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Human challenge trials: A game-changer in vaccine development? Examining their role in shaping the pandemic response

The history of using human challenge trials in developing vaccines.

15 Aug 2023

Genetic determinants of retinol circulation and their impact on health

The genetic architecture of circulating retinol.

15 Aug 2023

The mutual health benefits resulting from the relationship between owners and their dogs

The mutual health benefits for dogs and their owners.

15 Aug 2023

Can nutritional interventions positively impact psoriasis severity?

Improvement in psoriasis (Ps) through nutritional strategies.

15 Aug 2023

Can fasting benefit individuals with diabetes?

Fasting and its effect on diabetes.

15 Aug 2023

Is COVID-19 self-testing effective?

Real-world evidence on the performance of coronavirus disease 2019 (COVID-19) self-testing strategies.

15 Aug 2023

Investigating the potential differences in waning of post-vaccination neutralizing antibody titers

The decline patterns of neutralizing antibodies following coronavirus disease 2019 (COVID-19) vaccination.

15 Aug 2023

A computational model identifies metabolites associated with Parkinson's disease

Researchers identify significant metabolites involved in the development and progression of Parkinson’s disease.

15 Aug 2023

Epigenetic drug-sensitive biomarkers for cancer

Researchers perform an epigenome-wide multi-omic high-throughput screen to identify actionable epigenetic drug-sensitive biomarkers.

15 Aug 2023

Peripheral tumor biomarkers to guide treatment for HPV-associated malignancies

A new review paper was published in Oncotarget's Volume 14 on August 10, 2023, entitled, "Peripheral surrogates of tumor burden to guide chemotherapeutic and immunotherapeutic strategies for HPV-associated malignancies."

14 Aug 2023

Oncolytic viruses could be used to 'warm up' cold tumors and improve immunotherapy

Equipping cancer-infecting, or oncolytic, viruses with tumor-inhibiting genetic cargo stimulates the immune system and helps immunotherapy to shrink or completely clear aggressive tumors in mice, according to a new study in the Journal of Experimental Medicine led by University of Pittsburgh and UPMC researchers.

14 Aug 2023

Study finds way to reverse gene silencing in inner ear cells

A deafened adult cannot recover the ability to hear, because the sensory hearing cells of the inner ear don't regenerate after damage.

14 Aug 2023

Stem cells used to create organoids that secrete dental enamel proteins

Organoids have now been created from stem cells to secrete the proteins that form dental enamel, the substance that protects teeth from damage and decay.

14 Aug 2023

Study discovers new mechanism for deadly tumor switch in prostate cancer

A study from the University of Michigan Rogel Cancer Center uncovers a new mechanism to explain why some prostate tumors switch from a common, treatable form to a more rare and aggressive form of prostate cancer.

14 Aug 2023

Scientists identify key proteins driving cancer across multiple tumor types

Scientists have completed a deep analysis of the proteins driving cancer across multiple tumor types, information that can't be assessed by genome sequencing alone.

14 Aug 2023

Study yields new knowledge about genes responsible for IgG production and release

A collaboration led by UCLA and the Seattle Children's Research Institute has yielded new knowledge about the genes responsible for the production and release of immunoglobulin G, the most common type of antibody in the human body.

14 Aug 2023

UAB researchers identify cell-surface marker that indicates fate of T cells

Follicular helper T cells, or Tfh cells, have a crucial role in immune defense. Without Tfh cells, B cells cannot form germinal center, or GC, responses during which high-affinity antibodies are generated.

14 Aug 2023

Digital puzzle games can improve memory in older adults

Older adults who play digital puzzle games have the same memory abilities as people in their 20s, a new study has shown.

14 Aug 2023

Columbia researchers shed light on puzzling phenomenon in brain-injured patients

Columbia researchers have identified brain injuries that may underlie hidden consciousness, a puzzling phenomenon in which brain-injured patients are unable to respond to simple commands, making them appear unconscious despite having some level of awareness.

14 Aug 2023

Scientists uncover new molecular targets for cardiovascular regulation

Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States and a leading research center for diabetes and other life-threatening illnesses, have uncovered new molecular targets on a cell receptor that play a major role in cardiovascular regulation.

14 Aug 2023