Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Mayo Clinic scientists create mouse model of ALS, FTD caused by mutations in C9ORF72 gene

Scientists at Mayo Clinic, Jacksonville, Florida created a novel mouse that exhibits the symptoms and neurodegeneration associated with the most common genetic forms of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), both of which are caused by a mutation in the a gene called C9ORF72.

24 May 2015

Decreased removal of toxic peptides causes onset of Alzheimer's disease

Jens Pahnke and his team at the University of Oslo has recently published results in the prestigious scientific journal 'BRAIN' showing that decreased removal of toxic peptides in the brain causes the onset and first clinical signs of Alzheimer's disease, rather than overproduction as has previously been assumed. This information can now be used to target specific genes to enhance their function in the brain of elderly or people at risk.

22 May 2015

Studies refine amyloid imaging role in dementia

Two meta-analyses published in JAMA help to define the role of amyloid imaging in dementia.

21 May 2015

Certain proteins may slow cognitive decline in people with Alzheimer's disease

Certain proteins may slow the devastating memory loss caused by Alzheimer's disease, according to a groundbreaking Iowa State University study.

21 May 2015

New study shows that infections can affect cognitive ability

New research shows that infections can impair your cognitive ability measured on an IQ scale. The study is the largest of its kind to date, and it shows a clear correlation between infection levels and impaired cognition.

21 May 2015

Available research does not support link between chronic traumatic encephalopathy and sports

Available research does not support the contention that athletes are uniquely at risk of chronic traumatic encephalopathy (CTE) or other neurodegenerative disorders, according to a review in the June issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

21 May 2015

HQO report shows variations across Ontario's long-term care homes regarding antipsychotic drug use

There are major differences across Ontario's long-term care homes in the percentage of residents who are being prescribed antipsychotic medications, according to Looking for Balance, a report from Health Quality Ontario, the provincial advisor on health care quality.

20 May 2015

Omega-3 fatty acids improve cognitive flexibility in older adults at risk of late-onset Alzheimer's disease

A study of older adults at risk of late-onset Alzheimer's disease found that those who consumed more omega-3 fatty acids did better than their peers on tests of cognitive flexibility -- the ability to efficiently switch between tasks -- and had a bigger anterior cingulate cortex, a brain region known to contribute to cognitive flexibility.

20 May 2015

vTv Therapeutics enrolls first patients in azeliragon Phase 3 trial for treatment of mild Alzheimer's disease

vTv Therapeutics LLC today announced enrollment of the first patients into STEADFAST (Single Trial Evaluating Alzheimer's Disease Following Addition to Symptomatic Therapy), vTv's Phase 3 placebo controlled trial of azeliragon, an oral antagonist of the Receptor for Advanced Glycation Endproducts (RAGE) for treatment of mild Alzheimer's disease.

19 May 2015

Study: Air pollution, impaired lung function independently affect cognition

Studies have shown that both air pollution and impaired lung function can cause cognitive deficits, but it was unclear whether air pollution diminishes cognition by reducing breathing ability first or whether air pollution represents an independent risk factor for cognitive deficit.

19 May 2015

Grass plants can bind, uptake and transport infectious prions

Grass plants can bind, uptake and transport infectious prions, according to researchers at The University of Texas Health Science Center at Houston (UTHealth).

18 May 2015

New findings could help better understand neurodegenerative diseases

Researchers at the Luxembourg Centre for Systems Biomedicine (LCSB), of the University of Luxembourg, have, under Dr. Manuel Buttini, successfully measured metabolic profiles, or the metabolomes, of different brain regions, and their findings could help better understand neurodegenerative diseases.

18 May 2015

Research leads way for noninvasive detection of early stage liver cancer

Led by Georgia State University, researchers have developed the first robust and noninvasive detection of early stage liver cancer and liver metastases, in addition to other liver diseases, such as cirrhosis and liver fibrosis.

15 May 2015

Researchers explore how low-level electrical stimulation reduces inflammation

The Feinstein Institute for Medical Research, the research arm of the North Shore-LIJ Health System, and SetPoint Medical Inc., a biomedical technology company, today released the results of research on the therapeutic potential of vagus nerve stimulation. In a paper published by Bioelectronic Medicine, Kevin J. Tracey, MD, and his colleagues at the Feinstein Institute, explore how low-level electrical stimulation interacts with the body's nerves to reduce inflammation, a fundamental goal of bioelectronic medicine.

15 May 2015

Denali launched to discover, develop effective medicines for neurodegenerative diseases

Denali Therapeutics Inc., a new biotechnology company focused on developing effective therapies for neurodegenerative diseases, announced today that it has launched with an initial investment commitment of $217 million.

14 May 2015

Growth of neuronal and vascular networks is controlled by same signaling molecules

Neurons and blood vessels often traverse the body side by side, a fact observed as early as the 16th century by the Flemish anatomist Andreas Vesalius. Only over the last ten years, however, researchers have discovered that the growth of neuronal and vascular networks is controlled by the same molecules.

14 May 2015

New work challenges long-held beliefs about link between hippocampus and improved memory function

New work by the Douglas Mental Health University Institute (CIUSSS de l'Ouest-de-l'île-de-MontréalI) computational neuroscientist Mallar Chakravarty, PhD, and in collaboration with researchers at the Centre for Addiction and Mental Health challenges in a thrilling way the long-held belief that a larger hippocampus is directly linked to improved memory function.

14 May 2015

Eating Mediterranean diet helps delay cognitive decline

Professor of Preventive Medicine at the University of Valencia Dolors Corella is part of the multidisciplinary team conducting the Predimed study, which has found that eating a Mediterranean diet, enriched with olive oil or nuts, helps delay cognitive decline.

13 May 2015

Repetitive head injuries may accelerate aging process, increase dementia risk

Repetitive head injuries that occur during contact sports and military service may accelerate the aging process by increasing the build-up of beta-amyloid in the brain, leading to worse disease and an increased likelihood of developing dementia. In particular, boxers fared the worst among athletes and military veterans with a history of head injuries.

13 May 2015

Discovery paves way for developing treatments for people addicted to cocaine, amphetamines

In a major advance in the field of neuropsychiatry, researchers in the Vollum Institute at Oregon Health & Science University have illuminated how cocaine and amphetamines disrupt the normal functioning of the dopamine transporter in the brain.

12 May 2015

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Mayo Clinic scientists create mouse model of ALS, FTD caused by mutations in C9ORF72 gene

Decreased removal of toxic peptides causes onset of Alzheimer's disease

Studies refine amyloid imaging role in dementia

Certain proteins may slow cognitive decline in people with Alzheimer's disease

New study shows that infections can affect cognitive ability

Available research does not support link between chronic traumatic encephalopathy and sports

HQO report shows variations across Ontario's long-term care homes regarding antipsychotic drug use

Omega-3 fatty acids improve cognitive flexibility in older adults at risk of late-onset Alzheimer's disease

vTv Therapeutics enrolls first patients in azeliragon Phase 3 trial for treatment of mild Alzheimer's disease

Study: Air pollution, impaired lung function independently affect cognition

Grass plants can bind, uptake and transport infectious prions

New findings could help better understand neurodegenerative diseases

Research leads way for noninvasive detection of early stage liver cancer

Researchers explore how low-level electrical stimulation reduces inflammation

Denali launched to discover, develop effective medicines for neurodegenerative diseases

Growth of neuronal and vascular networks is controlled by same signaling molecules

New work challenges long-held beliefs about link between hippocampus and improved memory function

Eating Mediterranean diet helps delay cognitive decline

Repetitive head injuries may accelerate aging process, increase dementia risk

Discovery paves way for developing treatments for people addicted to cocaine, amphetamines

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

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