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Breakthrough drug improves treatment of medulloblastoma in mice

Brain cancer is the second-leading cause of death in children in the developed world. For the children who survive, standard treatments have long-term impacts on their development and quality of life, particularly in small children and infants.

4 Feb 2025

Topical ABT-263 treatment improves wound healing in aging skin

A new research paper was published by Aging (Aging-US) on December 3, 2024, in Volume 17, Issue 1, titled "Topical ABT-263 treatment reduces aged skin senescence and improves subsequent wound healing."

4 Feb 2025

SARS-CoV-2 infection linked to rapid plaque growth in coronary arteries

A new study found severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was associated with the rapid growth of plaque in the coronary arteries and an increased risk of cardiovascular events.

4 Feb 2025

New insights into PTSD's genetic architecture unveiled by Dr. Kerry Ressler

In a comprehensive Genomic Press Interview, Dr. Kerry Ressler, Chief Scientific Officer at McLean Hospital and Professor of Psychiatry at Harvard Medical School, unveils groundbreaking advances in understanding the neurobiological basis of post-traumatic stress disorder (PTSD) and related anxiety conditions.

4 Feb 2025

Asthma and antibiotic use increase the likelihood of revision sinus surgery

The probability of revision sinus surgery including the removal of nasal polyps is higher if the patient has asthma or is on antibiotics at the time of their initial surgery. However, higher age was not a predictor of revision surgery, according to a new study.

4 Feb 2025

Maternal stress may leave epigenetic marks on certain placental genes

Maternal stress could leave epigenetic imprints on genes in the placenta associated with cortisol — a necessary hormone for fetal development — and this would affect the baby's development from very early stages, as stated in a paper published in the journal European Neuropsychopharmacology.

4 Feb 2025

Yo-yo dieting found to harm kidney health in type 1 diabetes patients

Body-weight cycling (also known as yo-yo dieting) has been shown to significantly increase the risk of kidney disease in people with type 1 diabetes, regardless of body mass index (BMI) and other traditional risk factors, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

4 Feb 2025

High discontinuation rates of GLP-1 agonists found among patients with obesity

Discontinuation of GLP-1 receptor agonists in obesity is common, driven by weight regain and socioeconomic factors, impacting treatment effectiveness.

4 Feb 2025

Engineered fat cells starve tumors and prevent cancer growth

Scientists transformed energy-storing white fat cells into calorie-burning 'beige' fat. Once implanted, they outcompeted tumors for resources, beating back five different types of cancer in lab experiments.

4 Feb 2025

New discovery offers hope for stopping childhood brain tumors before they start

Scientists at The Hospital for Sick Children (SickKids) have discovered a way to stop tumour growth before it starts for a subtype of medulloblastoma, the most common childhood malignant brain cancer.

4 Feb 2025

Blocking a protein could halt the growth of fast-growing cancers

Preventing the cell's protein factories from making the notorious cancer-causing protein MYC could stop out-of-control tumors.

4 Feb 2025

Study: A quarter of children in England receive social care services before 18

A quarter of all children in England receive services from children's social care before turning 18, finds a new study by UCL researchers.

4 Feb 2025

New gene therapy shows promise for lifelong treatment of hypophosphatasia

For the last 10 years, the only effective treatment for hypophosphatasia (HPP) has been an enzyme replacement therapy that must be delivered by injection three-to-six times each week.

4 Feb 2025

Traffic delays increase fast food visits and unhealthy eating habits

Ever notice how much more tempting it is to pick up fast food for dinner after being stuck in traffic? It's not just you. New University of Illinois Urbana-Champaign research shows that traffic delays significantly increase visits to fast food restaurants, leading to unhealthier eating for millions each year.

4 Feb 2025

WSU scientists create genetically engineered mice to study cellular aging

Washington State University scientists have created genetically-engineered mice that could help accelerate anti-aging research.

4 Feb 2025

Omega-3 fatty acids and vitamin D slow biological aging in older adults

Many people would like to delay or even stop the aging process. Previous clinical studies have shown that a reduced calorie intake can slow down the aging process in humans.

4 Feb 2025

Epidemiological study of pulmonary tuberculosis in China over six years

Announcing a new article publication for Zoonoses journal. This study was aimed at exploring pulmonary tuberculosis (PTB) epidemiological characteristics and trends in China from 2016 to 2022, to provide evidence for optimizing strategies and measures for tuberculosis prevention and control.

4 Feb 2025

In silico docking of clinically approved drugs against the SARS-CoV-2 receptor-binding domain

Announcing a new article publication for BIO Integration journal. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in China in December 2019, rapidly spread worldwide, resulting in the coronavirus disease 2019 (COVID-19) pandemic.

4 Feb 2025

Lactate dehydrogenase activity in rat tissues under intermittent hypobaric hypoxia

Announcing a new article publication for BIO Integration journal. As altitude increases, the partial pressure of oxygen will decrease and cause hypobaric hypoxia conditions.

4 Feb 2025

Ultra-processed foods linked to increased obesity risk in preschoolers

Ultraprocessed food consumption in preschoolers is associated with increased body fat, particularly in boys, underscoring the importance of nutrition education.

4 Feb 2025