Cancer News and Research

Latest Cancer News and Research

Combining anti-tumor antibodies with standard-of-care improves therapeutic outcomes in cancer

The cover for issue 2 of Oncotarget features Figure 4, "Combination therapy TA99/ICB reduced the lung tumor burden in the B16 model of metastases," published in "Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma" by Pérez-Lorenzo, et al. which reported that here, the authors showed that removing immune suppression and enhancing stimulatory signals increased the anti-tumor activity of unmodified TA99 antibodies with a significant reduction of growth of solid tumors and lung metastases in mouse models of melanoma.

25 Jan 2021

Reduced expression of TBX15 in tumor tissue represents a prognostic biomarker for HCC patients

The cover for issue 52 of Oncotarget features Figure 1, "Volcano plots of DNA methylation in tumor tissues compared with nontumor tissue," published in "Reduction of T-Box 15 gene expression in tumor tissue is a prognostic biomarker for patients with hepatocellular carcinoma" by Morine, et al. which reported that the authors conducted a genome-wide analysis of DNA methylation of the tumor and non-tumor tissue of 15 patients with Hepatocellular carcinoma (HCC), and revealed TBX15 was the most hypermethylated gene of the tumor.

25 Jan 2021

Second-generation double antibody protects from SARS-CoV-2 and its tested variants

The Institute for Research in Biomedicine (IRB; Bellinzona, Switzerland), affiliated to the Università della Svizzera italiana (USI) developed a second-generation 'double antibody' that protects from SARS-CoV-2, the virus causing COVID-19, and all its tested variants. It also prevents the virus from mutating to resist the therapy.

24 Jan 2021

Transcriptional regulator BRD2 as a potential therapeutic target for COVID-19

A team of international scientists has demonstrated that therapeutic inhibition of a transcriptional regulator BRD2, required for the endogenous expression of angiotensin-converting enzyme 2 (ACE2), can potentially suppress severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is currently available on the bioRxiv* preprint server.

24 Jan 2021

Researchers show how to estimate long-term efficacy of COVID-19 vaccines

Researchers at the University of North Carolina and the Fred Hutchinson Cancer Research Center in Washington have developed a way to evaluate vaccines' long-term efficacy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

24 Jan 2021

New maintenance treatment for AML shows strong benefit for patients

Patients with acute myeloid leukemia (AML), the most common form of acute leukemia in adults, that has gone into remission following initial chemotherapy remain in remission longer and have improved overall survival when they are given a pill form of the cancer drug azacitidine as a maintenance treatment, according to a randomized, international phase 3 clinical trial for which Weill Cornell Medicine and NewYork-Presbyterian are trial sites.

22 Jan 2021

First-ever systematic review to understand geographic factors that affect HPV vaccination rates

Human papillomavirus (HPV) is the most common sexually transmitted infection, with an estimated 79 million Americans currently infected with the virus, according to the Centers for Disease Control and Prevention.

22 Jan 2021

Corning to highlight newest products in 3D cell culture portfolio at SLAS2021

Corning Incorporated will highlight its latest technologies that support the advancement of 3D cell culture, automation, and drug discovery at this year's virtual Society for Laboratory Automation and Screening (SLAS) conference on Jan. 25 through 27.

22 Jan 2021

UC research team uses zebrafish to study a gene mutation that causes congenital scoliosis

Popular in aquariums all over the world, the zebrafish is native to South Asia. But here in a Cincinnati Children's laboratory, the freshwater variant plays a vital role in scientific discovery.

22 Jan 2021

Researchers identify protein that may represent a safer treatment target for pancreatic cancer

Researchers from Queen Mary University of London, have identified a protein that may represent a novel therapeutic target for the treatment of pancreatic cancer.

22 Jan 2021

Study shows disproportionate impact of COVID-19 on Black and Asian populations

Patients of Asian and black backgrounds suffered disproportionate rates of premature death from COVID-19, according to a study of 1,737 patients by Queen Mary University of London and Barts Health NHS Trust.

22 Jan 2021

Dramatic changes seen in delivery of radiotherapy treatments during coronavirus pandemic

Dramatic changes were seen in the delivery of radiotherapy treatments for cancer during the first wave of the coronavirus pandemic in England.

22 Jan 2021

UC researchers test new combination therapy for head and neck cancer in animal models

Head and neck cancer is the sixth most common cancer worldwide, and while effective treatments exist, sadly, the cancer often returns.

22 Jan 2021

NCCN provides new guidance for COVID-19 vaccinations in people with cancer

The National Comprehensive Cancer Network put out new information today to provide guidance for COVID-19 vaccinations in people with cancer.

22 Jan 2021

Combination therapy shows potential for treating lung cancer

Most lung cancers are of a type called non-small-cell lung carcinoma (NSCLC). This type of cancer is relatively insensitive to chemotherapy, so NSCLC therapies are usually based on drug treatment.

22 Jan 2021

Does hypertension always lead to severe COVID-19?

Researchers have developed some prognostic factors to predict the severity of COVID-19 among hypertensive patients.

22 Jan 2021

EKF opens larger facility to increase production of key component for COVID-19 testing regime

EKF’s new facilities in Llandough, Cardiff, for the manufacture of PrimeStore® MTM viral transport media, enabling pathogenic samples to be collected and transported safely and easily in compliance with UN3373 packaging regulations.

From EKF Diagnostics 22 Jan 2021

Daily aspirin can reduce risk of colorectal cancer in adults

Regular aspirin use has clear benefits in reducing colorectal cancer incidence among middle-aged adults, but also comes with some risk, such as gastrointestinal bleeding. And when should adults start taking regular aspirin and for how long?

22 Jan 2021

Study: Medicated drops may help close small macular holes, prevent surgery to fix vision problems

Medicated drops may help close small macular holes over a two- to eight-week period, allowing some people to avoid surgery to fix the vision problem, a new study suggests.

22 Jan 2021

Sloan Kettering Institute researchers offer a new answer to 100-year-old cancer mystery

The year 2021 marks the 100th anniversary of a fundamental discovery that's taught in every biochemistry textbook. In 1921, German physician Otto Warburg observed that cancer cells harvest energy from glucose sugar in a strangely inefficient manner: rather than "burn" it using oxygen, cancer cells do what yeast do -- they ferment it.

22 Jan 2021

Cancer News and Research

Latest Cancer News and Research

Combining anti-tumor antibodies with standard-of-care improves therapeutic outcomes in cancer

Reduced expression of TBX15 in tumor tissue represents a prognostic biomarker for HCC patients

Second-generation double antibody protects from SARS-CoV-2 and its tested variants

Transcriptional regulator BRD2 as a potential therapeutic target for COVID-19

Researchers show how to estimate long-term efficacy of COVID-19 vaccines

New maintenance treatment for AML shows strong benefit for patients

First-ever systematic review to understand geographic factors that affect HPV vaccination rates

Corning to highlight newest products in 3D cell culture portfolio at SLAS2021

UC research team uses zebrafish to study a gene mutation that causes congenital scoliosis

Researchers identify protein that may represent a safer treatment target for pancreatic cancer

Study shows disproportionate impact of COVID-19 on Black and Asian populations

Dramatic changes seen in delivery of radiotherapy treatments during coronavirus pandemic

UC researchers test new combination therapy for head and neck cancer in animal models

NCCN provides new guidance for COVID-19 vaccinations in people with cancer

Combination therapy shows potential for treating lung cancer

Does hypertension always lead to severe COVID-19?

EKF opens larger facility to increase production of key component for COVID-19 testing regime

Daily aspirin can reduce risk of colorectal cancer in adults

Study: Medicated drops may help close small macular holes, prevent surgery to fix vision problems

Sloan Kettering Institute researchers offer a new answer to 100-year-old cancer mystery

Cancer Research - Second Edition eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Cancer News and Research

Latest Cancer News and Research

Cancer Research - Second Edition eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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