Cytokines News and Research

Latest Cytokines News and Research

Multiple studies examine ideal biomarkers for Huntington's disease

While Huntington's disease (HD) is currently incurable, the HD research community anticipates that new disease-modifying therapies in development may slow or minimize disease progression. The success of HD research depends upon the identification of reliable and sensitive biomarkers to track disease and evaluate therapies, and these biomarkers may eventually be used as outcome measures in clinical trials. Biomarkers could be especially helpful to monitor changes during the time prior to diagnosis and appearance of overt symptomatology.

21 May 2013

Understanding the role of dsRNA in antiviral host defense systems

Animals, insects, and plants use a variety of sensing mechanisms to detect invading pathogens such as viruses. One complex and effective antiviral defense system they share is based on recognition of double-stranded RNA, often produced when a virus invades a host cell.

20 May 2013

Galapagos, AbbVie announce extension of GLPG0634 clinical development collaboration

Galapagos NV and AbbVie announced today an extension of their GLPG0634 clinical development collaboration to include Crohn's disease. Galapagos will fund and complete a Phase 2 program in Crohn's disease, which is designed to facilitate rapid progression into Phase 3.

17 May 2013

Implications for manipulating immune response for some inflammatory disorders

Cytokines are molecules produced by immune cells that induce the migration of other cells to sites of infection or injury, promote the production of anti-microbial agents, and signal the production of inflammatory mediators.

14 May 2013

Idera to present data from Phase 2 trial of IMO-3100 in patients with psoriasis at IID 2013

Idera Pharmaceuticals today announced presentation of data from its randomized, double-blind, placebo-controlled Phase 2 trial that showed improvements from baseline of up to 90% in Psoriasis Area Severity Index scores in patients with moderate to severe plaque psoriasis following four weeks of treatment with the Toll-like Receptor antagonist IMO-3100.

8 May 2013

Isis begins clinical study of ISIS-STAT3 in patients with metastatic liver cancer

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 1b/2a clinical study of ISIS-STAT3Rx in patients with advanced metastatic hepatocellular carcinoma (HCC).

7 May 2013

Scientists spell out pivotal role of Peli1 in mouse model of multiple sclerosis

Scientists have identified an influential link in a chain of events that leads to autoimmune inflammation of the central nervous system in a mouse model of multiple sclerosis.

3 May 2013

Specific inflammatory pattern found in patients with pneumonia and COPD

Patients with community-acquired pneumonia on a background of chronic obstructive pulmonary disease have a different early inflammatory pattern than patients with CAP only, a prospective study shows.

30 Apr 2013

Specific inflammatory pattern found in patients with pneumonia and COPD

Patients with community-acquired pneumonia on a background of chronic obstructive pulmonary disease have a different early inflammatory pattern than patients with CAP only, a prospective study shows.

29 Apr 2013

Opsona raises €33M in oversubscribed financing round

Opsona Therapeutics Limited, the innate immune drug development company, today announced that it has raised €33 million (US $ 43 million) in an oversubscribed Series C financing.

29 Apr 2013

Transgene announces pre-clinical data of TG1050 for treatment of chronic hepatitis B infection

Transgene SA, a biopharmaceutical company that develops targeted immunotherapy products to treat major unmet medical needs in cancer and chronic infectious diseases, announced pre-clinical data obtained with its novel immunotherapeutic, TG1050, to treat chronic hepatitis B infection.

29 Apr 2013

GI nematode infections combat obesity and improve related metabolic disorders

Researchers at the University of Maryland School of Medicine, Baltimore, have shown in a mouse model that infection with nematodes (also known as roundworms) can not only combat obesity but ameliorate related metabolic disorders.

26 Apr 2013

Potential therapies for smell loss

Snot. It's not something most of us spend a lot of time thinking about, but, for a team of researchers in Washington, D.C., it's front and center.

22 Apr 2013

High dietary salt combined with ulcer infection greatly increases risk of gastric cancer

Numerous epidemiologic studies have shown that a diet high in salt is associated with an increased risk of gastric cancer.

19 Apr 2013

Arthritis drug reduces dry eye disease

Dry eye disease (DED) is a common condition that causes discomfort, visual disturbance and potentially damaging ocular surface inflammation that greatly impacts a person's quality of life.

19 Apr 2013

KYTHERA Biopharmaceuticals reports positive results from Phase IIb study of ATX-101

KYTHERA Biopharmaceuticals, Inc. today presented positive results that found MRI measurements of patients treated with ATX-101 demonstrated a statistically significant reduction in submental fat, commonly known as double chin, during an oral session at The Aesthetic Meeting 2013, organized by the American Society for Aesthetic Plastic Surgery, April 11-16, New York, NY.

15 Apr 2013

Researchers develop new strategy to control inflammation without serious side effects

A potential new strategy to developing new drugs to control inflammation without serious side effects has been found by Georgia State University researchers and international colleagues.

10 Apr 2013

Research findings provide insight into severe bacterial infectious diseases

UT Southwestern Medical Center researchers report that a pathogen annually blamed for an estimated 90 million cases of food-borne illness defeats a host's immune response by using a fat-snipping enzyme to cut off cellular communication.

5 Apr 2013

RayBiotech's array system identifies key factors involved in dissemination of leprosy infection

RayBiotech, Inc. announced today that the application of its Mouse Cytokine Antibody Array has enabled the identification of key factors involved in the dissemination of leprosy infection in humans.

4 Apr 2013

Ulcerative colitis and Crohn’s disease treatments: an interview with Dr Parikh, vice president, general medicine, Takeda

Ulcerative colitis (UC) and Crohn’s disease (CD) are both relapsing and remitting chronic diseases of bowel inflammation. By that I mean they flare and physicians try to get the flare under control and try to induce remission. However, despite a number of treatments available, they tend to relapse.

From Takeda 3 Apr 2013

Cytokines News and Research

Latest Cytokines News and Research

Multiple studies examine ideal biomarkers for Huntington's disease

Understanding the role of dsRNA in antiviral host defense systems

Galapagos, AbbVie announce extension of GLPG0634 clinical development collaboration

Implications for manipulating immune response for some inflammatory disorders

Idera to present data from Phase 2 trial of IMO-3100 in patients with psoriasis at IID 2013

Isis begins clinical study of ISIS-STAT3 in patients with metastatic liver cancer

Scientists spell out pivotal role of Peli1 in mouse model of multiple sclerosis

Specific inflammatory pattern found in patients with pneumonia and COPD

Specific inflammatory pattern found in patients with pneumonia and COPD

Opsona raises €33M in oversubscribed financing round

Transgene announces pre-clinical data of TG1050 for treatment of chronic hepatitis B infection

GI nematode infections combat obesity and improve related metabolic disorders

Potential therapies for smell loss

High dietary salt combined with ulcer infection greatly increases risk of gastric cancer

Arthritis drug reduces dry eye disease

KYTHERA Biopharmaceuticals reports positive results from Phase IIb study of ATX-101

Researchers develop new strategy to control inflammation without serious side effects

Research findings provide insight into severe bacterial infectious diseases

RayBiotech's array system identifies key factors involved in dissemination of leprosy infection

Ulcerative colitis and Crohn’s disease treatments: an interview with Dr Parikh, vice president, general medicine, Takeda

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Cytokines News and Research

Latest Cytokines News and Research

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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