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Lifestyle choices and cognitive health linked to future dementia risk

The risk of developing dementia later in life is strongly predicted by a person's cognitive ability, functional limitations and physical health as many as 20 years before onset of the illness, according to a new RAND report.

3 Dec 2024

Skeletal muscle loss linked to increased risk of dementia

Skeletal muscle loss is a risk factor for developing dementia, according to a study being presented today at the annual meeting of the Radiological Society of North America (RSNA).

3 Dec 2024

Research sheds light on how mutated PSEN2 accelerates familial Alzheimer's disease progression

Alzheimer's disease is a debilitating condition that slowly robs people of their memory and cognitive abilities, affecting millions of people worldwide.

3 Dec 2024

Brain scan could predict success of spinal surgery for chronic pain

A 10-minute brain scan can predict the effectiveness of a risky spinal surgery to alleviate intractable pain. The Kobe University result gives doctors a much-needed biomarker to discuss with patients considering spinal cord stimulation.

3 Dec 2024

Study links menopause hormone therapy to varied heart and blood clot risks

Research on hormone therapy reveals critical insights into cardiovascular disease risks, guiding clinicians in selecting safer treatment options for menopause.

3 Dec 2024

Orbit Discovery and Evergreen Theragnostics expand research collaboration to advance targeted therapeutics development

Orbit Discovery, a leading provider of peptide discovery services, and Evergreen Theragnostics, a radiopharmaceutical company at the forefront of precision medicine, today announced an extension to their research collaboration to find novel targeting peptides for radiopharmaceutical delivery.

From Orbit Discovery 3 Dec 2024

Key risk factors influencing mortality rates in chronic pulmonary aspergillosis patients

A systematic review reveals chronic pulmonary aspergillosis mortality is driven by age and underlying conditions, highlighting the need for targeted therapies.

3 Dec 2024

Peptidomimetics as a new strategy to modulate Aurora-A and combat cancer

A new approach to targeting a protein involved in cell division, which can misfunction in cancer, has revealed new insights into how it functions.

3 Dec 2024

Biocompatible liquid ink enables scalp-printed electrodes for non-invasive EEG

For the first time, scientists have invented a liquid ink that doctors can print onto a patient's scalp to measure brain activity. The technology, presented December 2 in the Cell Press journal Cell Biomaterials, offers a promising alternative to the cumbersome process currently used for monitoring brainwaves and diagnosing neurological conditions. It also has the potential to enhance non-invasive brain-computer interface applications.

3 Dec 2024

A roadmap for improving cancer care in South Asia

A series of five papers, published today in The Lancet Oncology by a University of Pittsburgh-led international team, highlights critical public health challenges related to cancer control in the eight countries that form the South Asian Association for Regional Cooperation (SAARC) and the Rohingya refugee population in Bangladesh.

3 Dec 2024

Overcoming challenges in developing cell therapies for heart disease

Pathways to new treatments for heart failure take time - as long as four decades for two now accepted therapies. So, new attempts to repair scar tissue in infarcted hearts using cells or cell products need more time to develop clinical therapies that can reduce risk of death from heart failure after a heart attack.

3 Dec 2024

Fas-p53 pathway drives metabolic dysfunction and obesity-linked insulin resistance

Researchers unveil Fas-p53 axis as a key regulator in adipocyte metabolism, linking it to obesity and insulin sensitivity through energy expenditure and inflammation pathways.

3 Dec 2024

Greening cities saves lives and transforms urban health

Increasing urban green spaces in Italy could prevent 28,433 deaths annually, highlighting their critical role in reducing mortality and improving public health.

2 Dec 2024

New food-grade natural solution created for tackling obesity

As obesity rates continue to rise, many are turning to prescription medicines like Ozempic for weight loss. But with significant side effects, accessibility and cost issues, alternatives are needed.

2 Dec 2024

Short sleep and high blood pressure may increase brain damage

People with high blood pressure who also lack sleep may be at increased risk of reduced cognitive performance and greater brain injury, Monash University research has found.

2 Dec 2024

From potential to practice: A blueprint for responsible AI in healthcare

Researchers developed comprehensive AI guidelines to ensure safe, equitable, and effective integration into healthcare, with a case study highlighting ambient documentation applications.

2 Dec 2024

Disrupted sleep patterns identified in patients with metabolic dysfunction-associated steatotic liver disease

The prevalence of MASLD (metabolic dysfunction-associated steatotic liver disease) is exploding in most regions of the world, boosted by increased obesity and sedentary lifestyles.

2 Dec 2024

Low levels of arsenic exposure linked to increased kidney cancer risk

New research findings from the Texas A&M University School of Public Health indicate that exposure to even low levels of arsenic poses significant health risks, including an increased risk of kidney cancer.

2 Dec 2024

New algorithm identifies cells responsible for aggressive tumor growth

Cancer Research UK-funded scientists have unveiled the first computational algorithm capable of identifying which cell populations within a tumor drive aggressive growth.

2 Dec 2024

Text message reminders fail to boost long-term medication adherence

A new study published today in JAMA reveals text message reminders for patients who delay refilling their medications didn't help improve how regularly they refilled medications over a year.

2 Dec 2024