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Targeting ADAM10 may offer hope for retinal disease treatment

New research has found that the endothelial cell-specific A disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) regulates abnormal blood vessel growth in the damaged retina, which can cause vision loss or impairment.

25 Jun 2025

Fusion genes found to be pivotal players in cancer development

Fusion genes, arising from abnormal chromosomal rearrangements, are gaining recognition as pivotal players in cancer development. These genetic alterations result in the creation of hybrid genes with altered functions, often driving tumor progression.

25 Jun 2025

Ribosome biogenesis plays critical role in liver health and disease progression

This new review article highlights the critical role of ribosome biogenesis in liver health and disease progression.

25 Jun 2025

Study finds nearly double risk of depression and anxiety in autoimmune patients

Living with an autoimmune disease is linked to a near doubling in the risk of persistent mental health issues, such as depression, generalised anxiety, and bipolar disorder, with these risks higher in women than in men, finds a large population-based UK study, published in the open access journal BMJ Mental Health.

25 Jun 2025

Researchers link brain waste clearance to early Alzheimer’s damage

A crucial link between the brain's cleaning system and deterioration of neurons associated with Alzheimer's disease has been discovered by University of Queensland researchers.

25 Jun 2025

Plant-based diets may help prevent erectile dysfunction

A narrative review in The Journal of Nutrition suggests that whole-food plant diets may help prevent or improve erectile dysfunction (ED) by supporting vascular health and reducing risk factors such as LDL cholesterol and inflammation. However, most evidence is observational, and more clinical trials are needed.

25 Jun 2025

Is aspartame safe for blood sugar? Study answers the big question

A major systematic review and meta-analysis found that aspartame has little to no effect on blood glucose, insulin, or appetite-regulating hormones in humans. Evidence certainty is very low, with no significant long-term metabolic impact identified.

25 Jun 2025

Scientists create ALS on a chip to uncover disease clues

Using stem cells from patients with ALS (amyotrophic lateral sclerosis), Cedars-Sinai has created a lifelike model of the mysterious and fatal disease that could help identify a cause of the illness as well as effective treatments.

24 Jun 2025

Flexible wireless implant offers hope for chronic pain sufferers

Chronic pain is a debilitating condition that severely impacts quality of life, often leading to reliance on opioid medications with their severe side effects and addiction risks.

24 Jun 2025

Once-monthly obesity injection shows double-digit weight loss in major clinical trial

Researchers found that once-monthly maridebart cafraglutide led to substantial weight loss and improved glycemic control in adults with obesity, with or without diabetes, in a phase 2 randomized trial. The drug demonstrated an acceptable safety profile and supports further study in phase 3 trials.

24 Jun 2025

Unhealthy teen diets reshape the brain and drive lifelong eating habits, study finds

Adolescent diets high in fat and sugar disrupt the development of the prefrontal cortex and hippocampus, impacting cognition, memory, and impulse control. These brain changes can promote unhealthy eating behaviors and obesity risk that persist into adulthood.

24 Jun 2025

New PET/CT imaging technique enables early detection of multiple forms of cardiomyopathy

A new PET/CT imaging technique that visualizes activated fibroblasts in the heart muscle enables early detection of multiple forms of cardiomyopathy, according to research presented at the Society of Nuclear Medicine and Molecular Imaging 2025 Annual Meeting.

24 Jun 2025

Stress-activated gene damages insulin-producing cells in type 2 diabetes

Stress does no one - not even your insulin-producing cells - any good.

24 Jun 2025

Newborns and Alzheimer's patients have elevated blood levels of phosphorylated tau

Newborn babies and patients with Alzheimer's disease share an unexpected biological trait: elevated levels of a well-known biomarker for Alzheimer's.

24 Jun 2025

Novel combination therapy targets m6A pathway to combat joint erosion in rheumatoid arthritis

A recent study published in Engineering has shed light on a novel combination therapy for rheumatoid arthritis (RA) that significantly reduces bone destruction by targeting the m6A methylation pathway.

24 Jun 2025

New KRAS mutation discovery opens door to targeted colon cancer therapies

Scientists at Fox Chase Cancer Center have identified a mutation in a common oncogene - a gene that can cause cancer - that may play an important role in colon cancer. Researchers also showed how this mutation could be targeted therapeutically.

24 Jun 2025

New AI tool characterizes the diversity of individual cells within tumors

A multinational team of researchers, co-led by the Garvan Institute of Medical Research, has developed and tested a new AI tool to better characterize the diversity of individual cells within tumors, opening doors for more targeted therapies for patients.

24 Jun 2025

Genetic markers show promise in predicting mood disorder treatment outcomes

In a comprehensive Genomic Press Thought Leaders Invited Review, researchers have synthesized findings from dozens of studies examining how genetic markers for mood disorders influence treatment outcomes and clinical features across major psychiatric conditions.

24 Jun 2025

Alcoholic liver disease exacerbates HBV reactivation and worsens outcomes in liver transplant recipients

A recent study published in Engineering has shed light on the impact of alcoholic liver disease (ALD) on post-transplant hepatitis B virus (HBV) reactivation and survival outcomes in patients with hepatocellular carcinoma (HCC).

24 Jun 2025

Study identifies potential way to slow or block progression of age-related macular degeneration

A new study from Washington University School of Medicine in St. Louis identifies a possible way to slow or block progression of age-related macular degeneration, a leading cause of blindness in people over age 50.

24 Jun 2025