Cancer News and Research

Latest Cancer News and Research

Promising combination therapy could improve liver cancer outcomes

Dan G. Duda, DMD, PhD, of the Edwin L. Steele Laboratories for Tumor Biology and Department of Radiation Oncology at Massachusetts General Hospital, is the corresponding author of a paper published in Cancer Immunology Research, "Combination CXCR4 and PD1 Blockade Enhances Intratumoral Dendritic Cell Activation and Immune Responses Against Hepatocellular Carcinoma."

14 Dec 2024

Genetic insights into reproductive health and longevity

Led by researchers from the University of Oxford's Leverhulme Centre for Demographic Science and the University of Iceland, the review explores how genetic variations can explain differences in reproductive health and longevity.

14 Dec 2024

Gene variant in Andean populations could help predict blood cancer treatment outcomes

Two researchers from Huntsman Cancer Institute at the University of Utah (the U) have discovered a gene variant found in high-altitude Andean populations that they believe could be a new biomarker for predicting the severity of diseases and treatment responses for certain types of blood cancer.

14 Dec 2024

ZEST trial fails to meet enrollment goals for ctDNA testing in breast cancer

The ZEST clinical trial, designed to evaluate niraparib (Zejula) for the prevention of breast cancer recurrence in patients with circulating tumor DNA (ctDNA), failed to accrue enough patients positive for ctDNA, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

14 Dec 2024

Study unveils key mechanism behind prostate cancer's uncontrolled growth

Prostate cancer hijacks the normal prostate's growth regulation program to release the brakes and grow freely, according to Weill Cornell Medicine researchers.

14 Dec 2024

Machine learning model predicts CDK4/6 inhibitor effectiveness in metastatic breast cancer

A machine learning (ML) model incorporating both clinical and genomic factors outperformed models based solely on either clinical or genomic data in predicting which patients with hormone receptor (HR)-positive, HER2-negative metastatic breast cancer would have better outcomes from adding CDK4/6 inhibitors to endocrine therapy as first-line treatment, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

14 Dec 2024

Targeted gene therapy shuts down cancer cells' energy centers

Researchers are shining a light on cancer cells' energy centers – literally – to damage these power sources and trigger widespread cancer cell death.

14 Dec 2024

Adjuvant anthracycline- plus taxane-based chemotherapy regimen improves survival in high-risk breast cancer patients

Patients with early-stage, node-negative, hormone receptor (HR)-positive, HER2- negative breast cancer who have a high risk of recurrence based on the OncotypeDX genomic test had better outcomes when treated with adjuvant anthracycline- plus taxane-based chemotherapy regimens compared with those receiving adjuvant taxane-based chemotherapy regimens alone, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

14 Dec 2024

CNIC team develops a comprehensive set of genetic tools and mouse lines

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has developed a comprehensive set of innovative genetic tools and mouse lines, called iFlpMosaics, designed to enhance the study of gene function and its implications in health and disease.

14 Dec 2024

Exploring the cytotoxic potential of neocryptolepine derivatives against cancer

Announcing a new publication for Acta Materia Medica journal. Cancer has been a severe public health and social problem, a leading disease that has diminished the quality of life, and a barrier to improving life expectancy.

13 Dec 2024

Zeqi exhibits multifunctional therapeutic potential in modern medicine

Announcing a new publication for Acta Materia Medica journal. Zeqi (Euphorbia helioscopia L.), is a widely distributed plant of the Euphorbiaceae family.

13 Dec 2024

New technique offers safer option for head and neck reconstruction

Sometimes, moving just a few inches can go a long way. Osaka Metropolitan University researchers have developed a promising technique for head and neck reconstruction that shifts the placement of transferred tissue with blood vessels attached, offering a safer, faster option for patients with complex tissue defects, especially those at high risk.

13 Dec 2024

New HPV self-test approach could enhance cervical cancer screening

Analyses of self-tests for human papillomavirus (HPV) can be used to divide HPV-positive women into three risk groups, according to a new study from Karolinska Institutet and Queen Mary University of London published in PLOS Medicine.

13 Dec 2024

Cardio-oncology experts highlight importance of heart health in cancer care

The devastating news of a cancer diagnosis understandably makes doctors and patients focus on the cancer itself.

13 Dec 2024

Study links intermittent fasting to slower hair growth

Intermittent fasting has proven benefits for metabolic health, but a new study shows that it could slow hair growth - at least in mice.

13 Dec 2024

Study highlights the impact of Reiki on pain, fatigue, and anxiety in cancer outpatients

A recent study conducted at University Hospitals Connor Whole Health has evaluated a Reiki program designed for outpatients with cancer and receiving infusion treatments at two University Hospitals infusion centers.

13 Dec 2024

Multi-omic profiling sheds light on chemo-immunotherapy resistance in lung cancer

The study characterizes the lung cancer tumor microenvironment, linking cellular compositions to immunotherapy resistance and potential therapeutic strategies.

13 Dec 2024

New protein platform enhances cancer immunotherapy

Researchers from Children's Hospital of Philadelphia (CHOP) and Stanford University have revealed the molecular structure of TRACeR-I, a protein platform for reprogramming immune responses. A better understanding of its structure may help optimize designs for the platform, which can be used to develop cancer treatments by either directly modifying immune cells or by creating proteins that help immune cells locate cancer cells. The findings were published today by the journal Nature Biotechnology.

13 Dec 2024

AI revolutionizes cancer research with advanced tools

Significant advancements in understanding the molecular and cellular mechanisms of tumor progression have been made, yet challenges remain.

13 Dec 2024

Strategies to overcome social challenges in cancer prevention

Researchers at University of California San Diego and collaborating institutions have shed light on the ways that social risks, such as housing or food insecurity, pose barriers to routine cancer screenings.

13 Dec 2024