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Small biotech companies join with pharmaceutical giants to manufacture drugs

Many of the most promising new molecules to treat diseases come from smaller biotechnology firms, which often lack resources to scale up production when it's time for their drugs to go to large-scale clinical trials or the market.

30 Jun 2021

Antibody development against SARS-CoV-2 following Moderna vaccine

In a paper recently uploaded to the preprint server medRxiv* by Belda et al. (June 27th, 2021) two seroconversion panels containing the sera of individuals that received the Moderna (mRNA-1273) vaccine are compared, and the impact on neutralizing IgG antibody titers in these individuals is analyzed.

30 Jun 2021

FDA approves alternative component of chemotherapy regimen to treat acute lymphoblastic leukemia

Today, the U.S. Food and Drug Administration approved Rylaze (asparaginase erwinia chrysanthemi (recombinant)-rywn) as a component of a chemotherapy regimen to treat acute lymphoblastic leukemia and lymphoblastic lymphoma in adult and pediatric patients who are allergic to the E. coli-derived asparaginase products used most commonly for treatment.

30 Jun 2021

SARS-CoV-2 inhibited by pyrimidine biosynthesis inhibitors in conjunction with nucleoside analogs

In an effort to hasten the research on identifying antiviral drugs for SARS-CoV-2 infection, researchers from the U.S. and Switzerland performed extensive drug screening for antiviral activity using live virus infection in human respiratory cells. As a result, they identified a set of possible drug candidates that could potentially be tested in clinical trials.

30 Jun 2021

New neuronal circuit may help control which sensory information is relayed to the auditory cortex

A team of neuroscientists at the Beckman Institute for Advanced Science and Technology led by Baher Ibrahim and Dr. Daniel Llano published a study in eLife that furthers our understanding of how the brain perceives everyday sensory inputs.

30 Jun 2021

NIH-funded adjuvant improves the efficacy India's COVID-19 vaccine

An adjuvant developed with funding from the National Institutes of Health has contributed to the success of the highly efficacious COVAXIN COVID-19 vaccine, which roughly 25 million people have received to date in India and elsewhere.

30 Jun 2021

Many survivors of adolescent and young adult cancers hesitate to get COVID-19 vaccinations

A new paper in JNCI Cancer Spectrum, published by Oxford University Press, indicates that many survivors of adolescent and young adult cancers hesitate to obtain COVID-19 vaccinations.

29 Jun 2021

Public opinion surveys could be used to understand regional variation in vaccine hesitancy, say experts

Public opinion surveys could be used more widely to understand regional variation in vaccine hesitancy, experts have recommended.

29 Jun 2021

FDA's controversial decision to approve aducanumab for Alzheimer's treatment raises major ethical issues

The U.S. Food and Drug Administration's controversial decision to approve aducanumab for the treatment of Alzheimer's disease raises at least three major ethical issues that need to be addressed, states a new article in the Hastings Center Report:

29 Jun 2021

Cyber security experts may hold the key to rollout of vaccine passports

Leading cybersecurity industry expert, Koji Fusa, has made progress towards developing a framework for the world's citizens to store their digital identities and access them in real-time. Koji is a Visiting Professor at the Cyber Security Innovation Research Centre (CSI) at Aston University.

29 Jun 2021

Immune response to FDA-approved vaccines is strong and potentially long-lasting

The first two COVID-19 vaccines authorized for emergency use by the Food and Drug Administration (FDA) employed a technology that had never before been used in FDA-approved vaccines.

29 Jun 2021

New drug candidate may reduce anxiety-like behavior in mice

Anxiety, commonly termed as a feeling of fear, dread, and restlessness, is a perfectly normal reaction to stressful situations. However, a state of heightened anxiety, which is the reality for thousands of people who struggle to cope with these feelings, is called anxiety disorder.

29 Jun 2021

Anti-cancer prodrug can benefit cancer patients

Unlike conventional cancer drugs that attack and kill cancer cells directly, anti-cancer immunotherapy, which kills cancer cells by strengthening the body's immunity, is a novel type of cancer treatment currently attracting increased attention. Unfortunately, a minority of cancer patients who have some degree of pre-existing immunity only benefit from anti-cancer immunotherapy.

28 Jun 2021

An oral pill for COVID-19? Molnupiravir shows promise

Recently, researchers reported molnupiravir as the first oral and direct-acting antiviral that is highly effective at reducing SARS-CoV-2 levels.

27 Jun 2021

Performance-enhancing substance use is longitudinally associated with criminal offending

Despite research showing associations between anabolic steroid use and criminal offending, the possibility of a similar association between legal performance-enhancing substance use, such as creatine, and criminal offending remained unknown.

25 Jun 2021

Comprehensive reference on the science, technology, and applications of postbiotics

Postbiotics: Science, Technology, and Applications explains essential and practical knowledge about postbiotics. Chapters cover the definition and classification of postbiotics, principal methods for preparing them, information about the main post biotic constituents and their biological activities and their clinical health benefits.

25 Jun 2021

Over-the-counter antacids may improve glucose levels in people with diabetes

Antacids improved blood sugar control in people with diabetes but had no effect on reducing the risk of diabetes in the general population, according to a new meta-analysis published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

25 Jun 2021

Remdesivir caused dangerously low heart rate in COVID-19 patients

After beginning treatment with remdesivir for COVID-19, a patient experienced significant bradycardia, or low heart rate. Her physicians used a dopamine infusion to stabilize her through the five-day course of remdesivir treatment, and her cardiac condition resolved itself at the end of the treatment.

25 Jun 2021

Many people with fibromyalgia substitute CBD for opioids and pain medications, finds study

Fibromyalgia is one of many chronic pain conditions that remains stubbornly difficult to treat.

24 Jun 2021

Antidepressants taken during pregnancy do not increase risk for autism spectrum disorder

Women with depression and other mood disorders are generally advised to continue taking antidepressant medications during pregnancy.

24 Jun 2021

Pharmaceutical News

Small biotech companies join with pharmaceutical giants to manufacture drugs

Antibody development against SARS-CoV-2 following Moderna vaccine

FDA approves alternative component of chemotherapy regimen to treat acute lymphoblastic leukemia

SARS-CoV-2 inhibited by pyrimidine biosynthesis inhibitors in conjunction with nucleoside analogs

New neuronal circuit may help control which sensory information is relayed to the auditory cortex

NIH-funded adjuvant improves the efficacy India's COVID-19 vaccine

Many survivors of adolescent and young adult cancers hesitate to get COVID-19 vaccinations

Public opinion surveys could be used to understand regional variation in vaccine hesitancy, say experts

FDA's controversial decision to approve aducanumab for Alzheimer's treatment raises major ethical issues

Cyber security experts may hold the key to rollout of vaccine passports

Immune response to FDA-approved vaccines is strong and potentially long-lasting

New drug candidate may reduce anxiety-like behavior in mice

Anti-cancer prodrug can benefit cancer patients

An oral pill for COVID-19? Molnupiravir shows promise

Performance-enhancing substance use is longitudinally associated with criminal offending

Comprehensive reference on the science, technology, and applications of postbiotics

Over-the-counter antacids may improve glucose levels in people with diabetes

Remdesivir caused dangerously low heart rate in COVID-19 patients

Many people with fibromyalgia substitute CBD for opioids and pain medications, finds study

Antidepressants taken during pregnancy do not increase risk for autism spectrum disorder

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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