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Combination of nanoscale topography and triculture technology benefits large or slow-healing wounds

Large or slow-healing wounds that do not receive adequate blood flow could benefit from a novel approach that combines a nanoscale graft onto which three different cell types are layered. Proper cell alignment on the nanograft allows for the formation of new blood vessel-like structures, as reported in of Tissue Engineering, Part A, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free for download on the Tissue Engineering website until May 26, 2016.

27 Apr 2016

Researchers test potential positive effects of micro-injury in mice modeled with AD

Researchers testing the potential positive effects of "micro-injury" by brief insertion of a small needle into the hippocampal region of mice modeled with Alzheimer's disease (AD) have found that the procedure not only stimulated the hippocampus into regenerative activity, but also reduced β-amyloid plaques, a hallmark of AD.

27 Apr 2016

ATR-FTIR spectroscopy could be effective for detecting ulcerative colitis

A minimally invasive screening for ulcerative colitis, a debilitating gastrointestinal tract disorder, using emerging infrared technology could be a rapid and cost-effective method for detecting disease that eliminates the need for biopsies and intrusive testing of the human body, according to researchers at Georgia State University.

27 Apr 2016

First small molecule targeted therapy holds promise for Usher syndrome

Usher syndrome (USH) is characterized by hearing loss or deafness at birth and progressive vision loss, and is the most common cause of inherited dual sensory deficit. No treatment is currently available to stop or slow the progression of vision or hearing loss in USH3, one of three clinical classifications for USH that are further divided into subtypes and all associated with different genes.

27 Apr 2016

Newly discovered hybrid house mosquitoes could be bridge vectors between birds and humans

The team of researchers from the Institute of Parasitology at Vetmeduni Vienna sampled nearly 1,500 house mosquitoes in eastern Austria. The northern house mosquito Culex pipiens, representing more than 90% of the total catch, was the most abundant. Culex pipiens comprises a complex of ecologically different forms that are morphologically indistinct.

27 Apr 2016

OSMR gene plays key role in driving growth of glioblastoma tumors

Glioblastoma is the most aggressive type of brain tumor in adults. Unfortunately, there are no effective treatments for the disease. On average, patients succumb just 16 months after diagnosis.

27 Apr 2016

First-ever vaccine to combat Leishmaniasis under development

As scientists scramble to get a Zika virus vaccine into human trials by the end of the summer, a team of researchers is working on the first-ever vaccine to prevent another insect-borne disease - Leishmaniasis - from gaining a similar foothold in the Americas.

27 Apr 2016

Series of routine tests may not be beneficial to patients with age-related disorder

A series of tests physicians routinely order to help diagnose and follow their patients with an elevated antibody level that is a marker for cancer risk, often do not benefit the patient but do increase health care costs, pathologists report.

27 Apr 2016

Endocrine Society urges physicians to increase screening for primary aldosteronism

The Endocrine Society today issued a Clinical Practice Guideline calling on physicians to ramp up screening for primary aldosteronism, a common cause of high blood pressure.

27 Apr 2016

Cholesterol-lowering drugs may not reduce colorectal cancer risk

Long-term use of the cholesterol-lowering drugs known as statins does not appear to decrease a patient's risk of colorectal cancer, suggests a new, large case-control study from Penn Medicine researchers published this week in PLOS Medicine.

27 Apr 2016

Understanding need for supplemental cancer screening for women with dense breasts

In a study appearing in the April 26 issue of JAMA, Elizabeth A. Rafferty, M.D., formerly of Massachusetts General Hospital, Boston, and colleagues evaluated the screening performance of digital mammography combined with tomosynthesis (a type of imaging) compared with digital mammography alone for women with varying levels of breast density.

27 Apr 2016

Innovations in pre-clinical MRI: an interview with Priv. Doz. Dr. Dominik von Elverfeldt

To me the most exciting aspect of pre-clinical imaging is its broad range, from very basic science up to applied science. You deal with a range of disciplines including biology, chemistry, physics, biochemistry, biophysics, cell biology and of course medicine, as the aim is the translation of research to humans.

From Bruker BioSpin - NMR, EPR and Imaging 27 Apr 2016

Updated guidance on botulinum toxin formulations for four indications

The American Academy of Neurology has issued an update to its 2008 guidelines on the use of botulinum toxin for the treatment of spasticity, cervical dystonia, blepharospasm and migraine headache.

27 Apr 2016

Researchers discover gene that plays vital role in inherited eye disorder

Researchers from the University of Liverpool have identified a specific gene that plays a key role in an inherited eye disorder.

26 Apr 2016

Research focuses on alcohol-induced blackouts

Alcohol-induced blackouts, defined as memory loss of all or a portion of events that occurred during a drinking episode, are reported by approximately 50 percent of drinkers, and are associated with a wide range of negative consequences, including injury and death.

26 Apr 2016

New national database could help identify major influences on miscarriage

A new national database could help relieve the misery of miscarriage for thousands of women.

26 Apr 2016

Newly published manuscripts enhance understanding of the immune system

MedImmune, the global biologics research and development arm of AstraZeneca, today announced that it has achieved a significant scientific milestone by publishing three manuscripts in Nature Immunology that advance the understanding of the immune system and highlight underlying mechanisms in two little-understood disease areas -- chronic obstructive pulmonary disease (COPD) and systemic lupus erythematosus (SLE).

26 Apr 2016

Zinc sparks help doctors choose best eggs to transfer during IVF

A stunning explosion of zinc fireworks occurs when a human egg is activated by a sperm enzyme, and the size of these "sparks" is a direct measure of the quality of the egg and its ability to develop into an embryo, according to new research from Northwestern Medicine.

26 Apr 2016

UAB receives $2.86 million NIH grant to study effectiveness of cognitive training in older adults with HAND

University of Alabama at Birmingham School of Nursing Professor David Vance, Ph.D., has received a five-year, $2.86 million R01 grant from the National Institute of Mental Health for a study to determine whether quality of life of middle-aged and older adults with HIV can be improved by enhancing cognitive functioning through speed of processing training.

26 Apr 2016

Clinical inertia puts Type 2 diabetes patients at further risk of preventable complications

People with Type 2 diabetes are being 'let down' because they are being forced to wait for further treatment when needed.

26 Apr 2016

Medical Research News

Combination of nanoscale topography and triculture technology benefits large or slow-healing wounds

Researchers test potential positive effects of micro-injury in mice modeled with AD

ATR-FTIR spectroscopy could be effective for detecting ulcerative colitis

First small molecule targeted therapy holds promise for Usher syndrome

Newly discovered hybrid house mosquitoes could be bridge vectors between birds and humans

OSMR gene plays key role in driving growth of glioblastoma tumors

First-ever vaccine to combat Leishmaniasis under development

Series of routine tests may not be beneficial to patients with age-related disorder

Endocrine Society urges physicians to increase screening for primary aldosteronism

Cholesterol-lowering drugs may not reduce colorectal cancer risk

Understanding need for supplemental cancer screening for women with dense breasts

Innovations in pre-clinical MRI: an interview with Priv. Doz. Dr. Dominik von Elverfeldt

Updated guidance on botulinum toxin formulations for four indications

Researchers discover gene that plays vital role in inherited eye disorder

Research focuses on alcohol-induced blackouts

New national database could help identify major influences on miscarriage

Newly published manuscripts enhance understanding of the immune system

Zinc sparks help doctors choose best eggs to transfer during IVF

UAB receives $2.86 million NIH grant to study effectiveness of cognitive training in older adults with HAND

Clinical inertia puts Type 2 diabetes patients at further risk of preventable complications

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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