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T cells play key role in early stages of Parkinson’s disease

Your T cells work hard to fight disease. Unfortunately, "friendly fire" from T cells can sometimes harm the body's healthy tissues.

19 Jun 2025

C-Path’s TRxA awards $250,000 grant to develop novel treatment for type 1 diabetes

Critical Path Institute's (C-Path) Translational Therapeutics Accelerator (TRxA) proudly announced today a $250,000 grant award aimed at developing a novel treatment for type 1 diabetes (T1D).

19 Jun 2025

Intermittent fasting shows similar weight loss benefits to traditional diets

Intermittent fasting diets appear to have similar benefits to traditional calorie-restricted diets for weight loss, suggests an analysis of trial evidence published by The BMJ today.

19 Jun 2025

How early-life factors raise lifelong diabetes risks in youth

The surge in diabetes among young people highlights critical gaps in care and the urgent need for comprehensive preventative actions to address this crisis.

19 Jun 2025

Cognitive decline tied to gut microbes and nutritional access

A new study led in part by Mount Sinai researchers has found a compelling link between the composition of the gut microbiome and the risk of cognitive impairment (RCI) in adults, underscoring the complex role that both biology and social determinants-such as food insecurity-play in brain health.

18 Jun 2025

New screening method for Parkinson's analyzes odors in ear wax

Most treatments for Parkinson's disease (PD) only slow disease progression. Early intervention for the neurological disease that worsens over time is therefore critical to optimize care, but that requires early diagnosis.

18 Jun 2025

Researchers explore new approach to target rare epileptic disorders

Humans have tens of thousands of genes, many of which produce proteins essential to basic bodily functions.

18 Jun 2025

Can salt substitutes lower blood pressure in diabetes? A new Cochrane review aims to find out

Researchers will systematically review whether replacing regular sodium salt with alternatives like potassium or magnesium salts helps lower blood pressure in adults with diabetes. The protocol outlines a rigorous plan to evaluate blood pressure effects, safety, and adherence using data from RCTs and quasi-RCTs.

18 Jun 2025

Uppsala researchers create 3D-printed human nerve tissue model

With the aid of a 3D printer, researchers at Uppsala University have succeeded in creating a model that resembles human nerve tissue.

18 Jun 2025

Can a Japanese diet help with depression? Large study says yes

A large cross-sectional study of 12,499 Japanese workers found that higher adherence to traditional or modified Japanese diets was associated with a lower prevalence of depressive symptoms. The findings suggest that culturally rooted dietary patterns may support mental well-being, especially among educated adults.

18 Jun 2025

Equal access, unequal impact: Parkinson’s hits minorities harder in the UK

Researchers in East London found that South Asian and Black Parkinson’s disease patients experience more severe motor and cognitive symptoms than White patients. Despite similar access to diagnosis, disparities persist, highlighting the need for more inclusive and culturally sensitive care.

18 Jun 2025

Inhibiting RNA Polymerase 1 suppresses tumor growth in hard-to-treat cancers

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel therapies targeting hard-to-treat cancers.

18 Jun 2025

Immune cell signatures explain variations in systemic sclerosis severity

Treating rare diseases can be complicated at the best of times, and it gets even more complicated when different patients with the same disease exhibit different symptoms.

18 Jun 2025

Living near microplastic polluted waters linked to higher risk of heart and metabolic diseases

Living in a U.S. coastal county bordered by ocean waters with very high concentrations of microplastics may increase the risk of heart and metabolic diseases, such as Type 2 diabetes, coronary artery disease and stroke.

18 Jun 2025

New switchable CAR-T therapy enters phase 1 trial for advanced breast cancer

The Calibr-Skaggs Institute for Innovative Medicines, the drug development division of Scripps Research, today announced a milestone in cancer treatment with the dosing of the first patient in a phase 1 trial (NCT06878248) evaluating CLBR001 + ABBV-461, a modular, switchable chimeric antigen receptor T cell (sCAR-T) therapy in patients with advanced or metastatic breast cancer who have no suitable treatment options.

18 Jun 2025

CAR T-cell therapy successfully treats rare autoimmune disease of the peripheral nervous system

Physicians from Bochum have used a cancer treatment method to treat severe autoimmune diseases.

18 Jun 2025

Interferon pathway genes linked to treatment success in juvenile arthritis

A set of genes that could be used to help doctors predict which children will respond well to treatment for juvenile idiopathic arthritis (JIA) have been identified by researchers at UCL and Great Ormond Street Hospital for Children (GOSH), who are part of the CLUSTER Consortium.

18 Jun 2025

Heart scan study reveals low-fiber diets drive dangerous heart plaques

A Swedish study links low-fiber, high-red meat diets to increased coronary artery plaque risk, highlighting the importance of dietary choices for heart health.

18 Jun 2025

Grammatical errors could aid in the early detection of schizophrenia

Meta-analysis shows syntax deficits in schizophrenia, emphasizing the role of language in diagnosis and the development of effective therapeutic strategies.

18 Jun 2025

Compound-level diet analysis sheds light on hidden triggers in IBD

Dutch researchers identified specific food compounds that influence remission and flare risk in patients with inflammatory bowel disease. The study shows compound-level dietary analysis could help personalize IBD management and clarify conflicting advice about diet.

18 Jun 2025