Chromosome News and Research

Latest Chromosome News and Research

Study shows long-term benefits for chronic myeloid leukemia patients receiving therapy with imatinib

CHU in Poitiers, France, yesterday announced results of a study showing that newly diagnosed patients with a certain form of leukemia who are treated early with imatinib are more likely to achieve complete cytogenetic responses (the elimination of leukemic cells, a major goal of therapy) and have improved long-term outcomes.

6 Dec 2004

New drug can successfully treat patients who have become resistant to Gleevec

A team of prominent researchers led by Charles Sawyers, M.D. and Moshe Talpaz, M.D., presented compelling clinical findings today showing that a new drug, BMS-354825, can successfully treat patients who have become resistant to Gleevec (the frontline therapy for chronic myelogenous leukemia, CML).

5 Dec 2004

Genetic mutations and cellular modifications may provide clues to the associations between slight genetic abnormalities and often fatal diseases

Modern research is delving deep into the human genome to find the answers to medical mysteries and, hopefully, cures for the most deadly diseases. According to four new studies presented during the 46th Annual Meeting of the American Society of Hematology

5 Dec 2004

Researchers step closer to cure for common childhood cancer

Acute lymphoblastic leukemia (ALL) is a malignant disease caused by the abnormal growth and development of white blood cells (WBC) in the bone marrow and blood. ALL is the most common cancer occurring in children with an annual rate of approximately 30 to 40 new cases per million.

5 Dec 2004

Human endogenous retroviruses (HERVs)

Human endogenous retroviruses (HERVs) have been the subject of a great deal of investigation in recent years. It has been established that HERVs cause some genetic diseases and there is strong circumstantial evidence for a link to some types of cancer and autoimmune diseases, but what else do we need to know about these unique organisms?

4 Dec 2004

African Americans more likely to carry genetic variants known to stimulate inflammatory response

Specific variants in genes that encode proteins regulating inflammation may hold a key to explaining a host of disease processes known to cause increased risk of illness and death among African Americans, according to a study from the University of Pittsburgh's Graduate School of Public Health (GSPH).

1 Dec 2004

Stress affects molecules believed to play a key role in cellular aging

There have been many studies that have shown that your health is greatly affected by how you react to stressful events in life-setbacks or deadlines at work, conflicts and losses at home.

29 Nov 2004

Researchers find mutations in a multifunctional protein cause Parkinsonism

A team of researchers at Mayo Clinic in Jacksonville, Fla. and colleagues in Canada and Germany have discovered a gene and six mutations of it that cause symptoms associated with Parkinson's disease and other neurodegenerative disorders.

18 Nov 2004

70% of cases of spina bifida are preventable by folic-acid supplementation

A seminar in this week’s issue of THE LANCET discusses the causes, symptoms, and treatments relating to spina bifida, and reinforces an important public-health message for women about to become pregnant

18 Nov 2004

Sex genes of infectious fungus closely resemble human Y chromosome

Fungi and animals, including humans, have a lot in common when it comes to the arrangement of genes that determine their sex, according to new work by Howard Hughes Medical Institute geneticists at the Duke University Medical Center.

10 Nov 2004

Discovery of new gene that protects against lung cancer

Cancer Research UK scientists have discovered a new gene that protects against lung cancer, according to a study published in the journal PNAS.

9 Nov 2004

Search for genetic key to corneal disease

A new federal grant focusing on painful inherited visual disorders that scar the cornea will allow researchers to narrow the genetic cause of one type of corneal dystrophy and to offer improved diagnosis of this family of diseases.

8 Nov 2004

Researchers find two locations in the human genome that may harbor genes that increase the risk of Alzheimer’s disease

Researchers at Columbia University Medical Center have found two locations in the human genome that may harbor genes that increase the risk of Alzheimer’s disease. If confirmed, they will be the first genes linked to Alzheimer’s disease since ApoE4 was discovered in 1993.

8 Nov 2004

Sensor protein that identifies DNA breaks and activates the p53 cell-death program has been identified

DNA breaks from radiation, toxic chemicals, or other environmental causes occur routinely in cells and, unless promptly and properly repaired, can lead to cancer-causing mutations.

4 Nov 2004

Improved risk classification for patients with acute lymphoblastic leukemia offers hope for eliminating irradiation

Improved risk classification for patients with acute lymphoblastic leukemia (ALL), coupled with more intensive intrathecal chemotherapy for high risk patients and the use of a drug called dexamethasone, could one day permit physicians to omit irradiation as a part of routine treatment.

1 Nov 2004

Scientists decode the genome sequence of Cryptosporidium hominis, one of the most common causes of waterborne diseases in humans

A team of scientists at Tufts University School of Veterinary Medicine has helped decode the genome sequence of Cryptosporidium hominis, an insidious parasite identified as one of the most common causes of waterborne diseases in humans and classified by the Centers for Disease Control and Prevention as a potential bioterrorist agent.

29 Oct 2004

Chromosome News and Research

Latest Chromosome News and Research

Study shows long-term benefits for chronic myeloid leukemia patients receiving therapy with imatinib

New drug can successfully treat patients who have become resistant to Gleevec

Genetic mutations and cellular modifications may provide clues to the associations between slight genetic abnormalities and often fatal diseases

Researchers step closer to cure for common childhood cancer

Human endogenous retroviruses (HERVs)

African Americans more likely to carry genetic variants known to stimulate inflammatory response

Stress affects molecules believed to play a key role in cellular aging

Researchers find mutations in a multifunctional protein cause Parkinsonism

70% of cases of spina bifida are preventable by folic-acid supplementation

Sex genes of infectious fungus closely resemble human Y chromosome

Discovery of new gene that protects against lung cancer

Search for genetic key to corneal disease

Researchers find two locations in the human genome that may harbor genes that increase the risk of Alzheimer’s disease

Sensor protein that identifies DNA breaks and activates the p53 cell-death program has been identified

Improved risk classification for patients with acute lymphoblastic leukemia offers hope for eliminating irradiation

Scientists decode the genome sequence of Cryptosporidium hominis, one of the most common causes of waterborne diseases in humans

New insight into the role of the breast cancer gene known as BRCA2

Australian platypus research has implications for understanding the evolution of human sex determination

Newly discovered gene could be a significant contributor to diabetes in Americans

Gene mutation causes Parkinson's disease in some families

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Chromosome News and Research

Latest Chromosome News and Research

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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