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2013 World Stem Cell Report to be published as special supplement to journal Stem Cells and Development

The Genetics Policy Institute and Mary Ann Liebert, Inc., publishers have announced that the 2013 World Stem Cell Report will be published as a special supplement to the peer-reviewed journal Stem Cells and Development. Dr. Graham Parker and Bernard Siegel will serve as Co-Editors-in-Chief, joined by Rosario Isasi (McGill University) as Managing Editor.

11 Jun 2013

Data points to potential role of immunosuppression in protecting organs from inflammation after injury

In the largest study of its kind, physicians from the Department of Surgery at the University of Maryland School of Medicine and the R Adams Cowley Shock Trauma Center at the University of Maryland Medical Center have determined that outcomes for traumatic injury in patients with organ transplants are not worse than for non-transplanted patients, despite common presumptions among physicians.

11 Jun 2013

Cytosine methylation plays key role in development of childhood ALL

Changes in an epigenetic mechanism that turns expression of genes on and off may be as important as genetic alterations in causing pediatric acute lymphoblastic leukemia, according to a study led by scientists at St. Jude Children's Research Hospital and published in the June 10 online edition of the Journal of Clinical Investigation.

11 Jun 2013

Researchers receive grant from Arthritis Research UK to study genes associated with hip osteoarthritis

Medical research charity Arthritis Research UK has awarded £250,000 to a team of researchers at the University of Bristol and the University of Aberdeen to study which genes can lead to people developing painful and common osteoarthritis of the hip.

11 Jun 2013

Researchers find master regulator of EMT and metastasis

The predominant cause of death in cancer patients is metastasis, the formation of secondary tumors in other organs like the brain, liver, and lungs. Cancer cells detach from the original primary tumor and reach a single cell or group of cells in another organ. The cells of the body normally remain in place through adhering to an extracellular substance. However, cancer cells learn how to release themselves from these bonds and invade surrounding tissues, blood, and the lymphatic system.

11 Jun 2013

Researchers move closer to specific therapy to treat triple receptor-negative breast cancer

The search for a specific therapy to treat a particularly aggressive type of breast cancer has moved a step forward thanks to new research carried out by the University of Essex.

10 Jun 2013

African medicinal plants contain chemicals that may help stop spread of cancer cells

African medicinal plants contain chemicals that may be able to stop the spread of cancer cells. This is the conclusion of researchers following laboratory experiments conducted at Johannes Gutenberg University Mainz (JGU).

10 Jun 2013

New technique for identifying mice in breeding colonies

Immunocompromised mice, created by inactivating the genes that would allow them to recognize and attack donor cells or organs, are critical for studies of bone marrow reconstitution.

10 Jun 2013

Bone tumor identified in the rib of 120,000-year-old Neandertal

The first-known definitive case of a benign bone tumor has been discovered in the rib of a young Neandertal who lived about 120,000 years ago in what is now present-day Croatia.

10 Jun 2013

Scientists find that mice develop age-related progressive motor symptoms of Parkinson's disease

The presence of Lewy bodies in nerve cells, formed by intracellular deposits of the protein α-synuclein, is a characteristic pathologic feature of Parkinson's Disease (PD). In the quest for an animal model of PD that mimics motor and non-motor symptoms of human PD, scientists have developed strains of mice that overexpress α-synuclein.

10 Jun 2013

Drug used to control Type II diabetes can help repair spinal cords of mice suffering from inherited disease

A drug used to control Type II diabetes can help repair the spinal cords of mice suffering from the inherited disease adrenoleukodystrophy which, untreated, leads eventually to a paralysis, a vegetative state and death.

10 Jun 2013

Blood vessels within sensory area of mammalian brain loop connect in unexpected ways, new map reveals

Blood vessels within a sensory area of the mammalian brain loop and connect in unexpected ways, a new map has revealed.

10 Jun 2013

New non-invasive test measures methylation of SDC2 gene, detects 87% of colorectal cancer

The average 5-year survival for colorectal cancer (CRC) is less than 10% if metastasis occurs, but can reach 90% if detected early. A new non-invasive test has been developed that measures methylation of the SDC2 gene in tissues and blood sera.

10 Jun 2013

Common antidepressant medications may impair a form of learning, new report suggests

An interesting new report of animal research published in Biological Psychiatry suggests that common antidepressant medications may impair a form of learning that is important clinically.

10 Jun 2013

Whitehead Institute researchers identify drug target for anemia

Researchers at Whitehead Institute have identified a protein that is the target of glucocorticoids, the drugs that are used to increase red blood cell production in patients with certain types of anemia, including those resulting from trauma, sepsis, malaria, kidney dialysis, and chemotherapy.

10 Jun 2013

Viewpoints: Will 'rate shock' grow?; Krugman says GOP spite is driving opposition to Medicaid expansion; Determining who owns genes

Any plausible health care reform, the various conservative alternatives to Obamacare included, would necessarily have losers as well as winners, and as far as potential losers go single young men with above-average incomes are not precisely the country's most disadvantaged demographic. If you think the current system is flawless, then I suppose any rate increase anywhere is a strike against health care reform.

10 Jun 2013

Novel abnormalities in FGFR gene identified in a spectrum of cancers

Novel abnormalities in the FGFR gene, called FGFR fusions, were identified in a spectrum of cancers, and preliminary results with cancer cells harboring FGFR fusions suggested that some patients with these cancers may benefit from treatment with FGFR inhibitor drugs, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.

10 Jun 2013

Second-annual SINAInnovations conference to highlight power of Team Science

Leaders in health care, technology, design, the military and the arts will gather at The Mount Sinai Medical Center for the second-annual SINAInnovations conference on November 18 and 19, 2013.

10 Jun 2013

Optogenetics: A promising technique for treatment of obsessive-compulsive disorders

By applying light stimulation to highly specific neurons in the brain, the researchers managed to re-establish normal behaviour in mice that had beforehand presented pathological repetitive behaviour similar to that observed in human patients suffering from obsessive-compulsive disorders.

10 Jun 2013

Genetic testing for cancer-causing mutations in affected families is very low, study finds

A new study of the use of genetic testing for cancer-causing mutations in affected families in France has found that its take-up is very low.

10 Jun 2013

Medical Science News

2013 World Stem Cell Report to be published as special supplement to journal Stem Cells and Development

Data points to potential role of immunosuppression in protecting organs from inflammation after injury

Cytosine methylation plays key role in development of childhood ALL

Researchers receive grant from Arthritis Research UK to study genes associated with hip osteoarthritis

Researchers find master regulator of EMT and metastasis

Researchers move closer to specific therapy to treat triple receptor-negative breast cancer

African medicinal plants contain chemicals that may help stop spread of cancer cells

New technique for identifying mice in breeding colonies

Bone tumor identified in the rib of 120,000-year-old Neandertal

Scientists find that mice develop age-related progressive motor symptoms of Parkinson's disease

Drug used to control Type II diabetes can help repair spinal cords of mice suffering from inherited disease

Blood vessels within sensory area of mammalian brain loop connect in unexpected ways, new map reveals

New non-invasive test measures methylation of SDC2 gene, detects 87% of colorectal cancer

Common antidepressant medications may impair a form of learning, new report suggests

Whitehead Institute researchers identify drug target for anemia

Viewpoints: Will 'rate shock' grow?; Krugman says GOP spite is driving opposition to Medicaid expansion; Determining who owns genes

Novel abnormalities in FGFR gene identified in a spectrum of cancers

Second-annual SINAInnovations conference to highlight power of Team Science

Optogenetics: A promising technique for treatment of obsessive-compulsive disorders

Genetic testing for cancer-causing mutations in affected families is very low, study finds

Building Bridges to Scalable Allogeneic Cell Therapy

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

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