2025

Frailty raises the risk of lung attacks and death in smokers

A new research paper was published in Volume 17, Issue 7, of Aging (Aging-US) on July 3, 2025, titled "Frailty associates with respiratory exacerbations and mortality in the COPDGene cohort."

14 Aug 2025

Diabetes drugs linked to higher risk of rare optic nerve damage

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14 Aug 2025

Colorectal cancer rates nearly triple among younger people in Sweden

According to a study by Karolinska Institutet, nearly three times as many people under the age of 50 in Sweden are diagnosed with colorectal cancer today compared with the early 1990s.

14 Aug 2025

Triglycerides identified as direct cause of abdominal aortic aneurysms

High levels of triglycerides, the most common type of fat in the body and the foods we eat, directly cause abdominal aortic aneurysms, according to a study in mouse models led by Michigan Medicine.

14 Aug 2025

COVID-19 increases risk of asthma and sinusitis while vaccination offers protection

People who have had COVID-19 are at increased risk of developing certain inflammatory diseases of the airways, such as asthma, hay fever and chronic sinusitis.

14 Aug 2025

Genicular artery embolization relieves chronic knee pain caused by osteoarthritis

A procedure performed under mild sedation in less than two hours by an interventional radiologist relieves chronic knee pain caused by osteoarthritis, an NYU Langone Health study shows.

14 Aug 2025

PSMA PET/CT improves outcomes for men with recurrent prostate cancer

A new study from Denmark shows for the first time that men with biochemically recurrent prostate cancer who undergo PSMA PET/CT before salvage radiotherapy have improved survival rates compared to those who do not.

14 Aug 2025

New study explains why neuroblastoma returns years later

Cancer is the leading cause of disease-related death in childhood. This is in part due to cancer-associated genes called oncogenes that can be found far from chromosomes in cell nuclei on ring-shaped DNA inside tumor cells.

14 Aug 2025

Study identifies why stroke impairs ability to use word meanings in reading

A key discovery about the impact of stroke on a person's ability to read reveals why a deficit occurs – a finding that presents a possible opportunity for new therapeutic strategies to help people recover one of the most important life skills.

13 Aug 2025

Griffith University launches groundbreaking treatment trial for spinal cord injury

A Phase 1 human clinical trial to treat chronic spinal cord injury, the first of its kind in the world, has commenced to test the efficacy and safety of a revolutionary new treatment using nasal cells.

13 Aug 2025

Research shows GLP-1 drugs safeguard vision despite small retinopathy risk

A large study of over 185,000 adults with type 2 diabetes found that GLP-1 receptor agonist use was linked to a slight increase in new diabetic retinopathy cases but fewer severe eye complications, including a reduced risk of blindness. Patients with existing retinopathy on these drugs also needed fewer invasive eye treatments over two years.

13 Aug 2025

New bioimaging device shows promise for detecting eye and heart conditions

If you've been to a routine eye exam at the optometrist's office, chances are you've had to place your chin and forehead up close to a bioimaging device.

13 Aug 2025

High-dose vitamin D in pregnancy likely cuts childhood wheeze risk, but infant supplements fall short

A Cochrane review of 18 randomized trials found that high-dose vitamin D during pregnancy likely reduces the risk of childhood wheeze, a key early symptom of asthma. However, vitamin D supplementation in infants and young children showed uncertain benefits for asthma prevention.

13 Aug 2025

Pregabalin raises heart failure risk in older adults compared to gabapentin, study finds

A large Medicare cohort study found that older adults prescribed pregabalin had a significantly higher risk of developing heart failure compared to those prescribed gabapentin. The elevated risk was most pronounced in individuals with pre-existing cardiovascular disease, especially women and White patients.

13 Aug 2025

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Medical Condition News

Gene editing restores hearing and balance in adult mice with DFNA41 deafness

Brain organoids reveal early changes in familial Alzheimer’s disease

Most Americans unaware that HPV causes multiple types of cancer

Vagus nerve modulation can effectively halt the progression of cancer-associated cachexia

Microbial DNA signature in the blood differentiates primary liver cancer from metastatic colorectal cancer

Engineered CD40 antibody shrinks tumors and induces remission

Frailty raises the risk of lung attacks and death in smokers

Diabetes drugs linked to higher risk of rare optic nerve damage

Colorectal cancer rates nearly triple among younger people in Sweden

Triglycerides identified as direct cause of abdominal aortic aneurysms

COVID-19 increases risk of asthma and sinusitis while vaccination offers protection

Genicular artery embolization relieves chronic knee pain caused by osteoarthritis

PSMA PET/CT improves outcomes for men with recurrent prostate cancer

New study explains why neuroblastoma returns years later

Study identifies why stroke impairs ability to use word meanings in reading

Griffith University launches groundbreaking treatment trial for spinal cord injury

Research shows GLP-1 drugs safeguard vision despite small retinopathy risk

New bioimaging device shows promise for detecting eye and heart conditions

High-dose vitamin D in pregnancy likely cuts childhood wheeze risk, but infant supplements fall short

Pregabalin raises heart failure risk in older adults compared to gabapentin, study finds

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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