The adrenal glands are the part of the body responsible for releasing three different classes of hormones. These hormones control the "fight or flight" response to stress, maintaining pregnancy, initiating and controlling sexual maturation during childhood and puberty. The adrenal glands are also an important source of sex steroids, such as estrogen and testosterone.
What Does the Adrenal Gland Do?
The adrenal glands are also called suprarenal glands. These are endocrine glands that lie like caps on top of the kidneys.
Glucocorticoids (GCs), or steroids, as they are popularly called, are often prescribed for their anti-inflammatory effects in a host of conditions including acute asthmatic attacks, allergies, and arthritis. However, are they doing good or harm?
For the first time, a study led by researchers at Helmholtz Zentrum München and the German Center for Diabetes Research shows how glucocorticoid hormones, such as cortisol, control sugar and fat levels differently during day and night, feeding and fasting, rest and activity, over the course of 24 hours.
Genes from a virus that was stitched into the human genome thousands of years ago are active, producing proteins in the human brain and other tissues, according to researchers at the University of Washington School of Medicine and the Laval University School of Medicine in Quebec, Canada.
Researchers at the Johns Hopkins Kimmel Cancer Center report that their study of tumor samples from people with the rare genetic syndrome neurofibromatosis type 1 (NF1) has uncovered novel molecular clues about which tumors are most likely to be aggressive in those with NF1
When the adrenal gland produces too much aldosterone, this often leads to high blood pressure and kidney damage (hyperaldosteronism). It has only recently emerged that several patients harbor a mutation in the gene for the ClC-2 chloride channel.
Each year, approximately 750 patients are diagnosed with neuroblastoma in North America, the most common form of cancer in infants less than one year old.
The U.S. Food and Drug Administration today approved Baqsimi nasal powder, the first glucagon therapy approved for the emergency treatment of severe hypoglycemia that can be administered without an injection.
Scientists have discovered a potential biological reason why women are more likely to develop adrenal disorders, including cancer.
Researchers at the University of Alabama at Birmingham and the University of Kansas Cancer Center have identified four hallmarks of cancer metastasis -- when cancer has spread to different parts of the body from where it started. Metastasis is believed to be the cause of up to 90 percent of cancer deaths.
After 20 years, a patient's family received an answer to a decades-long genetic mystery. Their daughter had two rare disorders, Angelman syndrome and P450scc deficiency, which was detected after researchers found out she had uniparental disomy, two copies of chromosome 15 from one parent and none from another.
When DNA in the cell nucleus gets damaged, our cells can resort to a variety of repair mechanisms. A recent study published in 'Nature Cell Biology', to which scientists from Helmholtz Zentrum Muenchen made major contributions, elucidates the molecular basis by which a cell makes the choice between these repair mechanisms.
A low-salt diet may be more beneficial in lowering blood pressure in females than males, report scientists who found that while actual salt retention isn't higher in females, there is still an effect that drives pressure up.
The National Toxicology Program concluded there is clear evidence that male rats exposed to high levels of radio frequency radiation like that used in 2G and 3G cell phones developed cancerous heart tumors, according to final reports released today.
Two academics from Queen Mary University of London have received prestigious awards from the International Society of Hypertension 2018 in recognition of their achievements in blood pressure research.
Physician researchers with The Ohio State University College of Medicine at the Wexner Medical Center say increased levels of the hormone aldosterone, already associated with hypertension, can play a significant role in the development of diabetes, particularly among certain racial groups.
The U.S. Food and Drug Administration has approved the first ever non-surgical treatment for the rare neuroendocrine cancers pheochromocytoma and paraganglioma.
The U.S. Food and Drug Administration today approved Azedra (iobenguane I 131) injection for intravenous use for the treatment of adults and adolescents age 12 and older with rare tumors of the adrenal gland (pheochromocytoma or paraganglioma) that cannot be surgically removed (unresectable), have spread beyond the original tumor site and require systemic anticancer therapy.
A radiotherapy drug that treats the rare neuroendocrine cancers pheochromocytoma and paraganglioma can be both effective and safe for patients, according to the findings of a multi-center trial led by researchers in the Abramson Cancer Center of the University of Pennsylvania.
Just as a runner steadily builds up endurance in order to peak at just the right time, the placenta carefully calibrates how much of the hormone allopregnanolone it produces during pregnancy.
A new study has definitively shown that a single treatment with gene therapy using adeno-associated viral (AAV) vector gene delivery to replace the defective gene responsible for congenital adrenal hyperplasia (CAH) will only temporarily alleviate the hereditary disorder.