Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Discovery paves way for developing treatments for people addicted to cocaine, amphetamines

In a major advance in the field of neuropsychiatry, researchers in the Vollum Institute at Oregon Health & Science University have illuminated how cocaine and amphetamines disrupt the normal functioning of the dopamine transporter in the brain.

12 May 2015

Study finds link between PTSD and accelerated aging

In recent years, public health concerns about post-traumatic stress disorder (PTSD) have risen significantly, driven in part by affected military veterans returning from conflicts in the Middle East and elsewhere. PTSD is associated with number of psychological maladies, among them chronic depression, anger, insomnia, eating disorders and substance abuse.

10 May 2015

β-amyloid deposition highly variable in synucleinopathy

A meta-analysis suggests large variability in the prevalence of β-amyloid deposition in patients with synucleinopathies.

8 May 2015

Creating digital technology prototypes to improve dementia care

A health-inspired hackathon is taking place in Newcastle-Upon-Tyne, UK, with the aim of creating digital technology prototypes to support dementia care. Designers, coders, hackers and researchers are invited to take part in Create-4-Dementia on May 30th and 31st - the first public event of the Social Computing and Mental Health Research Network led by the University of Lincoln, UK, and funded by the Engineering and Physical Sciences Research Council.

8 May 2015

Knowing the physical structure of amyloid beta-42 offers new view on amyloid propagation in Alzheimer's

Researchers at the University of Illinois at Chicago have determined the molecular structure of one of the proteins in the fine fibers of the brain plaques that are a hallmark of Alzheimer's disease. This molecule, called amyloid beta-42, is toxic to nerve cells and is believed to provoke the disease cascade.

8 May 2015

GTEx findings reveal how genomic variants can affect gene activity and disease susceptibility

Researchers funded by the National Institutes of Health Genotype-Tissue Expression (GTEx) project have created a new and much-anticipated data resource to help establish how differences in an individual's genomic make-up can affect gene activity and contribute to disease.

8 May 2015

Roll-out of eMR-ABC software in Indiana may benefit older adults with dementia or depression

Older Indiana adults with dementia or depression will be among the best cared for elders in the nation beginning this month with the statewide roll-out of a unique automated decision-support system that enables their care coordinators to meet the complex bio-psychosocial needs of these individuals as well as those of their family members and other informal caregivers.

8 May 2015

NIH-sponsored Phase 1 clinical trial evaluates novel investigational West Nile virus vaccine

A novel investigational West Nile virus vaccine discovered and developed by scientists at the Oregon National Primate Research Center at Oregon Health & Science University is being evaluated in an NIH-sponsored Phase 1, first-in-human, clinical trial at Duke University. Although several early-stage West Nile virus vaccine clinical trials have been completed to date, no human vaccine has been approved for commercial use.

7 May 2015

New epilepsy drug holds promise as Alzheimer's treatment

University of British Columbia researchers say a new epilepsy drug holds promise as a treatment for Alzheimer's disease.

7 May 2015

Wearable cognitive assessment devices a step closer as Cambridge Cognition file new patents

The combination of bio-behavioural measures and results from touch-screen cognitive tests would be used to build up a picture of a person’s mental function...

7 May 2015

Transition Therapeutics acquires worldwide rights from Lilly to develop, commercialize TT701

Transition Therapeutics Inc. today announced its wholly-owned subsidiary, Transition Therapeutics Ireland Limited, has exclusively licensed worldwide rights to a novel small molecule drug candidate ("TT701") from Eli Lilly and Company.

6 May 2015

Ground-breaking study characterizes early-stage Alzheimer's abnormalities in the intact brain

Alzheimer's disease (AD) is a neurodegenerative condition that strikes at the heart of what makes us human: the ability to think, to feel, to remember and to communicate with those around us. The tragedy is compounded by the fact that there is currently no cure, no treatment, and no diagnostic method capable of identifying Alzheimer's at its early stages.

6 May 2015

Proteomics helps identify previously unrecognized proteins and pathways in nerve regeneration

Using proteomics techniques to study injured optic nerves, researchers at Boston Children's Hospital have identified previously unrecognized proteins and pathways involved in nerve regeneration. Adding back one of these proteins--the oncogene c-myc--they achieved unprecedented optic nerve regeneration in mice when combined with two other known strategies.

5 May 2015

Researchers uncover new connection between Alzheimer's disease and diabetes

Researchers have uncovered a unique connection between diabetes and Alzheimer's disease, providing further evidence that a disease that robs people of their memories may be affected by elevated blood sugar, according to scientists at Washington University School of Medicine in St. Louis.

5 May 2015

Green tea compound, voluntary exercise slow Alzheimer's disease progression in mice

According to the National Institutes of Health, Alzheimer's disease (AD) may affect as many as 5.5 million Americans. Scientists currently are seeking treatments and therapies found in common foods that will help stave off the disease or prevent it completely.

5 May 2015

Predominant first Alzheimer’s symptoms vary with diagnosis age

The symptoms presented by patients newly diagnosed with Alzheimer’s disease vary with age, with younger patients less likely to have initial memory problems, research shows.

30 Apr 2015

Promising compound blocks production of beta amyloid peptides in Alzheimer's mouse model

Offering a potential early intervention for Alzheimer's disease (AD), researchers at University of California, San Diego School of Medicine and Cenna Biosciences, Inc. have identified compounds that block the production of beta amyloid peptides in mice.

30 Apr 2015

New study finds that challenging work tasks may have significant effect on brain health

Professionals whose jobs require more speaking, developing strategies, conflict resolution and managerial tasks may experience better protection against memory and thinking decline in old age than their co-workers, according to a new study published in the April 29, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

30 Apr 2015

Parents share arduous, circuitous journey to get referrals for childhood epilepsy surgery

Having a child diagnosed with epilepsy can be a frightening and confusing time. Now, parents share their arduous and "circuitous" journey to get referrals for pediatric epilepsy surgery once their child's disease stops responding to anti-seizure medications. The UCLA study sheds light on the difficulties parents face obtaining specialty and sub-specialty care for their children during an already stressful time.

30 Apr 2015

1 in 5 nursing home residents with dementia harbor strains of drug-resistant bacteria

A new study found one in five nursing home residents with advanced dementia harbor strains of drug-resistant bacteria and more than 10 percent of the drug-resistant bacteria are resistant to four or more antibiotic classes. The research was published online today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

30 Apr 2015

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Discovery paves way for developing treatments for people addicted to cocaine, amphetamines

Study finds link between PTSD and accelerated aging

β-amyloid deposition highly variable in synucleinopathy

Creating digital technology prototypes to improve dementia care

Knowing the physical structure of amyloid beta-42 offers new view on amyloid propagation in Alzheimer's

GTEx findings reveal how genomic variants can affect gene activity and disease susceptibility

Roll-out of eMR-ABC software in Indiana may benefit older adults with dementia or depression

NIH-sponsored Phase 1 clinical trial evaluates novel investigational West Nile virus vaccine

New epilepsy drug holds promise as Alzheimer's treatment

Wearable cognitive assessment devices a step closer as Cambridge Cognition file new patents

Transition Therapeutics acquires worldwide rights from Lilly to develop, commercialize TT701

Ground-breaking study characterizes early-stage Alzheimer's abnormalities in the intact brain

Proteomics helps identify previously unrecognized proteins and pathways in nerve regeneration

Researchers uncover new connection between Alzheimer's disease and diabetes

Green tea compound, voluntary exercise slow Alzheimer's disease progression in mice

Predominant first Alzheimer’s symptoms vary with diagnosis age

Promising compound blocks production of beta amyloid peptides in Alzheimer's mouse model

New study finds that challenging work tasks may have significant effect on brain health

Parents share arduous, circuitous journey to get referrals for childhood epilepsy surgery

1 in 5 nursing home residents with dementia harbor strains of drug-resistant bacteria

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

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