Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

New UA research reveals factors that can impact aging adults' quality of life

As the world's population of older adults increases, so do conversations around successful aging -- including seniors' physical, mental and social well-being.

2 Jun 2015

Key lifestyle changes could help reduce risk of cognitive decline

The evidence is mounting: People can reduce their risk of cognitive decline by making key lifestyle changes. That is the conclusion of a new research summary published online today in Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

1 Jun 2015

New data on Resverlogix RVX-208 for CKD treatment presented at ERA-EDTA Congress

Resverlogix Corp. today announced that new data on RVX-208 was presented at the ERA-EDTA Congress in London, England in a poster entitled: "Effects of RVX-208, a First-in-Class Epigenetic BET-Inhibitor, on Key Renal Parameters in Subjects with a History of CVD, and Chronic Kidney Disease (CKD); a Post-hoc Analysis of Patients from the ASSERT, SUSTAIN and ASSURE Clinical Trials."

1 Jun 2015

Lenvatinib-everolimus combination extends PFS in patients with mRCC versus everolimus alone

Eisai Inc. announced today results from an investigational Phase 2 trial which showed that lenvatinib, when used in combination with everolimus, significantly extended progression-free survival (PFS) in patients with metastatic renal cell carcinoma (mRCC) versus everolimus alone.

1 Jun 2015

Premature mortality target highly unethical and explicitly ageist

One of the main health targets proposed by the UN Sustainable Development Goals (SDG) is to reduce by one-third premature mortality from non-communicable diseases such as cancer, stroke and dementia. The goals for 2016-2030 define premature mortality as deaths occurring among people aged 69 years old or younger.

1 Jun 2015

Precision medicine helps improve patient health and reduces risk of side effects, says Penn Medical School dean

The rapidly emerging field of precision medicine is a "disruptive innovation" that offers the possibility of remarkably fine-tuned remedies to improve patient health while minimizing the risk of harmful side effects, says J. Larry Jameson, MD, PhD, dean of the Perelman School of Medicine and executive vice president of the University of Pennsylvania for the Health System, in this week's issue of the New England Journal of Medicine.

1 Jun 2015

Eisai Phase 3 trial of eribulin meets primary endpoint in patients with advanced soft tissue sarcoma

Eisai Inc. announced today the results of its Phase 3 trial (Study 309), which showed that eribulin met the study's primary endpoint evaluating overall survival in patients who had advanced leiomyosarcoma (LMS) or adipocytic sarcoma (ADI), two types of advanced soft tissue sarcoma.

30 May 2015

Iron may underlie effect of Alzheimer’s risk allele

Ferritin in the cerebrospinal fluid of patients with Alzheimer’s disease is associated with the APOE ε4 risk allele and predicts cognitive outcomes, a study shows.

29 May 2015

People with cognitive impairment have altered responses to pain

People with dementia and other forms of cognitive impairment (CI) have altered responses to pain, with many conditions associated with increased pain sensitivity, concludes a research review in PAIN, the official publication of the International Association for the Study of Pain.

29 May 2015

Main culprit of Alzheimer's disease causes memory loss

The study, published May 29 in the open access Nature Publishing Group journal Scientific Reports, reveals a direct link between the main culprit of Alzheimer's disease and memory loss.

29 May 2015

RI-MUHC researchers receive $1.5 million to develop glutamate biosensor platform for brain diseases

In the human brain and retina, glutamate is an important messenger that carries information from one neuron to another. The level of glutamate transmitted between neurons is crucial to cell communication: too high and neurons die, too low and the information is not communicated properly. In either case this can contribute to neurological diseases including stroke, glaucoma, and Alzheimer's.

29 May 2015

Hearing impairment more prevalent among Hispanic/Latino adults

Hearing impairment was more prevalent among men and older individuals in a study of U.S. Hispanic/Latino adults, according to a report published online by JAMA Otolaryngology-Head and Neck Surgery.

29 May 2015

People with MS have much greater risk of dying younger compared to people without MS

New research suggests people with multiple sclerosis (MS) may have double the risk of dying early compared to people without MS, with those younger than 59 at a three times higher risk. The study is published in the May 27, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 May 2015

Data supporting anti-cancer potential of Biscayne’s GHRH antagonist to be discussed at ASCO Annual Meeting

Biscayne Pharmaceuticals, Inc., today announced that data supporting the anti-cancer potential of its growth hormone-releasing hormone (GHRH) technology will be discussed in a poster presentation at the 2015 ASCO Annual Meeting.

28 May 2015

Diabetes and poor diet can trigger Alzheimer's or Parkinson's, warns BUAP researcher

For several years a researcher was dedicated to feed rodents in his laboratory with a high caloric content and glucose concentrations, which caused them diabetes, and by scientifically assessing what occurred in animals he observed that "diabetes and poor diet is a risk factor for developing Alzheimer's or Parkinson's," warns Samuel Treviño Mora from the Meritorious University of Puebla in Mexico.

28 May 2015

Six research teams awarded grant to accelerate discovery of new drugs for brain, nervous system disorders

CQDM, Brain Canada and the Ontario Brain Institute award close to $8.5M to six (6) multi-disciplinary and multi-provincial research teams across Canada to address unmet needs in neuroscience within their Focus on Brain strategic initiative. To this amount, $1.5M is added from the various research entities involved as in-kind contributions.

27 May 2015

UC San Diego Health System designated as Center of Excellence for Huntington's disease

The Huntington's Disease Clinical Research Center at UC San Diego Health System has been designated a Center of Excellence by the Huntington's Disease Society of America. UC San Diego was one of only 29 centers nationwide to receive this prestigious designation, which recognizes centers for their elite multidisciplinary approach to Huntington's disease care and research.

27 May 2015

New in vitro system could become important tool in search for potential drugs against Alzheimer’s

A typical characteristic of the brain of an Alzheimer sufferer is the presence of insoluble Tau protein aggregates. Scientists at VIB, KU Leuven and Janssen Pharmaceutica have demonstrated that the distribution of these aggregates through the brain is facilitated by synaptic connections between brain cells.

26 May 2015

Previous motherhood alters cognition, neuroplasticity in response to hormone therapy

Hormone therapy (HT) is prescribed to alleviate some of the symptoms of menopause in women. Menopausal women are more likely to be diagnosed with Alzheimer's disease but not other forms of dementia, and HT has been prescribed to treat cognitive decline in post-menopausal women with variable degrees of effectiveness.

26 May 2015

New article shows link between head injuries and neurodegenerative disease in rugby union players

A new article publishing online today in the Quarterly Journal of Medicine has reported the first case showing an association between exposure to head injuries in rugby union players and an increased risk in neurodegenerative disease.

24 May 2015

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

New UA research reveals factors that can impact aging adults' quality of life

Key lifestyle changes could help reduce risk of cognitive decline

New data on Resverlogix RVX-208 for CKD treatment presented at ERA-EDTA Congress

Lenvatinib-everolimus combination extends PFS in patients with mRCC versus everolimus alone

Premature mortality target highly unethical and explicitly ageist

Precision medicine helps improve patient health and reduces risk of side effects, says Penn Medical School dean

Eisai Phase 3 trial of eribulin meets primary endpoint in patients with advanced soft tissue sarcoma

Iron may underlie effect of Alzheimer’s risk allele

People with cognitive impairment have altered responses to pain

Main culprit of Alzheimer's disease causes memory loss

RI-MUHC researchers receive $1.5 million to develop glutamate biosensor platform for brain diseases

Hearing impairment more prevalent among Hispanic/Latino adults

People with MS have much greater risk of dying younger compared to people without MS

Data supporting anti-cancer potential of Biscayne’s GHRH antagonist to be discussed at ASCO Annual Meeting

Diabetes and poor diet can trigger Alzheimer's or Parkinson's, warns BUAP researcher

Six research teams awarded grant to accelerate discovery of new drugs for brain, nervous system disorders

UC San Diego Health System designated as Center of Excellence for Huntington's disease

New in vitro system could become important tool in search for potential drugs against Alzheimer’s

Previous motherhood alters cognition, neuroplasticity in response to hormone therapy

New article shows link between head injuries and neurodegenerative disease in rugby union players

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

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