Cytokines News and Research

Latest Cytokines News and Research

Landes Bioscience releases special issue on sepsis

A special issue on sepsis has been released by the publisher Landes Bioscience (Austin, TX USA). The articles contained in this special issue of the journal Virulence have been authored by world-class investigators and provide new insights into both the pathogen-related factors and the host defense mechanisms that lead to septic shock and contribute to its resolution or fatal outcome.

7 Jan 2014

Macrophages invade diabetic pancreatic tissue during early stages of type 2 diabetes

As people's waistlines increase, so does the incidence of type 2 diabetes. Now scientists have a better understanding of exactly what happens in the body that leads up to type 2 diabetes, and what likely causes some of the complications related to the disease. Specifically, scientists from Denmark have found that in mice, macrophages, a specific type of immune cell, invade the diabetic pancreatic tissue during the early stages of the disease.

2 Jan 2014

Study explores how genetic sequencing can help fight new strains of flu

Published in the Journal Proceedings of the National Academy of Sciences, senior author, Associate Professor Katherine Kedzierska from the Department of Microbiology and Immunology said that being able to predict which patients will be more susceptible to the emerging influenza strain, will allow clinicians to better manage an early intervention strategy.

24 Dec 2013

Asthma link to mood disorders strengthened

Results from a prospective study support a relationship between asthma in adolescence and future diagnosis of mood disorders.

24 Dec 2013

Autoimmune clue to narcolepsy

Researchers have identified immune cells in patients with narcolepsy that react against hypocretin, the lack of which causes the disorder.

20 Dec 2013

Takeda to acquire exclusive license to develop Natrogen's Natura-alpha compound

Takeda Pharmaceutical Company Limited and Natrogen Therapeutics International, Inc. jointly announced today an agreement whereby Takeda will acquire an exclusive license to develop Natrogen's Natura-alpha compound as well as an option to acquire Natrogen. Natura-alpha is a synthetic small molecule oral compound that is believed to inhibit pro-inflammatory cytokine expression, which may help to reduce gastrointestinal inflammation. Natura-alpha is currently in Phase 2 development for the treatment of ulcerative colitis.

20 Dec 2013

Scientists identify protein complex essential for jumpstarting immune response during infection

St. Jude Children's Research Hospital scientists have identified a protein complex that is essential for jumpstarting the immune response during the critical first 24 hours of an infection. The research appears in the current issue of the scientific journal Immunity.

17 Dec 2013

Elevated BACE1 activity in mild cognitive impairment could be early indicator of AD, says study

The critical enzyme beta-secretase1 (BACE1) is known to be elevated in brains with sporadic Alzheimer disease (AD). Scientists have now found increased levels of BACE1 in brains with mild cognitive impairment (MCI), suggesting that BACE1 activity is important for conversion of mild cognitive impairment to AD and may be an early indicator of AD.

12 Dec 2013

Researchers uncover biological factor that may contribute to disparities in prostate cancer incidence

Researchers have uncovered a potential biological factor that may contribute to disparities in prostate cancer incidence and mortality between African-American and non-Hispanic white men in the United States, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.

9 Dec 2013

Scientists identify key factor for limiting inflammatory responses, particularly in skin

Sanford-Burnham scientists have identified the B and T Lymphocyte Attenuator (BTLA) inhibitory receptor as a key factor in limiting inflammatory responses, particularly in the skin. The study, published online today in Immunity, provides clarity on how T cells get fired up to protect against pathogens, and then cool down to restore immune homeostasis.

6 Dec 2013

Soligenix initiates orBec Phase 2 study for GI manifestations of chronic GVHD

Soligenix, Inc., a clinical stage biopharmaceutical company focused on developing products to treat serious inflammatory diseases where there remains an unmet medical need, as well as developing several biodefense vaccines and therapeutics, announced today that it has initiated a Phase 2, randomized, double-blind, placebo-controlled study evaluating orBec (oral beclomethasone 17,21-dipropionate or BDP) as a treatment for the gastrointestinal manifestations of chronic Graft-versus-Host disease.

2 Dec 2013

Childhood asthma, eczema linked to adolescent psychotic experiences

UK research indicates that children with asthma and eczema are significantly more likely to have psychotic experiences during adolescence, boosting a previously reported relationship between schizophrenia and atopic disorders.

28 Nov 2013

Inhibition of complement system plays major role in xenograft rejection

Researchers at the Bellvitge Institute of Biomedical Research (IDIBELL) led by Cristina Costa from the New Therapies on Genes and Transplantation group have shown that inhibition of one of the basic components of the complement system protects chondrocytes (cartilage cells) from porcine rejection of xenotransplantation (transplantation between animals of different species).

27 Nov 2013

Researchers identify immune cell protein that sets off body's initial response against viral infection

A Massachusetts General Hospital-led research team has identified an immune cell protein that is critical to setting off the body's initial response against viral infection. The report that will be published in an upcoming issue of Nature Immunology and is receiving early online release describes finding that a protein called GEF-H1 is essential to the ability of macrophages - major contributors to the innate immune system - to respond to viral infections like influenza.

25 Nov 2013

Mouse study highlights importance of microorganisms in optimal cancer treatment outcomes

...

22 Nov 2013

'Quitting cold turkey' can lead to mental decline, shows study

Can quitting drugs without treatment trigger a decline in mental health? That appears to be the case in an animal model of morphine addiction. Georgetown University Medical Center researchers say their observations suggest that managing morphine withdrawal could promote a healthier mental state in people.

13 Nov 2013

Revalesio to conduct RNS60 Phase IIa clinical trial in RRMS patients

Revalesio Corporation is pleased to announce a new collaboration with noted neurologist Dr. Roland Martin, Head of Neuroimmunology and MS Research at the Department of Neurology, University Hospital Zurich. Dr. Martin will be conducting a Phase IIa clinical trial of RNS60 in patients with relapsing-remitting multiple sclerosis.

12 Nov 2013

Australian scientists unravel mystery behind immune system memory

While the principle of immune memory has been known for decades, the exact molecular mechanisms underpinning it have remained a mystery. Australian scientists have now unraveled part of that mystery, identifying the role of a gene called STAT3, which acts as a kind of roundabout, directing chemical messenger molecules to various destinations.

12 Nov 2013

Early-life stress suspected to contribute to development of chronic pain in adulthood

Childhood neglect and abuse, whether physical or psychological, confers a lifetime vulnerability to stress, anxiety, and mood problems. Such early-life stress is also suspected to contribute to the development of chronic pain in adulthood.

6 Nov 2013

Interaction between fat cells and bacterial toxins can lead to chronic inflammation

Making fat cells immortal might seem like a bad idea to most people, but for a team of University of Iowa scientists it was the ideal way to study how the interaction between bacteria and fat cells might contribute to diabetes.

31 Oct 2013

Cytokines News and Research

Latest Cytokines News and Research

Landes Bioscience releases special issue on sepsis

Macrophages invade diabetic pancreatic tissue during early stages of type 2 diabetes

Study explores how genetic sequencing can help fight new strains of flu

Asthma link to mood disorders strengthened

Autoimmune clue to narcolepsy

Takeda to acquire exclusive license to develop Natrogen's Natura-alpha compound

Scientists identify protein complex essential for jumpstarting immune response during infection

Elevated BACE1 activity in mild cognitive impairment could be early indicator of AD, says study

Researchers uncover biological factor that may contribute to disparities in prostate cancer incidence

Scientists identify key factor for limiting inflammatory responses, particularly in skin

Soligenix initiates orBec Phase 2 study for GI manifestations of chronic GVHD

Childhood asthma, eczema linked to adolescent psychotic experiences

Inhibition of complement system plays major role in xenograft rejection

Researchers identify immune cell protein that sets off body's initial response against viral infection

Mouse study highlights importance of microorganisms in optimal cancer treatment outcomes

'Quitting cold turkey' can lead to mental decline, shows study

Revalesio to conduct RNS60 Phase IIa clinical trial in RRMS patients

Australian scientists unravel mystery behind immune system memory

Early-life stress suspected to contribute to development of chronic pain in adulthood

Interaction between fat cells and bacterial toxins can lead to chronic inflammation

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Cytokines News and Research

Latest Cytokines News and Research

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Newsletters you may be interested in