Cirrhosis News and Research

Latest Cirrhosis News and Research

UT Southwestern scientists identify genetic mutations that contribute to nonalcoholic fatty liver disease

Using a genetic screening platform developed by a UT Southwestern Nobel Laureate, scientists with the Center for the Genetics of Host Defense at UT Southwestern Medical Center have identified genetic mutations that contribute to nonalcoholic fatty liver disease (NAFLD), providing a potential future target for therapeutic interventions.

9 Sep 2022

Cedars-Sinai investigators create new blood test for early detection of common liver cancer

Cedars-Sinai Cancer investigators have created a blood test that uses a technology made commonly available during the COVID-19 pandemic to detect the most common form of liver cancer-;at an early enough stage that cure is possible.

30 Aug 2022

Immune therapy may be an alternate therapeutic approach for treating chronic hepatitis B

Hepatitis B virus (HBV) infection is global in nature and induces several incredible liver diseases, such as chronic hepatitis B (CHB), cirrhosis of the liver (LC) and hepatocellular carcinoma (HCC). A total of 882,000 patients died of HBV-related liver diseases in 2019.

25 Aug 2022

Researchers find rebleeding rates and predictors for obscure gastrointestinal bleeding

Obscure gastrointestinal bleeding (OGIB) is defined as gastrointestinal bleeding from a source that cannot be determined even after upper or lower gastrointestinal endoscopy is performed.

19 Aug 2022

The QCOVID4 algorithm developed using data from the Omicron wave identifies those at highest risk of severe COVID-19 outcomes

A recent article illustrated the derivation and validation of the QCOVID4 risk determination algorithm for predicting COVID-19 hospitalization and death risk in England.

18 Aug 2022

Elevated acetate levels reprogram gut microbiota during alcohol intake

Chronic alcohol use is a major cause of liver damage and death: Approximately 30,000 persons in the United States die annually from alcoholic liver diseases, such as cirrhosis.

11 Aug 2022

What is the association between polyfluoroalkyl substance exposure and risk of non-viral hepatocellular carcinoma?

The current study, published online in the journal JHEP Reports, looks at PFAS, which are endocrine disruptors and potential hepatotoxins.

11 Aug 2022

Vitamin B12, folic acid supplements could potentially halt or reverse advanced form of fatty liver disease

Scientists at Duke-NUS Medical School in Singapore have uncovered a mechanism that leads to an advanced form of fatty liver disease-;and it turns out that vitamin B12 and folic acid supplements could reverse this process.

5 Aug 2022

Extracellular vesicle-based surface protein assay likely to lead to a better way to detect early-stage hepatocellular carcinoma

Primary liver cancer, the third-leading cause of cancer-related death worldwide, takes more than 30,000 lives in the United States each year. The high mortality rates can be attributed in part to the fact that a significant portion of the patients are detected at a late stage, when potentially curative treatments are no longer an option. Unfortunately, today's screening methods are not able to routinely provide accurate, early detection.

5 Aug 2022

Inexpensive, self-driven microfluidic chip rapidly detects Hepatitis C virus in about 45 minutes

Hepatitis C affects more than 354 million people worldwide. About 75 to 85 percent of people who have it get a long-term infection referred to as chronic Hepatitis C. Left untreated, it could lead to cirrhosis, liver cancer or liver failure.

3 Aug 2022

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

In this interview, we speak to Tom Kostrzewski, VP of Science and Technology at CN Bio, about their organ-on-a-chip product and the future of drug discovery.

From CN-Bio 3 Aug 2022

NIH updates its strategic plan for hepatitis B research

The National Institutes of Health has updated its Strategic Plan for NIH Research to Cure Hepatitis B, a roadmap for ending the hepatitis B epidemic, focused on developing a cure as well as improved strategies for vaccination, screening and follow-up care.

1 Aug 2022

Transplant remains the standard of care for liver cancer patients, regardless of age

Physicians and researchers from UK HealthCare's Transplant Center and the University of Kentucky Markey Cancer Center conducted a study of patients over the age of 70 with a type of liver cancer called hepatocellular carcinoma (HCC) and how the outcomes of ablative treatments compare to liver transplants.

28 Jul 2022

World Hepatitis Day 2022: Why Accelerating the Fight Against Hepatitis Cannot Wait

In our latest interview, News-Medical speaks to Simon Parker, an infectious disease specialist, about hepatitis C diagnostics and testing, as well as why the global fight against hepatitis cannot wait.

28 Jul 2022

Years of life lost associated with leading causes of US death during the first 20 months of the COVID-19 pandemic

Researchers estimated the years of life lost during the COVID-19 pandemic in the United States.

28 Jul 2022

Lactating mice expose their feeding pups to triclosan resulting in early signs of liver damage

In mouse studies, researchers at University of California San Diego School of Medicine report that lactating mothers expose their feeding pups to triclosan, an antimicrobial commonly used in consumer products, resulting in early signs of liver damage that can eventually lead to more serious impairment and illness, such as nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH).

28 Jul 2022

'Western style' diet high in fat and sugar can negatively affect breast milk and baby's health

A diet high in sugar and fat such as burgers, fries and fizzy drinks can negatively affect a new mother's breast milk and baby's health even before the child is conceived.

27 Jul 2022

SLU and industry partners report the first effective drug to treat rare, genetic liver disease

Researchers at Saint Louis University's School of Medicine, in collaboration with Arrowhead Pharmaceuticals and Takeda Pharmaceuticals, report the first effective drug to treat a rare, genetic liver disease that formerly could only be treated with a liver transplant.

26 Jul 2022

What is the optimal alcohol consumption level to minimize health loss?

Researchers performed a population-scale analysis of alcohol consumption by amount, age, gender, region, and year to estimate the theoretical minimum risk exposure level (TMREL) and the non-drinker equivalence (NDE).

19 Jul 2022

Alcohol consumption does not provide any health benefits, presents many risks for young people

Young people face higher health risks from alcohol consumption than older adults, according to a new analysis published in The Lancet.

15 Jul 2022

Cirrhosis News and Research

Latest Cirrhosis News and Research

UT Southwestern scientists identify genetic mutations that contribute to nonalcoholic fatty liver disease

Cedars-Sinai investigators create new blood test for early detection of common liver cancer

Immune therapy may be an alternate therapeutic approach for treating chronic hepatitis B

Researchers find rebleeding rates and predictors for obscure gastrointestinal bleeding

The QCOVID4 algorithm developed using data from the Omicron wave identifies those at highest risk of severe COVID-19 outcomes

Elevated acetate levels reprogram gut microbiota during alcohol intake

What is the association between polyfluoroalkyl substance exposure and risk of non-viral hepatocellular carcinoma?

Vitamin B12, folic acid supplements could potentially halt or reverse advanced form of fatty liver disease

Extracellular vesicle-based surface protein assay likely to lead to a better way to detect early-stage hepatocellular carcinoma

Inexpensive, self-driven microfluidic chip rapidly detects Hepatitis C virus in about 45 minutes

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

NIH updates its strategic plan for hepatitis B research

Transplant remains the standard of care for liver cancer patients, regardless of age

World Hepatitis Day 2022: Why Accelerating the Fight Against Hepatitis Cannot Wait

Years of life lost associated with leading causes of US death during the first 20 months of the COVID-19 pandemic

Lactating mice expose their feeding pups to triclosan resulting in early signs of liver damage

'Western style' diet high in fat and sugar can negatively affect breast milk and baby's health

SLU and industry partners report the first effective drug to treat rare, genetic liver disease

What is the optimal alcohol consumption level to minimize health loss?

Alcohol consumption does not provide any health benefits, presents many risks for young people

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Cirrhosis News and Research

Latest Cirrhosis News and Research

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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