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New method provides accurate measurement of drug permeability across the blood-brain barrier

For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the blood-brain barrier, a compact layer of cells that protect the brain from potentially dangerous substances and microbes.

11 Feb 2025

Targeted polymersomes boost methotrexate efficacy for aggressive choriocarcinoma treatment

Researchers develop targeted polymersomes loaded with methotrexate for the treatment of gestational choriocarcinoma,

11 Feb 2025

Changes to intermediate filament protein drive aggressive breast cancer growth

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner.

11 Feb 2025

New mechanism of immune evasion discovered in cancer cells

The immune system plays a key role in detecting and destroying cancer cells. Cancer immunotherapy works by programming immune cells to recognize and eliminate cancer cells.

11 Feb 2025

Novel biomarker for early prevention of Alzheimer’s disease

New serine biomarkers show promise for early Alzheimer's detection, linking tau assemblies to cognitive decline and offering potential for timely intervention.

11 Feb 2025

Severe infections linked to increased risk of heart failure

Findings highlight the importance of infection prevention measures and personalized heart failure care.

11 Feb 2025

Single dose of antibody shields macaques from severe H5N1 influenza

National Institutes of Health (NIH) scientists and their colleagues report that a single dose of a broadly neutralizing antibody (bnAb) administered prior to virus exposure protects macaques from severe H5N1 avian influenza.

11 Feb 2025

Study shows improvement in disability-free life for older Americans

A sizeable improvement was found in the prevalence of American adults aged 65 and older without disabilities -- including memory, hearing, visual, and functional disabilities or limitations in activities of daily living -- according to a new nationally representative study published online in the Archives of Gerontology and Geriatrics Plus found.

11 Feb 2025

Study uncovers a significant presence of manic symptoms in schizophrenia patients

In a notable Genomic Press research report, researchers at the Aristotle University of Thessaloniki have uncovered a significant presence of manic symptoms in patients with schizophrenia spectrum disorders (SSDs), offering valuable insights that could reshape treatment approaches.

11 Feb 2025

Childhood physical activity can prevent tobacco smoking in adolescence

Teenagers may be less likely to initiate tobacco smoking if they engage in moderate-to-vigorous physical activity (MVPA) from childhood, a new study conducted in collaboration between the Universities of Bristol and Exeter in the UK, and the University of Eastern Finland shows.

11 Feb 2025

Yoga can reduce stress in both schools and workplaces

Ten years of research on yoga as a stress-reducing activity provides a clear answer: A little effort offers real health benefits.

11 Feb 2025

Adverse pregnancy outcomes increase cardiovascular risk, even in unaffected sisters

A study reveals that women with adverse pregnancy outcomes and their APO-free sisters share elevated cardiovascular disease risks, indicating genetic links.

11 Feb 2025

Trust and risk perception influence brain activity in health assessments

Perceiving whether another person is a personal health risk requires quickly assessing their trustworthiness.

11 Feb 2025

Climate change may increase the risk of prolonged pregnancy

New Curtin University research has found exposure to outdoor air pollution and extreme temperatures during pregnancy may increase the risk of prolonged pregnancy, offering new insights into the impact of climate change on maternal health.

11 Feb 2025

Daily fruit and vegetable extracts may boost brain power

A study reveals polyphenol-rich nutraceuticals enhance cognitive performance and boost neuroprotective biomarkers, offering a dietary approach to brain health.

11 Feb 2025

Light-activated therapy reduces antibiotic resistance in Staphylococcus aureus

Photodynamic inactivation using curcumin shows promise in reducing antibiotic resistance diversity in Staphylococcus aureus, enhancing treatment effectiveness.

11 Feb 2025

Adrenomedullin hormone as key driver of insulin resistance in obesity-linked type 2 diabetes

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.

11 Feb 2025

Yale rewrites genetic code for new proteins

Synthetic biologists from Yale were able to re-write the genetic code of an organism - a novel genomically recoded organism (GRO) with one stop codon - using a cellular platform that they developed enabling the production of new classes of synthetic proteins. These synthetic proteins, researchers say, offer the promise of innumerable medical and industrial applications that can benefit society and human health.

11 Feb 2025

Mental health drives med student dropout rate

Around 1 in 5 UK medical students considers dropping out of medical school, with mental health issues a key contributor to their intention to abandon medicine, suggest the results of an observational study published in the open access journal BMJ Open.

11 Feb 2025

Persistent social and cognitive difficulties linked to poor GCSE results

The combination of poorly developed social and cognitive skills during childhood is linked to poor exam results by the age of 16, with those for whom these issues persist throughout their childhood more than 4 times as likely not to pass at least 5 GCSEs, finds research published online in the Archives of Disease in Childhood.

11 Feb 2025