Bipolar Disorder News and Research

Latest Bipolar Disorder News and Research

Variation in Ankyrin 3 gene shows strong association with bipolar disorder

The largest genetic analysis of its kind to date for bipolar disorder has implicated machinery involved in the balance of sodium and calcium in brain cells. Researchers supported in part by the National Institute of Mental Health, part of the National Institutes of Health, found an association between the disorder and variation in two genes that make components of channels that manage the flow of the elements into and out of cells, including neurons.

17 Aug 2008

FDA approves first generic divalproex sodium for the treatment of seizures, bipolar disorder and migraine headaches

The U.S. Food and Drug Administration today approved the first generic versions of Depakote delayed-release tablets (divalproex sodium). Depakote is approved by the FDA for the treatment of seizures, bipolar disorder and migraine headaches.

29 Jul 2008

Using genetics to improve traditional psychiatric diagnoses

Psychiatry has begun the laborious effort of preparing the DSM-V, the new iteration of its diagnostic manual. In so doing, it once again wrestles with the task set by Carl Linnaeus, to "cleave nature at its joints." However, these "joints," the boundaries between psychiatric disorders, such as that between bipolar disorder and schizophrenia, are far from clear. Prior versions of DSM followed the path outlined by Emil Kraeplin in separating these disorders into distinct categories. Yet, we now know that symptoms of bipolar disorder may be seen in patients with schizophrenia and the reverse is true, as well.

17 Jul 2008

Shared gene expression alterations in schizophrenia and bipolar disorder

Both schizophrenia and bipolar disorder can be disabling conditions, and both present clinically with significant mood and psychotic symptoms. These two illnesses also share genetic variants that might be involved in the predisposition to both disorders.

17 Jul 2008

An analysis of food's affect on the brain

In addition to helping protect us from heart disease and cancer, a balanced diet and regular exercise can also protect the brain and ward off mental disorders.

9 Jul 2008

Genetic change in dopamine transporter supports a role for dopamine signaling in ADHD

A genetic change in the dopamine transporter - one of the brain's dopamine-handling proteins - makes it behave as if amphetamine is present and "run backward," Vanderbilt University Medical Center investigators report this week in The Journal of Neuroscience.

9 Jul 2008

Black box warning for epilepsy drugs

The U.S. Food and Drug Administration (FDA) is calling for the strongest type of warning to be placed on drugs which are used to treat epilepsy.

8 Jul 2008

North Carolina mental health parity law comes into effect

North Carolina health care insurers must provide the same amount of coverage for certain mental conditions as they do for physical ailments under a state law that took effect on Tuesday, the Winston-Salem Journal reports.

3 Jul 2008

FDA approves generic Risperidone for the treatment of schizophrenia, bipolar disorder

The U.S. Food and Drug Administration today approved the first generic versions of Risperdal (risperidone) tablets. Risperdal is an antipsychotic drug used for the treatment of schizophrenia, bipolar disorder, and other psychiatric conditions.

1 Jul 2008

Canada's mental health crisis

No one is safe from mental illness; it strikes without regard for age, gender, or social status. And even though one in four Canadians suffer from a mental illness, it remains a stigma, shrouded in misconceptions.

24 Jun 2008

Bipolar disorder in adolescents is a huge risk factor for smoking and substance abuse

A study from the Massachusetts General Hospital (MGH) supports previous reports that adolescents with bipolar disorder are at increased risk for smoking and substance abuse.

2 Jun 2008

Antipsychotic drugs dangerous for the elderly

A Canadian study has found that prescribing antipsychotic drugs for elderly people may be dangerous.

27 May 2008

Mentally ill often trapped in poverty/debt cycle

A study by a mental health charity has found that many people with mental health problems often go without food because of financial problems.

12 May 2008

Study identifies problems with diagnosis of bipolar disorder

A new study by Rhode Island Hospital and Brown University researchers reports that fewer than half the patients previously diagnosed with bipolar disorder received a diagnosis of bipolar disorder based on a comprehensive, psychiatric diagnostic interview--the Structured Clinical Interview for DSM-IV (SCID).

6 May 2008

Omega-3 fatty acids for bipolar disorder

Despite intriguing findings that omega-3 fatty acid supplements could alleviate depression symptoms, there is still not enough evidence to say whether omega-3s are useful treatments for people with bipolar disorder, according to a review of recent studies.

22 Apr 2008

Unbiased, comprehensive analysis of drug research from new web site

Physicians and consumers who want fair and balanced information about the most appropriate uses for prescription medications can now find it using a Web-based resource that provides easily accessible, science-based research about drug uses free from pharmaceutical industry influence.

17 Apr 2008

Aripiprazole has potential for treating alcohol dependence

Aripiprazole is currently approved to treat bipolar disorder as well as schizophrenia. A new study has found that it significantly and dose-dependently increases the sedative effects of alcohol and, to a lesser degree, decreases the euphoric effects of alcohol. Future research will need to examine the beneficial versus the side effects of aripiprazole for treatment of alcohol dependence.

4 Apr 2008