Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Protein complex plays critical role in development of Alzheimer's disease

The Bonn site of the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn are leading contributors.

21 Dec 2012

Exercise and mental health: an interview with Professor Nanette Mutrie

Perhaps we should first of all clear up the definition of exercise. In public health terms it is more common to use the phrase ‘physical activity’ because this phrase encompasses all kinds of movement- indeed anything we do above sitting and resting levels.

21 Dec 2012

UCLA study assesses prevalence of various types of study partners in Alzheimer's trials

For Alzheimer's disease researchers who conduct clinical trials, enrolling enough patients to make a trial meaningful is always a challenge. To enroll a single patient in a study requires not one but two participants - the patient and what's known as a study partner. Study partners provide the patient with support and update researchers about the patient's progress.

21 Dec 2012

Study identifies mechanisms responsible for regenerating blood vessels in the brain

New research from the University of Georgia identifies the mechanisms responsible for regenerating blood vessels in the brain.

20 Dec 2012

Study finds new signaling pathway involved in development of chronic inflammation of brain cells

The number of Alzheimer's patients will continue to dramatically increase in the next several decades. Various teams of researchers worldwide are feverishly investigating precisely how the illness develops. A

20 Dec 2012

FUS RNA binding ability essential for development of Amyotrophic Lateral Sclerosis

Research led by Dr. Udai Pandey, Assistant Professor of Genetics at LSU Health Sciences Center New Orleans, has found that the ability of a protein made by a gene called FUS to bind to RNA is essential to the development of Amyotrophic Lateral Sclerosis (ALS). This discovery identifies a possible therapeutic target for the fatal neurological disease.

20 Dec 2012

Scientists uncover TDP-43 protein as possible target for treatment of ALS, FTD

Neuroscientists at Georgetown University Medical Center say they have new evidence that challenges scientific dogma involving two fatal neurodegenerative diseases - amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD) - and, in the process, have uncovered a possible therapeutic target as a novel strategy to treat both disorders.

20 Dec 2012

Positive top-line results from Idera’s IMO-3100 Phase 2a trial on plaque psoriasis

Idera Pharmaceuticals today announced that 48% of patients with moderate-to-severe plaque psoriasis (12 of 25) treated with IMO-3100, a selective antagonist of Toll-like Receptors (TLRs) 7 and 9, demonstrated improvements in Psoriasis Area Severity Index (PASI) scores of 35% to 90% from baseline at the completion of a randomized, double-blind, placebo-controlled Phase 2a clinical trial of two dose levels of IMO-3100 administered for four weeks, with a four-week follow-up period.

20 Dec 2012

Clock is ticking for insurance exchange implementation

The idea of a health insurance exchange as laid out in President Barack Obama's signature law seems straightforward: an online marketplace where people will shop for private health insurance, like buying an airline ticket or a hotel room.

19 Dec 2012

Calif. advocates worry court-OK'd payment reductions will make it harder for poor to get care

Some worry that a Medicaid expansion in California could be hampered by reduced payments to Medi-Cal providers that a court approved last week, making it more difficult for the poor to find specialists.

18 Dec 2012

Blocking single tiny blood vessel in the brain can harm neural tissue and even alter behavior

Blocking a single tiny blood vessel in the brain can harm neural tissue and even alter behavior, a new study from the University of California, San Diego has shown. But these consequences can be mitigated by a drug already in use, suggesting treatment that could slow the progress of dementia associated with cumulative damage to miniscule blood vessels that feed brain cells.

17 Dec 2012

Three critical illness factors independently associated with increased risk of dementia

Older people often worry about dementia and while some risks are known, for example alcoholism or stroke, the effects of illness are less clear. New research published in BioMed Central's open access journal Critical Care looks at illness requiring hospitalization and treatment in the intensive care unit (ICU) and finds that infection or severe sepsis, neurological dysfunction, such as delirium, or acute dialysis are all independently associated with an increased risk of a subsequent diagnosis of dementia.

17 Dec 2012

Cognitive test used in Alzheimer's drug trials is flawed: Study

New research led by Plymouth University Peninsula Schools of Medicine and Dentistry suggests that the cognitive test used in Alzheimer's drug trials is flawed.

16 Dec 2012

States getting arms around Medicaid expansion, challenges in own Medicaid programs

The health law's treatment of using Medicaid to expand coverage to more Americans is examined in Georgia -- where a doctor pay raise in the program has stirred discontent -- and in Oregon, where 200,000 stand to qualify under the program's expansion.

15 Dec 2012

Research provides broader understanding of processes that lead to Alzheimer's disease

Alzheimer's disease is the most common form of dementia, affecting over 35 million people worldwide. It is generally assumed that the clumping of beta-amyloid (Aβ) protein causes neuronal loss in patients.

15 Dec 2012

MDx, Amarantus sign license agreement for LymPro Alzheimer's disease diagnostic blood test

Amarantus BioScience, Inc., a biotechnology company discovering and developing treatments for diseases associated with protein misfolding and apoptosis, today announced that it has licensed the LymPro Alzheimer's Disease Diagnostic Blood Test (LymPro) from Memory Dx, LLC (MDx), formerly known as Provista Life Sciences, Inc.

14 Dec 2012

Survey finds serious shortfalls in quality of mental health care for older adults

Large majorities of older Americans with depression, anxiety, or other mental health disorders are receiving treatment that does not meet evidence-based standards, and many do not know that depression can put their health at increased risk, according to a national survey, "Silver and Blue: The Unfinished Business of Mental Health Care for Older Adults," released today by the John A. Hartford Foundation.

13 Dec 2012

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Protein complex plays critical role in development of Alzheimer's disease

Exercise and mental health: an interview with Professor Nanette Mutrie

UCLA study assesses prevalence of various types of study partners in Alzheimer's trials

Study identifies mechanisms responsible for regenerating blood vessels in the brain

Study finds new signaling pathway involved in development of chronic inflammation of brain cells

FUS RNA binding ability essential for development of Amyotrophic Lateral Sclerosis

Scientists uncover TDP-43 protein as possible target for treatment of ALS, FTD

Positive top-line results from Idera’s IMO-3100 Phase 2a trial on plaque psoriasis

Clock is ticking for insurance exchange implementation

Calif. advocates worry court-OK'd payment reductions will make it harder for poor to get care

Blocking single tiny blood vessel in the brain can harm neural tissue and even alter behavior

Three critical illness factors independently associated with increased risk of dementia

Cognitive test used in Alzheimer's drug trials is flawed: Study

States getting arms around Medicaid expansion, challenges in own Medicaid programs

Research provides broader understanding of processes that lead to Alzheimer's disease

MDx, Amarantus sign license agreement for LymPro Alzheimer's disease diagnostic blood test

Survey finds serious shortfalls in quality of mental health care for older adults

Eli Lilly provides update on solanezumab Phase 3 clinical study for mild Alzheimer's

Scientists determine specific genetic switches that sync liver activity to the circadian cycle

Activated astrocytes could play a harmful role in Alzheimer's disease

Innovation in neuroscience drug discovery - eBook eBook

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Innovation in neuroscience drug discovery - eBook eBook

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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