Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Shortage of TDP-43 protein causes muscle wasting and stunted nerve cells

A shortage of a protein called TDP-43 caused muscle wasting and stunted nerve cells. This finding supports the idea that malfunction of this protein plays a decisive role in ALS and FTD. The study is published in the "Proceedings of the National Academy of Sciences of the USA" (PNAS).

3 Mar 2013

Oxford researcher wins 2013 John Dystel Prize from AAN, National Multiple Sclerosis Society

The American Academy of Neurology and the National Multiple Sclerosis Society are awarding the 2013 John Dystel Prize for MS Research to George C. Ebers, MD, a leading researcher with the University of Oxford and Oxford University Hospitals Trust in Oxford, United Kingdom.

2 Mar 2013

Researchers identify novel signaling pathway responsible for neuroprotective activity of parkin

Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich identify a novel signal transduction pathway, which activates the parkin gene and prevents stress-induced neuronal cell death.

2 Mar 2013

AAN to award 2013 Michael S. Pessin Stroke Leadership Prize to Amytis Towfighi

The American Academy of Neurology is awarding the 2013 Michael S. Pessin Stroke Leadership Prize to Amytis Towfighi, MD, with the University of Southern California and Rancho Los Amigos National Rehabilitation Center for her research in post-stroke preventive care.

2 Mar 2013

Remembering proper eating habits can improve physical health and reduce depression

A new analysis has found that a combination of methods that help patients with dementia remember proper eating habits can improve their physical health and lessen symptoms of depression.

1 Mar 2013

Otsuka receives FDA approval for ABILIFY MAINTENA to treat schizophrenia

Otsuka Pharmaceutical Co., Ltd. (Otsuka) and H. Lundbeck A/S (Lundbeck) announced the U.S. Food and Drug Administration (FDA) has approved ABILIFY MAINTENA (aripiprazole) for extended- release injectable suspension, an intramuscular (IM) depot formulation indicated for the treatment of schizophrenia.

1 Mar 2013

Researchers develop new genetically altered mice that model earliest stages of Alzheimer's

Researchers at the University of Florida and The Johns Hopkins University have developed a line of genetically altered mice that model the earliest stages of Alzheimer's disease. This model may help scientists identify new therapies to provide relief to patients who are beginning to experience symptoms.

1 Mar 2013

Amyloid plaques take about 15 years to build up and then plateau: Study

Researchers have identified a possible treatment window of several years for plaques in the brain that are thought to cause memory loss in diseases such as Alzheimer's. The Mayo Clinic study is published in the Feb. 27 online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Feb 2013

Jones & Bartlett Learning publishes 'Introduction to Neurogenic Communication Disorders'

M. Hunter Manasco, Ph.D., C.C.C.-S.L.P., assistant professor of speech-language pathology at Misericordia University, has had the textbook and video combination, "Introduction to Neurogenic Communication Disorders,'' published by Jones & Bartlett Learning.

28 Feb 2013

Proper eating habits in dementia patients can improve their physical health and lessen symptoms of depression

A new analysis has found that a combination of methods that help patients with dementia remember proper eating habits can improve their physical health and lessen symptoms of depression. Published early online in the Journal of Advanced Nursing, the study indicates that clinicians should consider using this intervention in individuals with dementia who also have poor nutrition and signs of depression.

28 Feb 2013

Researchers to discuss health issues at Society of Toxicology's Annual Meeting and ToxExpo

Researchers will meet at the Society of Toxicology's Annual Meeting and ToxExpo March 10-16 to discuss a number of health concerns that have received growing public attention over the past several months.

27 Feb 2013

MID1 complex binds with messenger RNA and controls synthesis of defective Huntingtin

Huntington's disease, also known as Huntington's chorea, is a hereditary brain disease causing movement disorders and dementia. In Germany, there are about 8,000 patients affected by Huntington's disease, with several hundred new cases arising every year. The disease usually manifests between the ages of 35 and 50.

27 Feb 2013

Researchers discover novel way to image the entire brain's glymphatic pathway

A novel way to image the entire brain's glymphatic pathway, a dynamic process that clears waste and solutes from the brain that otherwise might build-up and contribute to the development of Alzheimer's disease, may provide the basis for a new strategy to evaluate disease susceptibility, according to a research paper published online in The Journal of Clinical Investigation.

26 Feb 2013

WUSTL to develop 3-D computer models of brain biomechanics to better understand TBI

Washington University in St. Louis engineering researchers have received a five-year, $2.25 million grant to better understand traumatic brain injuries in efforts to improve methods for prevention and treatment.

25 Feb 2013

Researchers identify several genes associated with human neurological disorders

Scientists at the Marine Biological Laboratory (MBL) have identified several genes linked to human neurological disorders, including Alzheimer's disease, Parkinson's disease and spinal cord injury, in the sea lamprey, a vertebrate fish whose whole-genome sequence is reported this week in the journal Nature Genetics.

25 Feb 2013

Major doctor group coalition expands list of tests, treatments that should be done only rarely

The American Board of Internal Medicine, as part of its "Choosing Wisely" campaign, expanded the number of medical societies recommending caution before certain tests and procedures are ordered.

22 Feb 2013

Targeting CSF1R with selective inhibitors could help Alzheimer's

Scientists from the University of Southampton have identified the molecular system that contributes to the harmful inflammatory reaction in the brain during neurodegenerative diseases.

22 Feb 2013

Researchers use familial and sporadic patient-derived iPSCs to model Alzheimer's disease

Working with a group from Nagasaki University, a research group at the Center for iPS Cell Research and Application (CiRA) at Japan's Kyoto University has announced in the Feb. 21 online publication of Cell Stem Cell has successfully modeled Alzheimer's disease (AD) using both familial and sporadic patient-derived induced pluripotent stem cells (iPSCs), and revealed stress phenotypes and differential drug responsiveness associated with intracellular amyloid beta oligomers in AD neurons and astrocytes.

21 Feb 2013

Resveratrol may protect against hearing and cognitive decline

Resveratrol, a substance found in red grapes and red wine, may have the potential to protect against hearing and cognitive decline, according to a published laboratory study from Henry Ford Hospital in Detroit.

21 Feb 2013

BCHE gene variant predicts extent of plaque deposits in Alzheimer's

A study combining genetic data with brain imaging, designed to identify genes associated with the amyloid plaque deposits found in Alzheimer's disease patients, has not only identified the APOE gene -- long associated with development of Alzheimer's -- but has uncovered an association with a second gene, called BCHE.

21 Feb 2013

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Shortage of TDP-43 protein causes muscle wasting and stunted nerve cells

Oxford researcher wins 2013 John Dystel Prize from AAN, National Multiple Sclerosis Society

Researchers identify novel signaling pathway responsible for neuroprotective activity of parkin

AAN to award 2013 Michael S. Pessin Stroke Leadership Prize to Amytis Towfighi

Remembering proper eating habits can improve physical health and reduce depression

Otsuka receives FDA approval for ABILIFY MAINTENA to treat schizophrenia

Researchers develop new genetically altered mice that model earliest stages of Alzheimer's

Amyloid plaques take about 15 years to build up and then plateau: Study

Jones & Bartlett Learning publishes 'Introduction to Neurogenic Communication Disorders'

Proper eating habits in dementia patients can improve their physical health and lessen symptoms of depression

Researchers to discuss health issues at Society of Toxicology's Annual Meeting and ToxExpo

MID1 complex binds with messenger RNA and controls synthesis of defective Huntingtin

Researchers discover novel way to image the entire brain's glymphatic pathway

WUSTL to develop 3-D computer models of brain biomechanics to better understand TBI

Researchers identify several genes associated with human neurological disorders

Major doctor group coalition expands list of tests, treatments that should be done only rarely

Targeting CSF1R with selective inhibitors could help Alzheimer's

Researchers use familial and sporadic patient-derived iPSCs to model Alzheimer's disease

Resveratrol may protect against hearing and cognitive decline

BCHE gene variant predicts extent of plaque deposits in Alzheimer's

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

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