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Tetrodotoxin found in pufferfish can provide potent pain relief when given properly

Opioids remain a mainstay of treatment for chronic and surgical pain, despite their side effects and risk for addiction and overdose.

13 Jun 2019

Weighing risks and benefits of antidepressant medication for older adults

Depression is a common and serious problem for older adults. Some 15 to 20 percent of people aged 65 and older who live independently deal with symptoms of major depressive disorder.

12 Jun 2019

New method produces opiate antidotes using microorganism found in opium poppy waste

Overdose from opiates has skyrocketed. According to the National Center for Health Statistics, on average, 130 Americans die every day from an opioid overdose.

12 Jun 2019

Chemists build rich collection of natural product-like macrocycles for drug discovery

Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class.

12 Jun 2019

Warfarin-treated patients benefit from increasing their vitamin K intake, finds study

When prescribed the anticoagulant drug warfarin, many patients are told to limit foods rich in vitamin K, such as green vegetables.

12 Jun 2019

Researchers find lower opioid prescriptions rates in states that implemented medical cannabis laws

Using data from privately-insured adults, new findings from The University of Texas Medical Branch at Galveston revealed that there is a lower level of opioids prescribed in states that have allowed the use of medical marijuana.

11 Jun 2019

FDA overlooked red flags in drugmaker’s testing of new depression medicine

Ketamine is a darling of combat medics and clubgoers, an anesthetic that can quiet your pain without suppressing breathing and a hallucinogenic that can get you high with little risk of a fatal overdose.

11 Jun 2019

First chemoimmunotherapy regimen approved by FDA for patients with diffuse large B-cell lymphoma

Today, the U.S. Food and Drug Administration granted accelerated approval to Polivy (polatuzumab vedotin-piiq), in combination with the chemotherapy bendamustine and a rituximab product (a combination known as "BR"), to treat adult patients with diffuse large B-cell lymphoma (DLBCL) that has progressed or returned after at least two prior therapies.

10 Jun 2019

Diabetes drug reduces cardiovascular events and kidney problems, study finds

A clinical trial that followed more than 9,900 people in 24 countries has found that the drug dulaglutide reduced cardiovascular events and kidney problems in middle-aged and older people with Type 2 diabetes.

10 Jun 2019

New research provides welcomed news for countless patients taking PPIs

For patients taking proton pump inhibitors to treat gastroesophageal disease (GERD) or other acid-related conditions, new research puts safety concerns to rest.

7 Jun 2019

Still-to-be-approved drug proves to be new option for treating active rheumatoid arthritis

In a large-scale, international study led by renowned rheumatologist Josef Smolen from the Department of Medicine III, a still-to-be-approved drug containing the selective janus kinase inhibitor upadacitinib has proved itself to be a new option for treating active rheumatoid arthritis.

7 Jun 2019

New study examines non‐medical use of anti-anxiety medication

There is concern about the misuse of the sedative anti-anxiety medication alprazolam (Xanax®) because of the "high" it can create.

6 Jun 2019

FDA approves first vaccine for prevention of dengue disease in endemic regions

The U.S. Food and Drug Administration announced today the approval of Dengvaxia, the first vaccine approved for the prevention of dengue disease caused by all dengue virus serotypes (1, 2, 3 and 4) in people ages 9 through 16 who have laboratory-confirmed previous dengue infection and who live in endemic areas.

6 Jun 2019

Antihypertensive drug use linked with reduction in dementia risk

Various clinical trials indicate what effects can be expected from standardized intervention programs on the basis of existing evidence.

3 Jun 2019

Targeted breast cancer therapy shows 'encouraging' results

Researchers have developed a targeted therapy that may significantly increase the survival of pre-menopausal women with advanced breast cancer

3 Jun 2019

Countries' essential medicines lists differ from one another and WHO's model list, study finds

Countries' essential medicines lists vary from one another and from the World Health Organization's model list, pointing to a potential need for greater care in selecting medicines that best meet the health care priorities of a population, suggests a study led by Toronto's St. Michael's Hospital.

3 Jun 2019

Body's endocannabinoid system appears to be new target for drug development against OCD

The body's endocannabinoid system, due to the critical role it plays in regulating neurotransmitter signaling, is an enticing target for drug development against disorders associated with anxiety, stress, and repetitive behaviors, such as obsessive-compulsive disorder.

3 Jun 2019

Study: 81% of antibiotics prescribed by dentists to prevent infections are unnecessary

A new study conducted by researchers at the University of Illinois at Chicago and published in JAMA Network Open has found that 81% of antibiotics prescribed by dentists - who are among the top prescribers in the U.S., accounting for about 10% of all antibiotic prescriptions - to prevent infections prior to dental visits are unnecessary.

31 May 2019

Study links heartburn drugs to fatal cases of heart, kidney disease and gastrointestinal cancer

Extended use of popular drugs to treat heartburn, ulcers and acid reflux has been associated with an increased risk of premature death. However, little has been known about the specific causes of death attributed to the drugs.

30 May 2019

Metabolite of kratom alkaloid could be responsible for its pain relief benefits

Kratom is a Southeast Asian tree with a long history of use in traditional medicine.

30 May 2019

Pharmaceutical News

Tetrodotoxin found in pufferfish can provide potent pain relief when given properly

Weighing risks and benefits of antidepressant medication for older adults

New method produces opiate antidotes using microorganism found in opium poppy waste

Chemists build rich collection of natural product-like macrocycles for drug discovery

Warfarin-treated patients benefit from increasing their vitamin K intake, finds study

Researchers find lower opioid prescriptions rates in states that implemented medical cannabis laws

FDA overlooked red flags in drugmaker’s testing of new depression medicine

First chemoimmunotherapy regimen approved by FDA for patients with diffuse large B-cell lymphoma

Diabetes drug reduces cardiovascular events and kidney problems, study finds

New research provides welcomed news for countless patients taking PPIs

Still-to-be-approved drug proves to be new option for treating active rheumatoid arthritis

New study examines non‐medical use of anti-anxiety medication

FDA approves first vaccine for prevention of dengue disease in endemic regions

Antihypertensive drug use linked with reduction in dementia risk

Targeted breast cancer therapy shows 'encouraging' results

Countries' essential medicines lists differ from one another and WHO's model list, study finds

Body's endocannabinoid system appears to be new target for drug development against OCD

Study: 81% of antibiotics prescribed by dentists to prevent infections are unnecessary

Study links heartburn drugs to fatal cases of heart, kidney disease and gastrointestinal cancer

Metabolite of kratom alkaloid could be responsible for its pain relief benefits

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

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