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Breakthrough in artificial sugars could revolutionize disease diagnosis and treatment

Scientists have found a way to create artificial sugars that could lead to better ways to diagnose and treat diseases more accurately than ever before.

16 Sep 2024

Climate change shaped human evolution, driving migration and cultural adaptation across ancient landscapes

Researchers reveal how past climate shifts and vegetation changes drove the evolution and migration of early human species during the Pleistocene.

15 Sep 2024

Key enzyme identified as potential target for cancer treatment

During every moment of any living organism's life, enzymes are at work. These crucial proteins support life through most biological processes, including metabolism, movement, respiration, and digestion.

14 Sep 2024

Innovative heart valve technology could improve patient lives

Now, a team of UBC Okanagan researchers believe they have found a way to harness the strengths of both technologies in a way that could be life-changing - and life-saving - for many. Dr. Hadi Mohammadi and his fellow researchers in the Heart Valve Performance Laboratory at UBC Okanagan are focused on developing the mechanical heart valves of the future.

14 Sep 2024

Study identifies common misuses of spike-in normalization

Researchers at University of California San Diego have published new guidelines that could help scientists significantly improve their results when quantifying the interactions between DNA and proteins. Understanding these interactions is critical to our understanding of human biology in general, and can also help scientists develop new treatments for a wide range of diseases, including many cancers.

14 Sep 2024

Scientists develop novel technique to combat T cell exhaustion

Fighting cancer is exhausting for T cells. Hostile tumor microenvironments can drain their mitochondrial activity, leading to a condition known as T cell exhaustion. This phenomenon also hinders adoptive cell therapies, in which healthy, tumor-targeting T cells are infused into patients with cancer. A novel method to boost mitochondrial activity and charge up T cells is needed.

14 Sep 2024

Mount Sinai researchers uncover genetic basis of fibromuscular dysplasia

Mount Sinai researchers have identified a key driver of a blood vessel disorder known as fibromuscular dysplasia (FMD) which affects up to five percent of the adult population and can lead to high blood pressure, heart attack, or stroke.

14 Sep 2024

New insight into the causes of autoimmune diseases

Autoimmune diseases are widespread and notoriously difficult to treat. In part, this is because why the immune system attacks its own tissues in patients with these conditions remains poorly understood.

14 Sep 2024

Real-world data reveals factors associated with long-term weight loss in obesity

A Cleveland Clinic study identified key factors that can impact the long-term weight loss of patients with obesity who were prescribed injectable semaglutide or liraglutide for the treatment of type 2 diabetes or obesity. The study was published in JAMA Network Open.

14 Sep 2024

Evolution of vaccine adjuvants from empirical discovery to rational design

Vaccine adjuvants have evolved significantly since their inception, transitioning from empirical discovery to a more structured approach grounded in rational drug design.

13 Sep 2024

Study reveals how SARS-CoV-2 triggers diabetes by destroying pancreatic cells

Researchers from Weill Cornell Medicine have used a cutting-edge model system to uncover the mechanism by which SARS-CoV-2, the virus that causes COVID-19, induces new cases of diabetes, and worsens complications in people who already have it.

13 Sep 2024

Low manganese levels found to worsen inflammatory bowel conditions

Researchers at the University of Michigan have delved deeper into the relationship between manganese deficiency and inflammatory bowel disease and found that low levels of the micronutrient can exacerbate intestinal injury and inflammation.

13 Sep 2024

PPARs and PROTACs: A new strategy in cancer therapeutics

The growing challenge in cancer therapy lies in overcoming tumor heterogeneity, drug resistance, and associated side effects.

13 Sep 2024

New biomarker helps differentiate Alzheimer’s from primary 4-repeat tauopathies

A new biomarker makes it easier to distinguish between Alzheimer's and primary tauopathy.

13 Sep 2024

Breakthrough in understanding formaldehyde toxicity during development and aging

AMeD syndrome is a severe genetic condition found in children that present with accelerated aging, global developmental delay and bone marrow failure, among others, progressing to Myelodysplastic Syndrome and Acute Myeloid Leukaemia.

13 Sep 2024

Breakthrough study sheds light on mechanisms behind the spread of gastric cancer to the peritoneum

Gastric cancer remains a formidable adversary, ranking as the fifth most common cancer and the third-leading cause of cancer-related deaths worldwide, with over 1,000,000 new cases and close to 770,000 deaths each year.

13 Sep 2024

New blood test achieves 98% accuracy in diagnosing ALS

A highly accurate diagnostic blood test has been developed for amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease that effects neurons in the brain and spinal cord.

13 Sep 2024

ISM2196: A promising AI-developed WRN inhibitor for advanced metastatic cancers

Insilico Medicine("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced the nomination of ISM2196, an AI-driven, potential best-in-class small molecule WRN inhibitor targeting advanced metastatic microsatellite instability (MSI) cancers guided by synthetic lethality strategy.

13 Sep 2024

Advances in targeting the CD47/SIRPα "do not eat me" pathway for cancer therapy

A new editorial was recently published in Oncotarget's Volume 15, on July 10, 2024, entitled, "The advances in targeting CD47/SIRPα "do not eat me" axis and their ongoing challenges as an anticancer therapy."

13 Sep 2024

Study finds brain synchronization between humans and dogs during social interactions

During social interactions, the activity of the brain's neurons becomes synchronized between the individuals involved.

13 Sep 2024

Medical Science News

Breakthrough in artificial sugars could revolutionize disease diagnosis and treatment

Climate change shaped human evolution, driving migration and cultural adaptation across ancient landscapes

Key enzyme identified as potential target for cancer treatment

Innovative heart valve technology could improve patient lives

Study identifies common misuses of spike-in normalization

Scientists develop novel technique to combat T cell exhaustion

Mount Sinai researchers uncover genetic basis of fibromuscular dysplasia

New insight into the causes of autoimmune diseases

Real-world data reveals factors associated with long-term weight loss in obesity

Evolution of vaccine adjuvants from empirical discovery to rational design

Study reveals how SARS-CoV-2 triggers diabetes by destroying pancreatic cells

Low manganese levels found to worsen inflammatory bowel conditions

PPARs and PROTACs: A new strategy in cancer therapeutics

New biomarker helps differentiate Alzheimer’s from primary 4-repeat tauopathies

Breakthrough in understanding formaldehyde toxicity during development and aging

Breakthrough study sheds light on mechanisms behind the spread of gastric cancer to the peritoneum

New blood test achieves 98% accuracy in diagnosing ALS

ISM2196: A promising AI-developed WRN inhibitor for advanced metastatic cancers

Advances in targeting the CD47/SIRPα "do not eat me" pathway for cancer therapy

Study finds brain synchronization between humans and dogs during social interactions

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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