Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Alzheimer's disease drugs may act like a bad electrician

Alzheimer's disease drugs now being tested in clinical trials may have potentially adverse side effects, according to new Northwestern Medicine research. A study with mice suggests the drugs could act like a bad electrician, causing neurons to be miswired and interfering with their ability to send messages to the brain.

29 Feb 2012

AAN, ALS Association announce creation of Richard Olney Clinician Scientist Development Award

The American Academy of Neurology Foundation and The ALS Association are announcing the creation of the Richard Olney Clinician Scientist Development Award in ALS, named after Richard K. Olney, MD, a leading neurologist and pioneer in clinical ALS research who died late last month of ALS, also known as amyotrophic lateral sclerosis, or Lou Gehrig's disease.

29 Feb 2012

Targeting O-GlcNAcase enzyme with inhibitors might treat Alzheimer's

Slowing or preventing the development of Alzheimer's disease, a fatal brain condition expected to hit one in 85 people globally by 2050, may be as simple as ensuring a brain protein's sugar levels are maintained.

29 Feb 2012

Mantra-based meditation shows promise against age-associated cognitive impairment

Researchers at Thomas Jefferson University Hospital determined that mantra-based meditation can have a positive impact on emotional responses to stress, fatigue and anxiety in adults with memory impairment and memory loss.

29 Feb 2012

DKR Fund for Alzheimer's research launches today

The Darrell K Royal Fund for Alzheimer's Research was launched today at an Interim Joint Committee hearing on Alzheimer's Disease (AD) in the Texas Senate Chamber. The DKR Fund is named after legendary Texas football coach Darrell Royal and was created to facilitate research and care for Texans to attempt to cure AD in our lifetimes.

29 Feb 2012

Single dose of Ritalin may raise awareness of mistakes: Study

The study, by Dr Rob Hester from the Department of Psychological Sciences and colleagues at the Queensland Brain Institute, investigated how the brain monitors ongoing behavior for performance errors – specifically failures of impulse control. This study found that a single dose of methylphenidate (Ritalin) results in significantly greater activity in the brain’s error monitoring network and improved volunteers’ awareness of their mistakes.

28 Feb 2012

Low levels of omega-3 in blood ‘ups’ risk of dementia and brain aging: Study

Researchers looked at 1,575 adults who averaged 67 years old and had no signs of dementia and had not had a stroke. They were given MRI brain scans and a battery of tests to measure memory and thinking abilities; they also had blood drawn to check the level of docosahexaenoic acid (DHA) or omega-3 fatty acids in their red blood cells. Those with the lowest levels of omega-3s showed signs of accelerated aging. They had lower brain volume, indicating shrinkage comparable to two additional years of aging. Compared with those with the highest blood levels of omega-3s, they scored lower on cognitive tests measuring such things as memory, problem solving, abstract thinking and multi-tasking.

28 Feb 2012

AF strong predictor of cognitive and functional decline in older people at risk of heart disease

An irregular heartbeat - atrial fibrillation - is a strong predictor of cognitive decline and the loss of independence in daily activities in older people at risk of cardiovascular disease, according to a study in CMAJ.

28 Feb 2012

Diets low in omega-3 fatty acids linked with memory problems

A diet lacking in omega-3 fatty acids, nutrients commonly found in fish, may cause your brain to age faster and lose some of its memory and thinking abilities, according to a study published in the February 28, 2012, print issue of Neurology, the medical journal of the American Academy of Neurology.

28 Feb 2012

Hearing loss may increase risk of falls

Hearing loss has been linked with a variety of medical, social and cognitive ills, including dementia. However, a new study led by a Johns Hopkins researcher suggests that hearing loss may also be a risk factor for another huge public health problem: falls.

27 Feb 2012

State roundup: State tobacco funds scrutinized; More allegations against Calif.'s Prime Healthcare; Ore. CCOs get green light

A U.S. Surgeon General's report due to be released March 8 will come down hard on states that have cut anti-smoking funds in tough fiscal times, said Terry Pechacek, who oversees the report as director for Science in the Office on Smoking and Health at the Centers for Disease Control and Prevention. The report can't result in sanctions, but it has proven to move public opinion in the past to force changes by tobacco companies in how they sell cigarettes, how states fund efforts and how the federal government regulates the trade.

27 Feb 2012

Ritalin improves awareness of performance errors

People who take Ritalin are far more aware of their mistakes, a University of Melbourne study has found.

27 Feb 2012

ATI commences European trial of neurostimulation system for migraine

Autonomic Technologies, Inc. (ATI), the developer of a novel miniaturized implantable stimulator for severe headaches, today announced initiation of a study in Europe to evaluate the safety and efficacy of the company's investigational neurostimulation system for the treatment of high frequency, high disability migraine.

27 Feb 2012

H2S transforms dental pulp stem cells into liver cells

Japanese scientists have found that the odorous compound responsible for halitosis - otherwise known as bad breath - is ideal for harvesting stem cells taken from human dental pulp.

27 Feb 2012

Helmholtz Association grant for research on diseases caused by protein misfolding

Professor Erich Wanker of the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch and of the Excellence Cluster Neurocure is to receive EUR 675 000 in funding from the Helmholtz Association over the next two years. The grant shall be used to accelerate the search for active agents to treat diseases that are caused by protein misfolding. These include Alzheimer's and Parkinson's.

24 Feb 2012

Dopamine therapy can boost creativity in patients with Parkinson's

Some Parkinson's Disease patients can suddenly become creative when they take dopamine therapy, producing pictures, sculptures, novels and poetry. But their new-found interests can become so overwhelming that they ignore other aspects of their everyday life, such as daily chores and social activities, according to research published in the March issue of the European Journal of Neurology.

24 Feb 2012

Draft national plan to fight Alzheimer's released

A framework for the plan was unveiled in January. This more fleshed-out version builds on that outline, makes treatment a top priority and focuses on the burden the disease places on families and caregivers.

24 Feb 2012

UM scientists discover high concentrations of BMAA in shark fins

Sharks are among the most threatened of marine species worldwide due to unsustainable overfishing. Sharks are primarily killed for their fins alone, to fuel the growing demand for shark fin soup, which is an Asia delicacy. A new study by University of Miami (UM) scientists in the journal Marine Drugs has discovered high concentrations of BMAA in shark fins, a neurotoxin linked to neurodegenerative diseases in humans including Alzheimer's and Lou Gehrig Disease.

24 Feb 2012

UBC develops algorithm to predict how and when proteins misfold

Several neurodegenerative diseases - including Alzheimer's and ALS (Lou Gehrig's disease) - are caused when the body's own proteins fold incorrectly, recruit and convert healthy proteins to the misfolded form, and aggregate in large clumps that gum up the works of the nervous system. "For Star Trek fans, this is like the Borg, a fictional race of cyborgs that abduct and assimilate humans and other species," says Steven Plotkin, a biophysicist at the University of British Columbia in Vancouver who studies the process of protein misfolding.

24 Feb 2012