Chromosome News and Research

Latest Chromosome News and Research

New insights on DNA replication can help develop novel cancer treatments

A study by the Centre for Chromosome Biology at NUI Galway, Ireland, in partnership with the University of Zurich, has uncovered new insights into how the replication of DNA occurs which can be applied to help develop novel cancer treatments.

10 Jun 2020

New Canadian study investigates how cancer adapts its metabolism to overcome therapies

Knowing what cancer will do next could lessen the likelihood of it becoming resistant to treatment. A new Canadian study investigates how cancer adapts its metabolism to potentially overcome therapies still in development.

8 Jun 2020

New images of LSD1 enzyme in action shed light on gene regulation

New images of an enzyme in action as it interacts with the chromosome could provide important insight into how cells--including cancer cells--regulate their genes.

5 Jun 2020

SARS-CoV-2 gene deletions may cause milder infections and increase human-to-human transmission

In their recent paper released on the bioRxiv preprint server, a research group from Spain demonstrated how genome changes and deletions in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could represent a strategy of natural selection used for lessening the impact of infection in order to increase viral transmission potential.

4 Jun 2020

New studies provide insights into DNA crossovers in egg and sperm cells

In the famous words of movie character Forrest Gump, "Life is like a box of chocolates; you never know what you're gonna get."

4 Jun 2020

How COVID-19 affects people with Down Syndrome

A new study published in June 2020 on the preprint online server medRxiv reports on the increased risk of COVID-19 in Down Syndrome (DS) and certain characteristic features that are found in this population segment.

3 Jun 2020

Blood group type may affect susceptibility to COVID-19 respiratory failure

A group of over 120 researchers from various institutions across Europe has performed the first genome-wide association study to reveal host genetic factors that may contribute to respiratory failure in cases of coronavirus disease 209 (COVID-19).

3 Jun 2020

Researchers discover genetic cause of 'differences in sexual development'

Researchers at the Francis Crick Institute, the Institut Pasteur and their clinical collaborators have identified a cause of testicular tissue developing in people with female chromosomes.

1 Jun 2020

New genetic engineering technique sets the stage for advances in medicine and beyond

From bacteria-made insulin that obviates the use of animal pancreases to a better understanding of infectious diseases and improved treatments, genetic engineering of bacteria has redefined modern medicine. Yet, serious limitations remain that hamper| progress in numerous other areas.

30 May 2020

Targeted therapy pralsetinib shows high response rates in patients with RET fusion-positive cancers

The targeted therapy pralsetinib appears to have high response rates and durable activity in patients with a broad variety of tumors harboring RET gene fusions, according to results from the international Phase I/II ARROW trial, led by researchers at The University of Texas MD Anderson Cancer Center.

29 May 2020

Study sheds light on homologous recombination of DNA strands

As chromosomes go, X and Y make an unlikely pair. The X is large and contains thousands of genes critical for life. The Y, by contrast, is little more than a nub.

29 May 2020

Mouse model mimics clinical course and pathology observed in COVID-19 patients

A mouse model of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reproduces features observed in human patients, researchers report May 26 in the journal Cell Host & Microbe.

27 May 2020

Researchers investigate the early development of ovarian cancer

Researchers from the group of Hans Clevers at the Hubrecht Institute have modeled the development and progression of high-grade serous ovarian cancer in mini-versions of the female reproductive organs of the mouse.

27 May 2020

New genomic method helps obtain high-resolution maps of DNA in the cell nucleus

Researchers at Karolinska Institutet in Sweden have developed a new sequencing method that makes it possible to map how DNA is spatially organised in the cell nucleus - revealing which genomic regions are at higher risk of mutation and DNA damage.

26 May 2020

Researchers recombine entire chromosomes with CRISPR/Cas technology

The CRISPR/Cas molecular scissors work like a fine surgical instrument and can be used to modify genetic information in plants.

25 May 2020

Study uncovers the role of DNA repair in preserving egg quality

A Monash University study has uncovered the role DNA repair plays in preserving egg quality, offering hope for women whose eggs may be damaged through treatments such as radiation and chemotherapy.

22 May 2020

Novel biomarkers linked to improved outcomes with immunotherapy in metastatic breast cancer

Two novel biomarkers have been found to correlate with improved outcomes with immunotherapy in metastatic breast cancer and may help to identify the patients most likely to benefit from this treatment, according to exploratory studies reported at the ESMO Breast Cancer Virtual Meeting 2020.

22 May 2020

Research demonstrates self-synthesis and assembly of 30S subunit of ribosome

As the cell's protein factory, the ribosome is the only natural machine that manufactures its own parts. That is why understanding how the machine, itself, is made, could unlock the door to everything from understanding how life develops to designing new methods of drug production.

21 May 2020

DZD researchers discover additional genetic cause for non-alcoholic fatty liver disease

In Germany about 18 million people suffer from non-alcoholic fatty liver. The causes of this disease are manifold and include environmental as well as genetic factors.

19 May 2020

Gene variants can increase risk of schizophrenia, shows study

Variants in a gene of the human immune system cause men and women to have different vulnerabilities to the autoimmune diseases lupus and Sjögren's syndrome, according to findings published in the journal Nature.

19 May 2020

Chromosome News and Research

Latest Chromosome News and Research

New insights on DNA replication can help develop novel cancer treatments

New Canadian study investigates how cancer adapts its metabolism to overcome therapies

New images of LSD1 enzyme in action shed light on gene regulation

SARS-CoV-2 gene deletions may cause milder infections and increase human-to-human transmission

New studies provide insights into DNA crossovers in egg and sperm cells

How COVID-19 affects people with Down Syndrome

Blood group type may affect susceptibility to COVID-19 respiratory failure

Researchers discover genetic cause of 'differences in sexual development'

New genetic engineering technique sets the stage for advances in medicine and beyond

Targeted therapy pralsetinib shows high response rates in patients with RET fusion-positive cancers

Study sheds light on homologous recombination of DNA strands

Mouse model mimics clinical course and pathology observed in COVID-19 patients

Researchers investigate the early development of ovarian cancer

New genomic method helps obtain high-resolution maps of DNA in the cell nucleus

Researchers recombine entire chromosomes with CRISPR/Cas technology

Study uncovers the role of DNA repair in preserving egg quality

Novel biomarkers linked to improved outcomes with immunotherapy in metastatic breast cancer

Research demonstrates self-synthesis and assembly of 30S subunit of ribosome

DZD researchers discover additional genetic cause for non-alcoholic fatty liver disease

Gene variants can increase risk of schizophrenia, shows study

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Chromosome News and Research

Latest Chromosome News and Research

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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