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Exploring the potential of MSCs in cancer therapy

A new review was published in Oncotarget's Volume 15 on November 22, 2024, entitled "Mesenchymal stem cells – the secret agents of cancer immunotherapy: Promises, challenges, and surprising twists."

4 Dec 2024

Disrupted sleep-wake rhythms linked to liver disease progression

The prevalence of MASLD (metabolic dysfunction-associated steatotic liver disease) is exploding in most regions of the world, boosted by increased obesity and sedentary lifestyles. MASLD (formerly known as non-alcoholic fatty liver disease) is already the most common liver disorder: it affects 30% of adults and between 7% and 14% of children and adolescents, and this prevalence is predicted to rise to more than 55% of adults by 2040.

4 Dec 2024

US census data reveal socioeconomic drivers of air pollution-related cancer risks

New research builds on scientific understanding of how air pollution and cancer risk are distributed throughout the U.S. Air pollution, often resulting from industrial or vehicle emissions, can travel for hundreds of miles and impact the health of communities through higher rates of asthma, respiratory infections, stroke, and lung cancer.

4 Dec 2024

Study highlights gaps in current health programs for truck drivers

It might seem out of place on the side of a highway, but purpose-built exercise equipment installed at truck stops across Australia could be just the thing to encourage truck drivers to take a break and take control of their health and wellbeing.

4 Dec 2024

Spider brain studies lead to breakthrough in understanding human brain diseases

Researchers from Saint Michael's College and the University of Vermont have made a groundbreaking new discovery that provides a better understanding of how Alzheimer's disease develops in the human brain.

4 Dec 2024

AI in medicine: Revolutionary tools, uncertain results

AI decision-making systems show promise but lack consistent evidence for improving patient-relevant outcomes like mortality and quality of life. Rigorous harm-benefit assessments and transparency are needed for safe integration into healthcare.

3 Dec 2024

Type 2 diabetes doubles infection-related mortality and exposes gaps in health reporting

People with type 2 diabetes face a significantly higher risk of infection-related deaths, particularly in younger age groups, with infections accounting for 13% of deaths compared to 1.2% in conventional records.

3 Dec 2024

Dual use of vapes and cigarettes hinders smoking cessation

People who use both vapes and cigarettes are less likely to quit compared to people who only smoke or only vape, according to a study published today (Wednesday) in ERJ Open Research.

3 Dec 2024

Holistic lifestyle interventions outshine drugs in preventing cardiometabolic diseases

Comprehensive lifestyle interventions prevent cardiometabolic diseases effectively but face challenges in routine care and require supportive policies for lasting impact.

3 Dec 2024

Study shows lasting benefits of anti-hormonal therapy in postmenopausal women

Today, women with estrogen-sensitive breast cancer receive anti-hormonal therapy. Researchers now show that postmenopausal women with low-risk tumors have a long-term benefit for at least 20 years, while the benefit was more short-term for younger women with similar tumor characteristics who had not yet gone through the menopause.

3 Dec 2024

Short bursts of vigorous activity may lower cardiovascular risk in women

Short bursts of incidental vigorous physical exertion, lasting less than a minute each, may almost halve the risk of a major cardiovascular event, such as heart attack or heart failure among women who don't exercise regularly, finds research published online in the British Journal of Sports Medicine.

3 Dec 2024

Behavioral chaos in Alzheimer’s disease mice decoded by machine learning

Researchers use machine learning to identify behavioral disruptions in Alzheimer’s disease mouse models, highlighting a potential therapeutic target in fibrinogen-microglia interactions.

3 Dec 2024

Upcoding practices by hospitals lead to billions in extra payments

In five states over nearly a decade, hospitals have increased how frequently they document patients as needing the highest intensity care, which has led to hospitals receiving billions in extra payments from health plans and government programs, according to a new RAND study.

3 Dec 2024

Human ability to process numbers traced to unexpected brain region

New research reveals the unique human ability to conceptualize numbers may be rooted deep within the brain.

3 Dec 2024

Serum protein panel test can help identify cardiomyopathy risk in childhood cancer survivors

Early disease detection is beneficial for securing the best possible outcomes for patients. But finding noninvasive, effective ways to predict disease risk is a tremendous challenge.

3 Dec 2024

Study reveals vast majority of U.S. states experiencing decline in drugstores

About 1 in 3 U.S. retail pharmacies have closed since 2010, with the vast majority of states experiencing an overall decline in drugstores in recent years, according to a new study from researchers at USC and the University of California, Berkeley.

3 Dec 2024

Study cracks the cold case of immunotherapy resistance

A study from the University of Michigan Health Rogel Cancer Center may have, at last, cracked the cold case of immunotherapy resistance.

3 Dec 2024

Spinal manipulation linked to lower butalbital use in tension-type headaches

A team of researchers led by University Hospitals Connor Whole Health have identified an association between spinal manipulative therapy (SMT) and a reduced likelihood of butalbital prescription and medication overuse headache (MOH) for patients experiencing tension-type headaches (TTH). Their retrospective study, published in Health Science Reports, includes more than 6,200 patients from a national US database spanning 2013 to 2024.

3 Dec 2024

New immune therapy improves survival and reduces tumor burden in glioblastoma

The Wistar Institute's David B. Weiner, Ph.D. - Executive Vice President, director of the Vaccine & Immunotherapy Center and W.W. Smith Charitable Trust Distinguished Professor in Cancer Research - and his lab have successfully tested a new immune therapy that, in preclinical lab testing, reliably improves survival and reduces tumor burden in glioblastoma.

3 Dec 2024