Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Radisphere announces availability of next 'Quality Update' piece

Radisphere, the only radiology provider offering proven accessibility and accountability to community hospitals, today announced availability of its next "Quality Update" piece as part of its "The Final Read on Quality" initiative.

17 Mar 2012

ApoE4 gene could cause early loss of synapses in Alzheimer's disease

Today, researchers at the Blanchette Rockefeller Neurosciences Institute (BRNI) at West Virginia University in Morgantown, West Virginia reported a significant advance in understanding how different forms of the ApoE gene raise the risk for Alzheimer's disease.

17 Mar 2012

SK Biopharmaceuticals initiates YKP10811 phase 2 trial in chronic constipation

SK Biopharmaceuticals, a South Korean pharmaceutical company, announced today that the first patient was dosed in a phase 2 clinical trial in the US for patients suffering with chronic constipation using their new chemical entity YKP10811.

17 Mar 2012

Older women with mild retinopathy more likely to have cognitive decline and related vascular changes

Women 65 or older who have even mild retinopathy, a disease of blood vessels in the retina, are more likely to have cognitive decline and related vascular changes in the brain, according to a multi-institutional study led by scientists at the University of California, San Francisco (UCSF).

16 Mar 2012

Eight European research institutes partner to provide training on systemic neuroscience

Eight European research institutes, including Johannes Gutenberg University Mainz (JGU), and three commercial partners have joined forces in an EU project to provide young academics with an outstanding research environment in the field of systemic neuroscience.

16 Mar 2012

Viewpoints: Health costs crushing Detroit; Military care still faces funding issues; Romneycare scores

Legacy costs are bankrupting Detroit just as they crushed its automakers. Firefighters can retire at 55 and earn 70% of their highest salary plus a 2.25% annual cost-of-living inflator in perpetuity. The result? Employee benefits alone now make up about half of the city's general fund. Health costs have grown by more than 60% since 2008 while the city's pension bill has quadrupled to $200 million.

16 Mar 2012

Combination therapy may improve life span and motor function of infants with Batten disease

Infants with Batten disease, a rare but fatal neurological disorder, appear healthy at birth. But within a few short years, the illness takes a heavy toll, leaving children blind, speechless and paralyzed. Most die by age 5.

16 Mar 2012

Women with retinopathy more likely to have cognitive problems

People with mild vascular disease that causes damage to the retina in the eye are more likely to have problems with thinking and memory skills because they may also have vascular disease in the brain, according to a study published in the March 14, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

15 Mar 2012

New UCLA Alzheimer's and Dementia Care program for patients, caregivers

Alzheimer's disease affects an estimated 5.4 million people in the U.S., some 480,000 of them in California. Nearly half of all people 85 and older will be stricken with the disease. The overall burden of dementia is still higher, with Alzheimer's accounting for only 60 to 80 percent of dementia cases.

15 Mar 2012

New RAGE inhibitor shows promise against Alzheimer's

Researchers have taken another crack at a promising approach to stopping Alzheimer's disease that encountered a major hurdle last year. In research published this week in the Journal of Clinical Investigation, scientists have developed a compound that targets a molecular actor known as RAGE, which plays a central role in mucking up the brain tissue of people with the disease.

15 Mar 2012

People with RBD more likely to develop Parkinson's, MCI

People with symptoms suggesting rapid eye movement sleep behavior disorder, or RBD, have twice the risk of developing mild cognitive impairment (MCI) or Parkinson's disease within four years of diagnosis with the sleep problem, compared with people without the disorder, a Mayo Clinic study has found.

15 Mar 2012

State roundup: Caregivers face 'burnout' threat as need grows, Kansas nursing home staff inadequate?

Long term care advocates say they're concerned about caregiver burnout. And they say Wisconsin may be overestimating projected savings from uncompensated care that relatives provide. State health officials need to find nearly $80 million in savings from a popular program that keeps the elderly and disabled out of nursing homes. The administration wants to know what assistance friends and family are giving so that care isn't replaced by Medicaid services.

15 Mar 2012

Potential new way to treat rare inherited metabolic disorders

A University of Michigan cell biologist and his colleagues have identified a potential drug that speeds up trash removal from the cell's recycling center, the lysosome.

14 Mar 2012

Microbubbles and focused ultrasound help drugs enter the brain

One of the trickiest parts of treating brain conditions is the blood brain barrier, a blockade of cells that prevent both harmful toxins and helpful pharmaceuticals from getting to the body's control center. But, a technique published in JoVE, uses an MRI machine to guide the use of microbubbles and focused ultrasound to help drugs enter the brain, which may open new treatment avenues for devastating conditions like Alzheimer's and brain cancers.

14 Mar 2012

Scientists gain insight into why lithium salts are effective at treating bipolar disorder

Scientists have gained insight into why lithium salts are effective at treating bipolar disorder in what could lead to more targeted therapies with fewer side-effects.

14 Mar 2012

Yoga can improve cognitive functioning and reduce depression in dementia caregivers

For every individual who's a victim of Alzheimer's - some 5.4 million persons in the United States alone - there's a related victim: the caregiver. Spouse, son, daughter, other relative or friend, the loneliness, exhaustion, fear and most of all stress and depression takes a toll.

14 Mar 2012

Biomedical research advances through new Australian Institute

The Institute of Biomedical Engineering and Technology (BMET) will be officially opened this evening at the University of Sydney, and will significantly advance this highly multidisciplinary research for life sciences and medicine.

14 Mar 2012

JAK-STAT inhibitors reverse MS-like disease in mice

A new class of drugs completing clinical trials soon for rheumatoid arthritis should be examined as a treatment for multiple sclerosis, according to the authors of a University of Alabama at Birmingham study published today in the Proceedings of the National Academy of Sciences.

13 Mar 2012

Human diseases with Drosophila counterparts discussed at annual conference

More than two-thirds of human genes have counterparts in the well-studied fruit fly, Drosophila melanogaster, so although it may seem that humans don't have much in common with flies, the correspondence of our genetic instructions is astonishing. In fact, there are hundreds of inherited diseases in humans that have Drosophila counterparts.

12 Mar 2012

Allon advances into second phase of work in preclinical PD model

Allon Therapeutics Inc. announced today the completion of its first phase of work in a preclinical Parkinson's disease model and advancement into the second phase of work. Both phases are funded by The Michael J. Fox Foundation for Parkinson's Research and carried out by Prof. Marie-Francoise Chesselet's lab at the University of California Los Angeles.

12 Mar 2012