Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Dietary antioxidants may not protect against stroke and dementia

Contrary to other research, a new study found that the total level of antioxidants in people's diets is not related to their risk of developing stroke or dementia.

21 Feb 2013

NINDS to award TSRI scientist with $3.5M Jacob K. Javits Neuroscience Investigator Award

Ron Davis, PhD, chair of the Neuroscience Department on the Florida campus of The Scripps Research Institute, has been selected to receive a prestigious $3.5 million Jacob K. Javits Neuroscience Investigator Award for his work on the complex biology of memory formation and the disorders that disrupt it.

21 Feb 2013

Methylene blue inactivates molecular residues that promote bonding of tau proteins

The study published in "Angewandte Chemie" might help to work out strategies for developing potential drugs. As the team of scientist including Markus Zweckstetter and Eckhard Mandelkow report, methylene blue inactivates molecular residues that promote the bonding of tau proteins.

21 Feb 2013

Insight into how NMDA receptors function

In a pair of new papers, researchers at the University of California, San Diego School of Medicine and the Royal Netherlands Academy of Arts and Sciences upend a long-held view about the basic functioning of a key receptor molecule involved in signaling between neurons, and describe how a compound linked to Alzheimer's disease impacts that receptor and weakens synaptic connections between brain cells.

20 Feb 2013

New system can help spot sleep disturbance in people with early dementia

A new sleep pattern monitoring system has been developed by UK researchers to help spot sleep disturbance in people diagnosed with early dementia. The system, known as PAViS, could be used remotely by healthcare workers to view sleep profiles and analyse sleep patterns based on sensory data gathered at the patient's home.

19 Feb 2013

Brain damage can persist for decades after original head trauma

As the National Football League braces for lawsuits by 4000 former players alleging the league failed to protect them from the long-term consequences of concussions, game-changing research by a leading Canadian researcher shows damage to the brain can persist for decades after the original head trauma.

17 Feb 2013

Brain health just as important as physical health

We all know the importance of keeping healthy and are familiar with the refrains of 'exercise more', 'eat better' and 'get regular physicals'. But what about our mental health? Professor Barbara Sahakian, best known for her expertise on cognitive enhancers, challenges society (and government) to prioritise mental health in the same way as we do physical health.

17 Feb 2013

The Y rolls out new health program targeting diabetes

YMCAs will advance the program nationally with support from insurers and employers. Also in the news, researchers express concern about the increasing costs likely to accompany soaring Alzheimer's disease rates.

16 Feb 2013

TSG might be novel compound for treatment of Alzheimer's and dementia with Lewy body

Administration of the active compound tetrahydroxystilbene glucoside (TSG) derived from the Chinese herbal medicine Polygonum multiflorum Thunb, reversed both overexpression of α-synuclein, a small protein found in the brain, and its accumulation using a mouse model of Alzheimer's disease.

16 Feb 2013

Tau release from healthy neurons can be regulated by neuronal activity

Researchers from King's College London have discovered that neuronal activity can stimulate tau release from healthy neurons in the absence of cell death.

16 Feb 2013

First Edition: February 15, 2013

Today's headlines include news about how the health law's insurance exchanges are taking shape.

15 Feb 2013

Protein-restricted diet supplemented with IGF-I may protect from Alzheimer's

Mice with many of the pathologies of Alzheimer's Disease showed fewer signs of the disease when given a protein-restricted diet supplemented with specific amino acids every other week for four months.

15 Feb 2013

Targacept reports net loss of $15.9 million for fourth quarter 2012

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics, today reported its financial results for the fourth quarter and year ended December 31, 2012.

14 Feb 2013

Study demonstrates how CN2097 works to restore neural functions impaired by Angelman syndrome

In a new study in mice, a scientific collaboration centered at Brown University lays out in unprecedented detail a neurological signaling breakdown in Angelman syndrome, a disorder that affects thousands of children each year, characterized by developmental delay, seizures, and other problems.

14 Feb 2013

Antibody therapeutics targeting GPCRs to be developed by alliance between MorphoSys and Heptares

MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX) and UK-based Heptares Therapeutics, the leading GPCR drug discovery and development company, have signed an agreement to discover novel antibody therapeutics targeting G protein-coupled receptors (GPCRs), which are membrane proteins involved in a broad range of biological processes and diseases.

13 Feb 2013

Study finds abnormal production of C9RANT in patients with ALS, frontotemporal dementia

Researchers at Mayo Clinic have discovered an abnormal protein that accumulates in the brains of many patients affected with two common neurodegenerative disorders — amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig's disease, and frontotemporal dementia.

13 Feb 2013

Boston College biologist receives $2.7M NIH grant to continue HIV and AIDS research

Boston College biologist Ken Williams, whose research focuses on the role of immunological cells in a range of illnesses that strike people living with HIV and AIDS, has been awarded a five-year, $2.7 million grant from the NIH's National Institute of Neurological Disorders and Stroke.

12 Feb 2013

Brookdale fourth quarter total revenue increases 4.1% to $699.7 million

Brookdale Senior Living Inc. today reported financial and operating results for the fourth quarter and full year 2012.

11 Feb 2013

Scientists identify enigmatic aggregates linked to neurodegenerative diseases

The proteins that have now been identified shouldn't actually exist. Nevertheless, they build the core of cellular aggregates whose identity has been enigmatic until now. These aggregates are typically associated with hereditary neurodegenerative diseases including variants of frontotemporal dementia (FTD), also known as frontotemporal lobar degeneration (FTLD), and amyotrophic lateral sclerosis (ALS). They are likely to be damaging and might be a target for therapy.

11 Feb 2013

Four-month instructional dance program can improve health of Latino seniors

Vigorous activity can improve the physical and mental health of older adults, but for many, particularly Latinos, exercise is not a regular part of their lives, according to a University of Illinois at Chicago researcher.

11 Feb 2013

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Dietary antioxidants may not protect against stroke and dementia

NINDS to award TSRI scientist with $3.5M Jacob K. Javits Neuroscience Investigator Award

Methylene blue inactivates molecular residues that promote bonding of tau proteins

Insight into how NMDA receptors function

New system can help spot sleep disturbance in people with early dementia

Brain damage can persist for decades after original head trauma

Brain health just as important as physical health

The Y rolls out new health program targeting diabetes

TSG might be novel compound for treatment of Alzheimer's and dementia with Lewy body

Tau release from healthy neurons can be regulated by neuronal activity

First Edition: February 15, 2013

Protein-restricted diet supplemented with IGF-I may protect from Alzheimer's

Targacept reports net loss of $15.9 million for fourth quarter 2012

Study demonstrates how CN2097 works to restore neural functions impaired by Angelman syndrome

Antibody therapeutics targeting GPCRs to be developed by alliance between MorphoSys and Heptares

Study finds abnormal production of C9RANT in patients with ALS, frontotemporal dementia

Boston College biologist receives $2.7M NIH grant to continue HIV and AIDS research

Brookdale fourth quarter total revenue increases 4.1% to $699.7 million

Scientists identify enigmatic aggregates linked to neurodegenerative diseases

Four-month instructional dance program can improve health of Latino seniors

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

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