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Data emphasise need for comprehensive analysis of mtDNA in mitochondrial disease patients

French scientists have discovered that supposedly rare mutations in the mitochondria, the 'power plants' of human cells responsible for creating energy, account for more than 7% of patients with a mitochondrial disease manifesting itself as a respiratory deficiency.

10 Jun 2013

Scientists discover how Arc protein helps translate learning into memory

Scientists at the Gladstone Institutes have deciphered how a protein called Arc regulates the activity of neurons-providing much-needed clues into the brain's ability to form long-lasting memories. These findings, reported today in Nature Neuroscience, also offer newfound understanding as to what goes on at the molecular level when this process becomes disrupted.

10 Jun 2013

Essential fatty acid found in vegetable oils does not promote inflammation in humans, scientists find

A typical American consumes approximately 3 or more tablespoons of vegetable oil each day. Vegetable oils, like those from soy, corn and canola, are a significant source of calories and are rich in linoleic acid, which is an essential nutrient.

10 Jun 2013

McGill researchers use computer simulations to show how immune cells identify foreign antigens

How do immune cells manage to sort through vast numbers of similar-looking proteins within the body to detect foreign invaders and fight infections?

10 Jun 2013

USC scientists unlock mystery of why new cases of Noonan Syndrome are so common

Scientists at USC have unlocked the mystery of why new cases of the genetic disease Noonan Syndrome are so common: a mutation that causes the disease disproportionately increases a normal father's production of sperm carrying the disease trait.

10 Jun 2013

Researchers discover potential target for cancer-fighting drugs

As tumors grow, their centers are squeezed of oxygen. And so tumors must flip specific genetic switches to survive in these hypoxic environments.

10 Jun 2013

Study sheds light on origin of wide range of brain disorders

Researchers at Weill Cornell Medical College have uncovered a mechanism that guides the exquisite wiring of neural circuits in a developing brain -- gaining unprecedented insight into the faulty circuits that may lead to brain disorders ranging from autism to mental retardation.

10 Jun 2013

Researchers find new way to repair genetic defects in the skin cells of epidermolysis bullosa patients

A research team led by pediatric blood and marrow transplantation experts Mark Osborn, Ph.D. and Jakub Tolar, M.D., Ph.D. from the Masonic Cancer Center, University of Minnesota, have discovered a remarkable new way to repair genetic defects in the skin cells of patients with the skin disease epidermolysis bullosa.

10 Jun 2013

Researchers find way to differentiate iPSCs into mature human neurons in the brain

Difficult-to-study diseases such as Alzheimer's, schizophrenia, and autism now can be probed more safely and effectively thanks to an innovative new method for obtaining mature brain cells called neurons from reprogrammed skin cells. According to Gong Chen, the Verne M. Willaman Chair in Life Sciences and professor of biology at Penn State University and the leader of the research team, "the most exciting part of this research is that it offers the promise of direct disease modeling, allowing for the creation, in a Petri dish, of mature human neurons that behave a lot like neurons that grow naturally in the human brain."

10 Jun 2013

Liver regeneration using cell therapy may be possible, study suggests

Liver transplantation is the mainstay of treatment for patients with end-stage liver disease, the 12th leading cause of death in the United States, but new research from the Icahn School of Medicine at Mount Sinai, published in the online journal Cell Stem Cell today, suggests that it may one day become possible to regenerate a liver using cell therapy in patients with liver disease.

10 Jun 2013

New method allows omega-3 fatty acids to be added to popular foods

The omega-3 fatty acids contained in fatty salt-water fish are an important component of a healthy diet in humans. Despite being aware of this fact, Germans still do not eat enough fish. Now Fraunhofer researchers have developed a method that allows omega-3 fatty acids to be added to popular foods.

7 Jun 2013

Researchers mobilize brain's native stem cells to replenish neuron lost in Huntington's disease

Researchers have been able to mobilize the brain's native stem cells to replenish a type of neuron lost in Huntington's disease.

7 Jun 2013

Cancer cells' appetite for sugar may have serious consequences for immune cell function

Cancer cells' appetite for sugar may have serious consequences for immune cell function, researchers at Washington University School of Medicine in St. Louis have learned.

7 Jun 2013

Rewinding the developmental state of embryonic stem cells is possible, say researchers

Scientists at the Danish Stem Cell Center, DanStem, at the University of Copenhagen have discovered that they can make embryonic stem cells regress to a stage of development where they are able to make placenta cells as well as the other fetal cells.

7 Jun 2013

Genetic testing of chronic neutrophilic leukemia reveals presence of new mutation in patients

A recent article in the New England Journal of Medicine describes genetic testing of a rare blood cancer called atypical chronic neutrophilic leukemia (CNL) that revealed a new mutation present in most patients with the disease.

7 Jun 2013

Human Argonautes directly cuts messenger RNA

Human Argonautes (hAgo), are key proteins involved in a process known as RNA interference. RNAi, as it is often called, is a mechanism that cells use to regulate gene expression.

7 Jun 2013

Researcher studies mechanism of s-looping to prevent heart abnormalities in infants

Ashok Ramasubramanian, assistant professor of mechanical engineering at Union College, believes that the study of the tiny tubes that make up the embryonic heart offers new hope to babies born with heart abnormalities. So, he's looking to chicken embryos for clues. Ramasubramanian's findings were published in the April 2013 issue of Developmental Dynamics.

7 Jun 2013

White Paper provides recommendations to create ecosystem for use of Nanomedicine in Europe

The European Technology Platform on Nanomedicine and the NANOMED2020 project announce the publication of the White Paper on Contribution of Nanomedicine to Horizon 2020, the next European Framework Programme for Research and Innovation till 2020.

7 Jun 2013

Cow antibodies points to new ways for making human medicines

Humans have been raising cows for their meat, hides and milk for millennia. Now it appears that the cow immune system also has something to offer. A new study led by scientists from The Scripps Research Institute (TSRI) focusing on an extraordinary family of cow antibodies points to new ways to make human medicines.

7 Jun 2013

Researchers demonstrate how young genes acquire essential functions

Researchers from UConn and other institutions in the U.S. and abroad have shown how a relatively young gene can acquire a new function and become essential to an organism's life.

7 Jun 2013

Medical Science News

Data emphasise need for comprehensive analysis of mtDNA in mitochondrial disease patients

Scientists discover how Arc protein helps translate learning into memory

Essential fatty acid found in vegetable oils does not promote inflammation in humans, scientists find

McGill researchers use computer simulations to show how immune cells identify foreign antigens

USC scientists unlock mystery of why new cases of Noonan Syndrome are so common

Researchers discover potential target for cancer-fighting drugs

Study sheds light on origin of wide range of brain disorders

Researchers find new way to repair genetic defects in the skin cells of epidermolysis bullosa patients

Researchers find way to differentiate iPSCs into mature human neurons in the brain

Liver regeneration using cell therapy may be possible, study suggests

New method allows omega-3 fatty acids to be added to popular foods

Researchers mobilize brain's native stem cells to replenish neuron lost in Huntington's disease

Cancer cells' appetite for sugar may have serious consequences for immune cell function

Rewinding the developmental state of embryonic stem cells is possible, say researchers

Genetic testing of chronic neutrophilic leukemia reveals presence of new mutation in patients

Human Argonautes directly cuts messenger RNA

Researcher studies mechanism of s-looping to prevent heart abnormalities in infants

White Paper provides recommendations to create ecosystem for use of Nanomedicine in Europe

Cow antibodies points to new ways for making human medicines

Researchers demonstrate how young genes acquire essential functions

Building Bridges to Scalable Allogeneic Cell Therapy

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

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