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Durable antibody response at least 8 months following vaccination with J&J COVID vaccine

A recent study by a team of scientists at Beth Israel Deaconess Medical Center and Janssen Vaccines & Prevention has demonstrated that humoral and cellular immunity elicited by the coronavirus disease 2019 (COVID-19) vaccine Ad26.COV2.S remains active for at least eight months.

9 Jul 2021

LGM Pharma launches standalone analytical services for drug developers and manufacturers

LGM Pharma today announced the launch of its new Analytical Services offering that provides analytical testing and stability services to pharmaceutical developers and manufacturers, including compounding pharmacies.

From LGM Pharma 8 Jul 2021

New analysis finds muscle relaxant drugs to be largely ineffective for low back pain

Muscle relaxant drugs are largely ineffective for low back pain, despite being widely prescribed for this condition, suggests an analysis of the latest evidence published by The BMJ today.

8 Jul 2021

Striking increase in SARS-CoV-2 antibodies seen with prime dose AstraZeneca vaccine followed by Pfizer-BioNTech

Researchers in Germany have provided evidence that a booster shot of a messenger RNA (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine following prime immunization with AstraZeneca’s adenoviral vector-based vaccine is sufficient to achieve high levels of neutralizing antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

8 Jul 2021

Study: Opioid prescribing preferences, practices among surgical residents and faculty differ

Opioid prescribing preferences and practices among surgical residents and faculty differ, according to a new study published in the journal Surgery.

8 Jul 2021

Interleukin-6 antagonists benefit hospitalized patients with COVID-19

Findings from a study published today [6 July] in the Journal of the American Medical Association (JAMA) have prompted new World Health Organization (WHO) recommendations to use interleukin-6 antagonists in patients with severe or critical COVID-19 along with corticosteroids.

7 Jul 2021

Doctors advise against off-label use of new Alzheimer's medicine for cerebral amyloid angiopathy

A novel therapy recently approved by the U.S. Food and Drug Administration for patients with Alzheimer's disease amid considerable controversy should not be prescribed by physicians off-label for cerebral amyloid angiopathy (CAA), a similar cerebrovascular condition, according to Steven Greenberg, MD, PhD, director of the Hemorrhagic Stroke Research Program at Massachusetts General Hospital (MGH) and president of the International Cerebral Amyloid Angiopathy Association (ICAAA).

7 Jul 2021

Plant compounds inhibit Mpro of SARS-CoV-2 and HCoV-229E in vitro

A group of researchers recently discussed their findings that a group of plant flavonols and dihydroflavonols exhibit antiviral efficacy against both SARS-CoV-2 and HCoV-229E.

6 Jul 2021

Investigation reveals considerable added benefit of remdesivir for moderately ill COVID-19 patients

Since July 2020, remdesivir has been conditionally approved in Europe for the treatment of coronavirus disease (COVID-19) in adults and adolescents aged 12 years and older with pneumonia who require supplemental oxygen but no invasive ventilation.

6 Jul 2021

Anti-rheumatic drug combinations could reduce the risk of heart attack and strokes

New research evaluating the drugs commonly used by rheumatoid arthritis patients suggests two combinations could reduce the risk of heart attack and strokes.

6 Jul 2021

Antibiotic clofoctol shows potential against SARS-CoV-2

In a recent study, a group of French researchers aimed to reduce the regulatory preclinical development steps that potential candidates are normally subjected to.

5 Jul 2021

Novavax COVID-19 vaccine demonstrates ~90% efficacy against SARS-CoV-2

The findings reveal that the two-dose regimen of the vaccine is almost 90% effective against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Moreover, the vaccine shows high efficacy against the B.1.1.7 variant (Alpha) of SARS-CoV-2.

5 Jul 2021

Study evaluates the difference in weight loss caused by two antidiabetic medications

Patients with Type 2 diabetes who were prescribed SGLT2 inhibitors lost more weight than patients who received GLP-1 receptor agonists, according to a University at Buffalo-led study.

2 Jul 2021

Study evaluates neutralizing antibody responses elicited by the Pfizer/BioNTech COVID-19 vaccine

A recent Diagnostics study discusses the specific antibody response that occurred in individuals after they had received the SARS-CoV-2 vaccine.

1 Jul 2021

Can age, sex, BMI or blood group influence the immunogenicity of the Pfizer/BioNTech COVID-19 vaccine?

A group of Belgium researchers recently discuss their findings in the journal Microorganisms, which describe the influence of several factors on vaccine-induced immunogenicity.

1 Jul 2021

COVID-19 vaccines are effective in 94% of cancer patients, shows study

In a U.S. and Swiss study, nearly all patients with cancer developed good immune response to the COVID-19 mRNA vaccines three to four weeks after receiving their second dose, but the fact that a small group of the patients exhibited no response raised questions about how their protection against the virus will be addressed moving forward.

1 Jul 2021

Objective Structured Clinical Examinations can help assess clinical skills of future pharmacists

A recent University of Arizona College of Pharmacy study suggests that Objective Structured Clinical Examinations (OSCEs) may be a valuable means of assessing clinical skills while providing learning experiences for pharmacy students in community pharmacy settings.

1 Jul 2021

Individuals who contract COVID-19 after vaccination are likely to have a lower viral load

Individuals who contract COVID-19 even after vaccination are likely to have a lower viral load, experience a shorter infection time and have milder symptoms than people who are unvaccinated, according to research that includes data from ongoing University of Arizona Health Sciences studies.

1 Jul 2021

New article focuses on drug discovery targeting SARS-CoV-2

The July edition of SLAS Discovery is a Special Edition featuring the cover article, "Development of a High-Throughput Screening Assay to Identify Inhibitors of the SARS-CoV-2 Guanine-N7-Methyltransferase Using RapidFire Mass Spectrometry" by Lesley-Anne Pearson, Charlotte J. Green, Ph.D., De Lin, Ph.D., Alain-Pierre Petit, Ph.D., David W. Gray, Ph.D., Victoria H. Cowling, Ph.D., and Euan A. F. Fordyce, Ph.D., (Drug Discovery Unit, School of Life Sciences, University of Dundee, Dundee, UK).

1 Jul 2021

Ion channel conserved in coronaviruses a potential new drug target for COVID therapeutics

To this end, a recent study published in Nature Structural & Molecular Biology discusses the structures of the SARS-CoV-2 ORF3a using cryo-electron microscopy (cryo-EM).

30 Jun 2021

Pharmaceutical News

Durable antibody response at least 8 months following vaccination with J&J COVID vaccine

LGM Pharma launches standalone analytical services for drug developers and manufacturers

New analysis finds muscle relaxant drugs to be largely ineffective for low back pain

Striking increase in SARS-CoV-2 antibodies seen with prime dose AstraZeneca vaccine followed by Pfizer-BioNTech

Study: Opioid prescribing preferences, practices among surgical residents and faculty differ

Interleukin-6 antagonists benefit hospitalized patients with COVID-19

Doctors advise against off-label use of new Alzheimer's medicine for cerebral amyloid angiopathy

Plant compounds inhibit Mpro of SARS-CoV-2 and HCoV-229E in vitro

Investigation reveals considerable added benefit of remdesivir for moderately ill COVID-19 patients

Anti-rheumatic drug combinations could reduce the risk of heart attack and strokes

Antibiotic clofoctol shows potential against SARS-CoV-2

Novavax COVID-19 vaccine demonstrates ~90% efficacy against SARS-CoV-2

Study evaluates the difference in weight loss caused by two antidiabetic medications

Study evaluates neutralizing antibody responses elicited by the Pfizer/BioNTech COVID-19 vaccine

Can age, sex, BMI or blood group influence the immunogenicity of the Pfizer/BioNTech COVID-19 vaccine?

COVID-19 vaccines are effective in 94% of cancer patients, shows study

Objective Structured Clinical Examinations can help assess clinical skills of future pharmacists

Individuals who contract COVID-19 after vaccination are likely to have a lower viral load

New article focuses on drug discovery targeting SARS-CoV-2

Ion channel conserved in coronaviruses a potential new drug target for COVID therapeutics

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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