Cancer News and Research

Latest Cancer News and Research

AI revolutionizes cancer research with advanced tools

Significant advancements in understanding the molecular and cellular mechanisms of tumor progression have been made, yet challenges remain.

13 Dec 2024

Strategies to overcome social challenges in cancer prevention

Researchers at University of California San Diego and collaborating institutions have shed light on the ways that social risks, such as housing or food insecurity, pose barriers to routine cancer screenings.

13 Dec 2024

Lifestyle medicine education empowers clinicians

Clinicians who completed an American College of Lifestyle Medicine (ACLM) course introducing the foundations of lifestyle medicine and food as medicine reported significant improvements in their knowledge and confidence, as well as increases in how often they practice lifestyle medicine with patients, a research study found.

13 Dec 2024

Unraveling the mystery of drug-induced liver injury

DILI is broadly categorized into intrinsic and idiosyncratic types. Intrinsic hepatotoxins, such as APAP, cause dose-dependent injury, while idiosyncratic DILI involves complex immune and metabolic interactions that remain poorly understood.

13 Dec 2024

DTI detects precancerous lesions in the pancreas

Precursor lesions of pancreatic cancer are very difficult to characterize with magnetic resonance imaging (MRI). But now, in a new study, researchers led by Noam Shemesh and Carlos Bilreiro – respectively head of the Preclinical MRI lab at Champalimaud Research and a doctor at the Champalimaud Clinical Centre's Radiology Department – have shown, for the first time, that a particular form of MRI, called Diffusion Tensor Imaging (DTI), is capable of robustly detecting pre-malignant lesions in the pancreas.

13 Dec 2024

Disrupting the circadian rhythm of glioblastoma slows tumor growth, study says

Virtually every cell in the human body has an internal clock. These clocks take their cues from a central clock in the brain. In a normal, biological process called synchrony, the central clock coordinates daily rhythms around the body, so that every cell and tissue recognizes the same external time of day.

13 Dec 2024

A novel approach to prevent severe liver disease in diabetes

New research from Karolinska Institutet in Sweden highlights the possibility of screening people with type 2 diabetes for liver damage at the same time as they undergo screening for eye disease. The study is published in Lancet Gastroenterology and Hepatology.

13 Dec 2024

Improving head and neck reconstruction with a modified pedicled flap

Osaka Metropolitan University researchers have developed a promising technique for head and neck reconstruction that shifts the placement of transferred tissue with blood vessels attached, offering a safer, faster option for patients with complex tissue defects, especially those at high risk.

13 Dec 2024

Harnessing the power of AI to optimize breast cancer management

The future of breast cancer screening and risk-reducing strategies is being shaped by artificial intelligence (AI), according to a review article published by Cell Press on December 12 in the journal Trends in Cancer.

13 Dec 2024

A genetic variant modulates interferon signaling and disease risk

For years, scientists have looked to a critical piece of immune system machinery - known as the interferon pathway - for answers. There, when our cells sense an infection, they release a protein known as interferon, which warns other cells to fight the virus.

13 Dec 2024

Deep learning transforms PDAC diagnosis and treatment

Researchers have successfully developed a deep learning model that classifies pancreatic ductal adenocarcinoma (PDAC), the most common form of pancreatic cancer, into molecular subtypes using histopathology images.

13 Dec 2024

Metastatic breast cancer rates surge across U.S. women, exposing disparities and pandemic impacts

Metastatic breast cancer diagnoses are rising in U.S. women, especially in younger age groups and racial minorities, as revealed by SEER data from 2004–2021. The study highlights disparities and COVID-19's impact, urging systemic changes to improve early detection and healthcare equity.

12 Dec 2024

Lipid imbalances hold the key to chronic inflammation in colon cancer

Scientists uncover how disrupted lipid metabolism fuels chronic inflammation in colorectal cancer, offering insights into new therapeutic strategies targeting pro-inflammatory and pro-resolving lipid imbalances.

12 Dec 2024

Insilico Medicine gets first clinical milestone payment of $10 million for XL309

Insilico Medicine ('Insilico'), a clinical-stage generative artificial intelligence (AI)-driven drug discovery and development company, today announced that it has received the first clinical milestone payment of $10 million for XL309 (previously known as ISM3091) from Exelixis.

12 Dec 2024

Chest wall irradiation does not impact 10-year survival in intermediate-risk breast cancer

Patients with intermediate-risk breast cancer had similar rates of 10-year overall survival whether or not they underwent chest wall irradiation (CWI) after mastectomy, according to results from the BIG 2-04 MRC SUPREMO clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

12 Dec 2024

Active monitoring for low-risk DCIS results in similar quality of life as standard treatment

Patients with low-risk ductal carcinoma in situ (DCIS) who underwent active monitoring reported comparable physical, emotional, and psychological outcomes to patients who received upfront treatment, according to results from the COMET clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

12 Dec 2024

COMET trial shows active monitoring is noninferior to standard treatment for low-risk DCIS

Among patients with hormone receptor (HR)-positive, HER2-negative, low-risk ductal carcinoma in situ (DCIS), those who underwent active monitoring had similar two-year invasive ipsilateral breast cancer recurrence rates as those who underwent guideline-concordant treatment, according to results from the COMET clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

12 Dec 2024

PATINA trial demonstrates benefit of palbociclib in HR+ HER2+ metastatic breast cancer

Alliance Foundation Trials, LLC (AFT) and Pfizer Inc. today announced results from the phase III PATINA trial demonstrating that the addition of palbociclib (IBRANCE) to current standard-of-care first-line maintenance therapy (following induction chemotherapy) resulted in statistically significant and clinically meaningful improvement in progression-free survival (PFS) by investigator assessment in patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-positive (HER2+) metastatic breast cancer (MBC).

12 Dec 2024

Tamoxifen lowers breast cancer recurrence in good-risk DCIS patients

For patients with "good-risk" ductal carcinoma in situ (DCIS) who underwent breast- conserving surgery and did not receive radiotherapy, tamoxifen significantly decreased the risk of recurrence in the same breast, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

12 Dec 2024

Study links early-life tonsil removal to long-term risk of stress-related disorders

Researchers explore the potential association between tonsillectomy and adenoid removal in the risk of developing stress-related disorders in later life.

12 Dec 2024