Chronic Kidney Disease News and Research

Latest Chronic Kidney Disease News and Research

Toxin-induced insulin resistance combated in mice

French researchers have found that a protein-bound uremic toxin, p-cresyl sulfate, contributes to the development of insulin resistance in mice, providing a new potential therapeutic target for treating chronic kidney disease, they say.

4 Jan 2013

AMAG seeks FDA sNDA approval for Feraheme Injection

AMAG Pharmaceuticals, Inc. today announced that it has submitted a supplemental new drug application (sNDA) to the United States Food and Drug Administration (FDA) for Feraheme (ferumoxytol) Injection for Intravenous (IV) use.

25 Dec 2012

Targeting PCS may help improve health of patients with chronic kidney disease

Insulin resistance, or prediabetes, in individuals with kidney disease may be caused by the progressive retention of certain compounds that are normally excreted by the kidneys in healthy individuals, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

21 Dec 2012

Partial nephrectomy maintains renal function in cT1a RCC

Partial nephrectomy offers a similar magnitude of benefit in patients with clinical T1b versus cT1a renal cell carcinoma, Japanese researchers have shown.

17 Dec 2012

ETA receptor antagonism reduces novel cardiovascular risk factors in patients with CKD

Blocking the receptor for proteins that constrict blood vessels reduces markers of heart-related problems in patients with chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

14 Dec 2012

Mineral metabolism abnormalities may increase risk of kidney failure among African Americans

Abnormalities of mineral metabolism worsen with progressive chronic kidney disease (CKD) and are linked with a higher risk for kidney failure among African Americans, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

14 Dec 2012

Astellas, FibroGen commence FG-4592/ASP1517 Phase 3 clinical program in CKD anemia

FibroGen, Inc., and Astellas Pharma Inc., announced today the initiation of the first clinical study in the Phase 3 clinical development program of FG-4592/ASP1517, an orally administered small molecule, for treatment of anemia associated with chronic kidney disease ("CKD") in patients not on dialysis and on dialysis, to support approval in the U.S. and Europe.

12 Dec 2012

AMAG presents new data from two ferumoxytol phase III trials on IDA at ASH annual meeting

AMAG Pharmaceuticals, Inc. today announced that new data from two pivotal phase III clinical trials were presented at the American Society of Hematology's (ASH) annual meeting in Atlanta, Georgia.

11 Dec 2012

Modified CKD model aids risk prediction in African Americans

Screening African Americans for microalbuminuria at either 5- or 10-year intervals would be highly cost-effective using a modified version of the CKD Health Policy Model, US researchers report.

7 Dec 2012

Study reveals increase in incidence of dialysis-requiring acute kidney injury

Acute kidney injury (AKI), an abrupt or rapid decline in kidney function, is a serious and increasingly prevalent condition that can occur after major infections, major surgery, or exposure to certain medications.

7 Dec 2012

Baxter enters definitive agreement to acquire Gambro

Baxter International Inc. has entered into a definitive agreement to acquire Gambro AB, a privately held dialysis product company based in Lund, Sweden, for total consideration of 26.5 billion SEK (approximately $4.0 billion USD at current exchange rates).

From Baxter International Inc. 5 Dec 2012

NOXXON commences NOX-H94 Phase IIa trial to treat anemia of chronic disease

NOXXON Pharma today announced the treatment of the first patients in a Phase IIa clinical trial of its anti-hepcidin Spiegelmer NOX-H94 to treat anemia associated with chronic disease.

5 Dec 2012

DaVita acquires Tulips Dialysis Centre; opens two new joint venture centers in Malaysia

DaVita, a leading provider of kidney care services for those diagnosed with chronic kidney disease (CKD), today announced the acquisition of Tulips Dialysis Centre and has opened two new joint venture centers in Malaysia.

3 Dec 2012

African Americans experience faster progression of CKD during later stages

Among individuals with chronic kidney disease (CKD), African Americans experience faster progression of the disease during later stages compared with other races, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

30 Nov 2012

Kidney disease measures on mortality, ESRD unaffected by age

Regardless of age, estimated glomerular filtration rate and high albuminuria are linked to death and end-stage renal disease, say US scientists who found a lower relative but higher absolute mortality risk difference at older age.

23 Nov 2012

Texting service helps patients reduce their blood pressure

A simple telehealth intervention could be an effective way to reduce blood pressure in patients, research suggests.

19 Nov 2012

Decreased cognitive functioning associated with deterioration in kidney function

Decreased kidney function is associated with decreased cognitive functioning in areas such as global cognitive ability, abstract reasoning and verbal memory, according to a study led by Temple University. This is the first study describing change in multiple domains of cognitive functioning in order to determine which specific abilities are most affected in individuals with impaired renal function.

19 Nov 2012

Chronic Kidney Disease News and Research

Latest Chronic Kidney Disease News and Research

Toxin-induced insulin resistance combated in mice

AMAG seeks FDA sNDA approval for Feraheme Injection

Targeting PCS may help improve health of patients with chronic kidney disease

Partial nephrectomy maintains renal function in cT1a RCC

ETA receptor antagonism reduces novel cardiovascular risk factors in patients with CKD

Mineral metabolism abnormalities may increase risk of kidney failure among African Americans

Astellas, FibroGen commence FG-4592/ASP1517 Phase 3 clinical program in CKD anemia

AMAG presents new data from two ferumoxytol phase III trials on IDA at ASH annual meeting

Modified CKD model aids risk prediction in African Americans

Study reveals increase in incidence of dialysis-requiring acute kidney injury

Baxter enters definitive agreement to acquire Gambro

NOXXON commences NOX-H94 Phase IIa trial to treat anemia of chronic disease

DaVita acquires Tulips Dialysis Centre; opens two new joint venture centers in Malaysia

African Americans experience faster progression of CKD during later stages

Kidney disease measures on mortality, ESRD unaffected by age

Texting service helps patients reduce their blood pressure

Decreased cognitive functioning associated with deterioration in kidney function

Cinacalcet failure raises trial conduct issues

Tengion receives U.S. patent allowance titled ‘Isolated Renal Cells and Uses Thereof’

Studies provide new information on diet and blood pressure in kidney disease patients

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Chronic Kidney Disease News and Research

Latest Chronic Kidney Disease News and Research

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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