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Researchers develop tool to measure biological age in individual cell types

A new priority research paper, featured as the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 22, was published on December 29, 2024. The paper is titled "Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution."

2 Jan 2025

New artificial muscle mimics natural tissue with high elasticity and toughness

The study, led by Dr. Cheng-Hui Li from the School of Chemistry and Chemical Engineering, Nanjing University, and Dr. Pengfei Zheng from the Children's Hospital of Nanjing Medical University, successfully developed an artificial muscle with mechanical properties similar to natural muscle tissue.

2 Jan 2025

Histone markers predict human age with accuracy comparable to DNA methylation clocks

Researchers unveil histone-based age predictors, offering a new window into epigenetic aging and its shared patterns across tissues.

2 Jan 2025

New insights into tristetraprolin's impact on basophil-mediated allergic inflammation

Inflammation is a crucial part of the body's defense mechanism, playing a key role in fighting infections and repairing tissue damage.

2 Jan 2025

Psilocybin shows potential for treating mental health disorders in people with cancer and addiction

One or two doses of psilocybin, a compound found in psychedelic mushrooms, may improve the mental health of cancer patients when accompanied by psychotherapy, a new report suggests.

2 Jan 2025

New protein offers hope for heart regeneration

Researchers from the Bakkers group at the Hubrecht Institute have successfully repaired damaged mouse hearts using a protein from zebrafish.

2 Jan 2025

Observational studies overestimate smoking's impact on CKD risk

A recent study published in Health Data Science led by Zhilong Zhang from the Institute of Medical Technology at Peking University Health Science Center and Professor Luxia Zhang from the National Institute of Health Data Science at Peking University has shed light on the complex relationship between smoking behavior and chronic kidney disease (CKD).

2 Jan 2025

Brain mapping reveals cell-specific aging patterns

Based on new brain mapping research funded by the National Institutes of Health (NIH), scientists have discovered that not all cell types in the brain age in the same way.

1 Jan 2025

Pupil changes play key role in memory formation

Cornell University researchers have found the pupil is key to understanding how, and when, the brain forms strong, long-lasting memories.

1 Jan 2025

Study uncovers aspartate's surprising role in lung metastases

Researchers from the lab of Prof. Sarah-Maria Fendt (VIB-KU Leuven) and colleagues have uncovered that the availability of the amino acid aspartate is one reason why the lung is a frequent organ of metastasis.

1 Jan 2025

Scientists pinpoint regions and species fueling coronavirus evolution in bats

Study uncovers the evolution, transmission, and geographic spread of bat coronaviruses in China, revealing key insights into hotspots and the origins of SARS-CoV-2.

1 Jan 2025

$10,000 experiment uncovers what makes us happiest

People across diverse countries experienced greater happiness by spending on others, experiences, and personal growth, with cultural and economic contexts shaping the emotional impact of spending choices.

1 Jan 2025

Machine learning reveals how metabolite profiles predict aging and health

Researchers developed metabolomic aging clocks using machine learning, uncovering links between metabolite profiles, health outcomes, and lifespan.

1 Jan 2025

Plant-based diets made easier for seniors with innovative tech

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1 Jan 2025

Heated mittens show promise in easing osteoarthritis pain and stiffness

A study assessed heated mittens for hand osteoarthritis, finding significant reductions in pain and stiffness but no improvement in hand function. Further long-term studies are needed to clarify their therapeutic potential.

1 Jan 2025

Lithocholic acid enhances health and lifespan, mimicking calorie restriction

Lithocholic acid (LCA), a metabolite induced by calorie restriction (CR), activates AMPK and mimics anti-aging benefits. A recent study highlights LCA's role in improving muscle performance, glucose tolerance, and lifespan in aged organisms.

1 Jan 2025

Taxi and ambulance drivers show lower Alzheimer’s risk

Study reveals that taxi and ambulance drivers, whose jobs demand frequent spatial and navigational processing, have lower Alzheimer's disease-related mortality compared to other professions. These findings suggest a potential link between occupational cognitive demands and AD risk.

1 Jan 2025