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Researchers discover new cause of cytokine storm in COVID-19

As part of the COVID-19 International Research Team, researchers at the Johns Hopkins Kimmel Cancer Center, Children's Hospital of Philadelphia, the University of Pittsburgh and Weill Cornell Medicine discovered a novel cause of cytokine storm - the extreme inflammatory response associated with increased risk of death in COVID-19 infection.

2 Dec 2024

Alcohol consumption raises pain threshold and aggressive behavior

Alcohol's ability to increase people's pain threshold is one reason that drinking also leads to more aggressive behavior, a new study suggests.

2 Dec 2024

Study highlights the critical role of TLR7 in sex-biased Alzheimer’s-related demyelination

Inhibiting an immune signaling protein called TLR7 may help preserve the protective layer surrounding nerve fibers in the brain during both Alzheimer's disease and ordinary aging, suggests a study led by researchers at Weill Cornell Medicine.

2 Dec 2024

Boosting endocannabinoids could reduce opioid addiction risk

Increasing the levels of chemicals naturally produced in the body called endocannabinoids may thwart the highly addictive nature of opioids such as morphine and oxycodone while maintaining the drugs' ability to relieve pain, according to Weill Cornell Medicine investigators working with researchers from The Center for Youth Mental Health at NewYork-Presbyterian.

2 Dec 2024

New study explores heart risks of cancer immunotherapy

A cancer therapy that prompts the body's immune defenses against viruses and bacteria to attack tumors can make patients more vulnerable to heart attack and stroke.

2 Dec 2024

Beta-blocker drugs may slow Huntington's disease progression

A common heart drug may slow the progression of Huntington's disease (HD), according to a new study by University of Iowa Health Care researchers.

2 Dec 2024

Women with premature ovarian insufficiency face higher risk of autoimmune diseases

Research reveals a significant association between premature ovarian insufficiency and autoimmune diseases, highlighting hypothyroidism as a common condition.

2 Dec 2024

Minority genetic variation in tuberculosis offers new insights for improving outbreak tracking

Findings show that within-host MTBC variation improves transmission inference, suggesting new strategies for understanding and controlling tuberculosis spread.

2 Dec 2024

New study explores obecabtagene autoleucel for adults with hard-to-treat leukemia

FELIX study results reveal obe-cel's potential in relapsed B-cell ALL, achieving 77% remission with low severe toxicity, enhancing CAR T-cell therapy outcomes.

2 Dec 2024

Visceral fat found to contribute to Alzheimer's disease development

Researchers have linked a specific type of body fat to the abnormal proteins in the brain that are hallmarks of Alzheimer's disease up to 20 years before the earliest symptoms of dementia appear, according to a study being presented today at the annual meeting of the Radiological Society of North America (RSNA).

2 Dec 2024

Engineered stone countertop workers at risk for silicosis

Durable and attractive, engineered stone countertops are a popular feature in modern American kitchens, but the workers who build them are risking their health.

2 Dec 2024

Natural proteins may offer new way to treat covid-19 and autoimmune disorders

Some people naturally have higher levels of proteins that protect them from covid-19. New studies at Umeå University of our immune system may pave the way for more personalized treatments of both covid-19 and autoimmune disorders.

2 Dec 2024

Higher plant-based protein intake linked to lower heart disease risk

Eating a diet with a higher ratio of plant-based protein to animal-based protein may reduce the risk of cardiovascular disease (CVD) and coronary heart disease (CHD), according to a new study led by researchers at Harvard T.H. Chan School of Public Health.

2 Dec 2024

Lung cancer screening with CT can identify coronary artery calcium

Lung cancer screening with low-dose chest computed tomography (CT) may detect more than just lung cancer. As new research in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.231602 shows, these CTs can identify coronary artery calcium, a strong risk factor for coronary artery disease (CAD), in patients without cardiac symptoms.

2 Dec 2024

ARMC5 regulates saturated and unsaturated fatty acid levels in fat cells

Researchers at Osaka University identified a degradation factor for SREBP1 as essential for maintaining the balance of saturated and unsaturated fatty acids in adipose tissue.

2 Dec 2024

Gut transit time and pH shape microbiome individuality and dietary responses

Scientists reveal gut transit time and pH as key drivers of microbiome and metabolic individuality, paving the way for personalized dietary strategies.

1 Dec 2024

Can beef fit in a heart-healthy diet? Review provides new insights

A systematic review suggests unprocessed beef has minimal impact on cardiovascular health markers.

1 Dec 2024

Heart health benefits soar with regular sleep schedules, research finds

Irregular sleep patterns significantly increase the risk of major adverse cardiovascular events (MACE), with higher sleep regularity associated with reduced cardiovascular risks. This large UK Biobank study underscores the need to prioritize sleep regularity in public health and clinical guidelines.

1 Dec 2024

Men face sharper brain aging from obesity and heart risks

Obesity and cardiovascular risk factors accelerate brain volume loss, with males experiencing earlier and more significant impacts, highlighting the importance of early interventions to prevent neurodegeneration.

1 Dec 2024

Capsule sponge test revolutionizes GERD diagnosis, reduces unnecessary endoscopies

Capsule sponge testing, a minimally invasive diagnostic tool, effectively triages gastroesophageal reflux disease (GERD) patients, reducing unnecessary endoscopies by 70% and accurately identifying high-risk cases for Barrett’s esophagus and cancer in real-world clinical settings.

1 Dec 2024