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Early ovarian removal and APOE4 increase Alzheimer's risk in women

New research published by a team of researchers from the University of Toronto in collaboration with colleagues from the University of Alberta has found that women who have had both ovaries surgically removed before the age of 50 and carry a variant of the apolipoprotein gene, the APOE4 allele, are at high risk of late-life Alzheimer disease (AD). Use of hormone therapy mitigates this risk.

5 Dec 2024

National trial investigates device to restore ovulation in women with PCOS

Physicians at the University of Oklahoma Health Sciences in Oklahoma City are leading a national clinical trial to help women with polycystic ovary syndrome (PCOS)-related infertility who want to become pregnant.

5 Dec 2024

Creatine and resistance workouts combat sarcopenia

Combining creatine supplementation with resistance training boosts muscle strength, lean mass, and cognitive health in older adults, offering a safe and effective strategy against sarcopenia.

4 Dec 2024

Women with infertility have higher risk of developing systemic autoimmune diseases

Women who experience infertility but do not use fertility treatments have a higher risk of developing a group of conditions called systemic autoimmune rheumatic diseases (SARD) in the nine years after a naturally conceived birth compared to women without fertility problems.

4 Dec 2024

Prenatal cfDNA testing uncovers hidden cancers in pregnant individuals

Researchers at the National Institutes of Health (NIH) found previously undetected cancers in 48.6% of pregnant people who had abnormal results for prenatal cell-free DNA (cfDNA) testing used to screen for chromosomal disorders in the fetus.

4 Dec 2024

Women with genetic risk for depression more likely to develop heart disease

Women who have a high genetic risk of depression are more likely to develop heart disease, University of Queensland researchers have found.

4 Dec 2024

New insights into survival of breast cancer cells in the bone marrow

A study from researchers at the University of Michigan and the University of California San Diego has shed light on a previously poorly understood aspect of breast cancer recurrence: how cancer cells survive in bone marrow despite targeted therapies.

4 Dec 2024

Study highlights bias in ACL injury rate metrics for women athletes

A new study by the Harvard GenderSci Lab in the British Journal of Sports Medicine reveals systematic biases in a key metric used in estimates of sex disparities in ACL injury rates in sports.

4 Dec 2024

Biomarker discovery offers hope for aggressive breast cancer treatment

A new study led by Lund University in Sweden has solved a years-old mystery: which patients with aggressive breast cancer are helped by a targeted cancer treatment that had been under development but was shelved.

4 Dec 2024

Mexican American women show highest rates of medication nonadherence after stroke

Women who have had a stroke may be less likely than men to take medications to prevent a second stroke, with Mexican American women reporting the highest rates of nonadherence, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

4 Dec 2024

Transgender women face significantly more injuries than cisgender women

A new study found that injury rates among transgender women are significantly higher than injuries among cisgender women, based on radiological imaging.

4 Dec 2024

UQ researchers and Indigenous students jointly design menstrual health teaching guide

University of Queensland researchers have launched a menstrual health teaching guide for classrooms co-designed with Aboriginal and Torres Strait Islander school students.

3 Dec 2024

Holistic lifestyle interventions outshine drugs in preventing cardiometabolic diseases

Comprehensive lifestyle interventions prevent cardiometabolic diseases effectively but face challenges in routine care and require supportive policies for lasting impact.

3 Dec 2024

Study shows lasting benefits of anti-hormonal therapy in postmenopausal women

Today, women with estrogen-sensitive breast cancer receive anti-hormonal therapy. Researchers now show that postmenopausal women with low-risk tumors have a long-term benefit for at least 20 years, while the benefit was more short-term for younger women with similar tumor characteristics who had not yet gone through the menopause.

3 Dec 2024

Short bursts of vigorous activity may lower cardiovascular risk in women

Short bursts of incidental vigorous physical exertion, lasting less than a minute each, may almost halve the risk of a major cardiovascular event, such as heart attack or heart failure among women who don't exercise regularly, finds research published online in the British Journal of Sports Medicine.

3 Dec 2024