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Immunogenicity predictions reveal SARS-CoV-2 CD8+ T-cell epitopes

In a recent study posted to the bioRxiv* pre-print server, researchers identified several new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epitopes displayed on human leukocyte antigens class I (HLA-I) molecules.

26 May 2022

Model predicts scenarios that reveal the benefit of updating COVID vaccines

In a recent study posted to the bioRxiv* preprint server, scientists analyzed the necessity of revamping the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines to tackle the current dominant circulating viral variants.

26 May 2022

Mucosal COVID vaccine candidate powerfully protective in macaques

A recent research paper posted to the bioRxiv* preprint server illustrated the protective efficacy of the intranasal pediatric parainfluenza virus-vectored coronavirus disease 2019 (COVID-19) vaccine prospect, B/HPIV3/S-6P, in macaques.

26 May 2022

Study shows glomerulonephritis after SARS-CoV-2 mRNA vaccination likely coincidental

In a recent study posted to the medRxiv* pre-print server, researchers assessed whether messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccines increase the incidence of glomerulonephritis against the null hypothesis stating any observed temporal association between the two phenomena was purely coincidental.

26 May 2022

SARS-CoV-2 variants BA.4 and BA.5 show substantial immune escape compared with BA.1 and BA.2

In a recent study posted to the bioRxiv* pre-print server, researchers characterized the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concern (VOC) Omicron’s new sub-lineages, BA.4, BA.5, and BA.3.

26 May 2022

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

A recent study posted to the bioRxiv* preprint server illustrated that specific chemokine antibodies aid in recognizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) convalescent individuals with a desirable disease course.

26 May 2022

A 6.4 million genome analysis predicts dominant SARS-CoV-2 variants

In this new study in the journal Science, researchers have developed a hierarchical Bayesian regression model, named, PyR0, which can analyze the complete set of publicly available SARS-CoV-2 genomes.

26 May 2022

Scientists discover a gene defect that results in allergic and autoimmune disease

Inflammation of the skin and the esophagus, food allergy and asthma are just some of the symptoms of a now 12-year-old boy who was the first to have a mutation on the IL-33 gene. An international team led by a physician from the Karl Landsteiner University for Health Sciences, Krems, discovered this new disease entity.

26 May 2022

Patient’s perspective on their physical well-being can help better predict cancer treatment outcomes

A breast cancer patient’s perspective on their physical well-being can provide a better indication of their response to cancer treatment than clinician-based tools, a new study has found, highlighting the importance of shared decision-making in the treatment process.

26 May 2022

Ketamine uses a previously unknown pathway to produce an antidepressant effect, study finds

For the 280 million people suffering from depression globally, relief cannot come fast enough. Monoaminergic antidepressants, including selective serotonin reuptake inhibitors (SSRIs) take weeks to months to take effect and do not work for more than one in three patients.

26 May 2022

Staying physically active before COVID-19 infection can help reduce disease severity

A consortium of Luxembourgish research institutions studying the national population have been looking to identify factors that may contribute to variations in severity of COVID-19 and its associated symptoms.

26 May 2022

Common type 2 diabetes medication could be the key to improving fertility in women with obesity

Researchers may have found a solution to improving fertility in women with obesity, following a successful trial in mice using diabetes medication to reduce blood glucose levels.

26 May 2022

Size of air pollution particles may affect a person's risk of dying from stroke, study finds

Living in areas with higher air pollution is associated with an increased risk of in-hospital death from stroke, and the risk varies depending on the size of the air pollution particles, according to a new study published in the May 25, 2022, online issue of Neurology, the medical journal of the American Academy of Neurology.

25 May 2022

Study illustrates risk of Omicron infection in fully vaccinated individuals

Scientists studied SARS-CoV-2 humoral responses in a healthy young person who was infected by the Omicron BA.1.15 after receiving booster vaccination.

25 May 2022

Study uncovers a possible mechanism that links cerebrovascular disease and Alzheimer's

For more than 20 years, scientists have known that people with hypertension, diabetes, high cholesterol, or obesity have a higher likelihood of developing Alzheimer's disease.

25 May 2022

The role of pyroptosis in COVID-19

Researchers investigate the mechanisms by which SARS-CoV-2 induces NLRP3 inflammasome formation leading to pyroptosis.

25 May 2022

Longer period of exclusive breastfeeding linked with decreased odds of childhood asthma

Pregnant women and new mothers are often presented with information on the benefits of breastfeeding their infants.

25 May 2022

Robust biomarker panel could help predict gestational diabetes in early pregnancy

UCLA researchers have taken the initial step in identifying what may be an effective way to detect gestational diabetes mellitus (GDM) earlier in pregnancy, potentially improving diagnosis and treatment for what is the most common disorder of pregnancy.

25 May 2022

Study shows potential role for MRI with DWI in surveillance protocols after pancreatic cancer resection

According to ARRS' American Journal of Roentgenology, adding diffusion-weighted MRI (DWI) to conventional MRI improves the differentiation of locally recurrent tumor and post-surgical fibrosis after pancreatic ductal adenocarcinoma (PDAC) resection, primarily due to improved sensitivity for recurrence.

25 May 2022

Key immunological changes that support peanut allergy remission in children discovered

Australian researchers have discovered the key immunological changes that support the remission of peanut allergy in children, paving the way for new, more targeted treatments.

25 May 2022

Medical Research News

Immunogenicity predictions reveal SARS-CoV-2 CD8+ T-cell epitopes

Model predicts scenarios that reveal the benefit of updating COVID vaccines

Mucosal COVID vaccine candidate powerfully protective in macaques

Study shows glomerulonephritis after SARS-CoV-2 mRNA vaccination likely coincidental

SARS-CoV-2 variants BA.4 and BA.5 show substantial immune escape compared with BA.1 and BA.2

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

A 6.4 million genome analysis predicts dominant SARS-CoV-2 variants

Scientists discover a gene defect that results in allergic and autoimmune disease

Patient’s perspective on their physical well-being can help better predict cancer treatment outcomes

Ketamine uses a previously unknown pathway to produce an antidepressant effect, study finds

Staying physically active before COVID-19 infection can help reduce disease severity

Common type 2 diabetes medication could be the key to improving fertility in women with obesity

Size of air pollution particles may affect a person's risk of dying from stroke, study finds

Study illustrates risk of Omicron infection in fully vaccinated individuals

Study uncovers a possible mechanism that links cerebrovascular disease and Alzheimer's

The role of pyroptosis in COVID-19

Longer period of exclusive breastfeeding linked with decreased odds of childhood asthma

Robust biomarker panel could help predict gestational diabetes in early pregnancy

Study shows potential role for MRI with DWI in surveillance protocols after pancreatic cancer resection

Key immunological changes that support peanut allergy remission in children discovered

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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