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Study identifies potential risk factor for aortic aneurysms in Loeys-Dietz syndrome

Studying the cells of people and genetically engineered mice, Johns Hopkins Medicine scientists say they have uncovered a potential reason why patients with Loeys-Dietz syndrome, an inherited connective tissue disorder, are especially prone to developing aneurysms at the root of the aorta, the major artery that carries blood away from the heart and to the rest of the body.

9 Dec 2024

Lab-grown tumor organoids predict patient response to CAR T cell therapy

For the first time, researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM) to accurately model a patient's response to CAR T cell therapy in real time.

9 Dec 2024

Women skip post-stroke medications more often than men, study reveals

Women, especially Mexican Americans, are more likely than men to skip critical post-stroke medications, highlighting the need for targeted interventions to improve adherence and reduce stroke recurrence.

9 Dec 2024

Two new subtypes of MASH revealed with different risks and outcomes

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly referred to as nonalcoholic fatty liver disease (NAFLD), impacts roughly 30% of the global adult population.

9 Dec 2024

Soft tissue sarcoma rates vary between active-duty military servicemen and general population

A recent analysis reveals that the incidence rates of soft tissue sarcomas - cancers in muscle, fat, blood vessels, nerves, and tendons - are lower in young U.S. active-duty military servicemen compared with those in the general population, but higher in middle-aged servicemen, perhaps due to greater cumulative exposure to toxins.

9 Dec 2024

New immunotherapeutic platform improves mRNA therapy efficacy against cancer

Therapeutic mRNAs offer great potential as a versatile and precise tool against cancer and other diseases.

9 Dec 2024

Post-COVID health risks: Obesity fuels sequelae, smoking hits memory

Obesity significantly increases the risk of post-COVID-19 long-term sequelae, while smoking is primarily linked to memory disorders but does not raise the risk of long COVID symptoms or hospitalization.

9 Dec 2024

Minoxidil found safe and effective for hair loss in breast cancer patients

Hair loss during chemotherapy can cause enough distress for some women to lose self-confidence, which experts say may discourage them from seeking chemotherapy in the first place.

9 Dec 2024

Mouse study links glyphosate to Alzheimer's-like brain changes and anxiety

Glyphosate exposure in mice exacerbates Alzheimer's-like neuropathologies, increases neuroinflammation, and leaves lasting effects, even after prolonged recovery.

9 Dec 2024

Unprocessed red meat and weight loss: Is it a healthy choice?

Unprocessed red meat can be part of a healthy weight maintenance diet after rapid weight loss, with no adverse effects on metabolism or cardiovascular health. This study finds similar outcomes with diets including 25g or 150g of red meat daily.

9 Dec 2024

X-chromosome study reveals hidden genetic links to Alzheimer’s disease

A groundbreaking study explores the overlooked X-chromosome’s role in Alzheimer’s disease, revealing seven genetic loci linked to neurodegenerative decline and cognitive reserve.

9 Dec 2024

Study finds divergent relationship between different sugar sources and cardiovascular disease risk

A little of what you fancy does you good… unless it's a fizzy drink. Scientists studying the impact of sugar on the risk of cardiovascular disease have found that eating too much added sugar increases your risk of stroke or aneurysm, but eating a few treats is associated with a lower risk of cardiovascular diseases.

9 Dec 2024

CHOP study shows safety of rotavirus vaccine in neonatal intensive care unit

Researchers from Children's Hospital of Philadelphia (CHOP) found that transmission of rotavirus vaccine strains in a neonatal intensive care unit (NICU) is rare and without clinical consequences, strongly suggesting that giving the rotavirus vaccine to eligible infants during their hospitalization provides immune benefits that outweigh any risks.

9 Dec 2024

Healthy diet can help reduce the severity of chronic pain

Chronic pain is an acute and debilitating condition that affects millions of people worldwide. And while pain interventions are available, many people struggle without treatment at all.

9 Dec 2024

Simple dietary supplement may provide new approach to boost CAR T cell cancer-fighting power

A simple dietary supplement may provide a new approach to boost CAR T cell function, according to a study from researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

9 Dec 2024

Hospital-acquired pressure ulcers may hinder neurological recovery in spinal cord injury patients

Research led by The Ohio State University Wexner Medical Center and College of Medicine along with scientists at the Charité – Universitätsmedizin Berlin in Berlin, Germany, provides first evidence that hospital-acquired pressure ulcers are a potent risk factor for poor neurological recovery among patients with acute spinal cord injury (SCI).

9 Dec 2024