Diabetes News and Research

Latest Diabetes News and Research

Two new methods could accelerate development of improved antisense drugs

Powerful antisense drugs that target disease-associated genes to block their expression can be used to treat a broad range of diseases. Though antisense therapy has been proven effective, challenges remain in ensuring that the drugs reach their intended targets.

2 Feb 2013

Experts contemplate whether Medicare should pay for Alzheimer's test

Also in the news, Astra Zeneca and Bristol-Myers Squibb step up their diabetes-drug partnership.

2 Feb 2013

PKCζ protein plays a critical role in regulating tumor metabolism

Cancer cells need food to survive and grow. They're very good at getting it, too, even when nutrients are scarce. Many scientists have tried killing cancer cells by taking away their favorite food, a sugar called glucose. Unfortunately, this treatment approach not only fails to work, it backfires-glucose-starved tumors actually get more aggressive.

2 Feb 2013

Scientists report first generation of hiPSCs from patients with maturity onset diabetes of the young

Joslin scientists report the first generation of human induced pluripotent stem cells from patients with an uncommon form of diabetes, maturity onset diabetes of the young (MODY). These cells offer a powerful resource for studying the role of genetic factors in the development of MODY and testing potential treatments.

2 Feb 2013

Scientists uncover key mechanism that links obesity and diabetes with cancer

Sugars are needed to provide us with energy and in moderate amounts contribute to our well-being. Sustained high levels of sugars, as is found in diabetics, damages our cells and now is shown that can also increase our chance to get cancer: The dose makes the poison as Paracelsus said.

1 Feb 2013

State highlights: Mayo seeks Minn. help for Rochester expansion; Texas bill on end-of-life treatment offered; Milwaukee County board considers dropping employee coverage

The Mayo Clinic is proposing more than $5 billion in investments in and around Rochester as part of an ambitious expansion plan to create what the clinic calls a "Destination Medical Center." Included in that plan is a request for more than $500 million in state taxpayer money to help fund infrastructure as the Mayo grows. Mayo claims the plan would create between 35,000 and 45,000 new jobs. Mayo is already Minnesota's largest private employer with 32,000 employees in the state.

1 Feb 2013

Obesity becoming serious problem, comparable to cigarette smoking

Dr. Charles H. Hennekens, M.D., Dr.P.H., the first Sir Richard Doll Professor and senior academic advisor to the dean in the Charles E. Schmidt College of Medicine at Florida Atlantic University has published a report in the current issue of the American Journal of Medicine that obesity is becoming as big a hazard worldwide, comparable to cigarette smoking.

1 Feb 2013

Moderate gum disease causes severe infection and inflammation in AIDS animal model

Texas Biomed scientists in San Antonio have found that moderate gum disease in an animal model exposed to an AIDS- like virus had more viral variants causing infection and greater inflammation. Both of these features have potential negative implications in long term disease progression, including other kinds of infections, the researchers say in a new report.

1 Feb 2013

Merck full-year 2012 worldwide sales decrease 2% to $47.3 billion

Merck, known as MSD outside the United States and Canada, today announced financial results for the fourth quarter and full year of 2012.

1 Feb 2013

First Edition: February 1, 2013

Kaiser Health News staff writer Jenny Gold, working in collaboration with NPR, reports: "As of mid-January, most of NYU is up and running again, including the labor and delivery unit. But the question still looms whether NYU will lose some of the patients and even doctors who sought refuge at NYU's biggest competitors after the storm. If that happens, the storm could end up having a long term impact on NYU's valuable share of the fiercely competitive health care market in New York City."

1 Feb 2013

Adults should consume less than 5 g of salt and at least 3,510 mg of potassium per day: WHO

Adults should consume less than 2,000 mg of sodium, or 5 grams of salt, and at least 3,510 mg of potassium per day, according to new guidelines issued by the WHO. A person with either elevated sodium levels and low potassium levels could be at risk of raised blood pressure which increases the risk of heart disease and stroke.

31 Jan 2013

Hypertensive pregnancies need rigorous follow up

Women who have hypertensive complications during pregnancy are at increased risk for developing chronic kidney disease and end-stage renal disease, shows a study in the Canadian Medical Association Journal.

31 Jan 2013

Viscosupplementation may relieve subtalar osteoarthritis

Research suggests that patients with advanced subtalar osteoarthritis may benefit from intra-articular viscosupplementation.

31 Jan 2013

Bispectral index benefits for postoperative recovery unclear

A secondary analysis of two large clinical trials fails to settle the question of whether use of the bispectral index rather than end-tidal anesthetic concentration to monitor general anesthesia results in faster patient recovery.

31 Jan 2013

Strong placebo response key to adolescent migraine trial failures

A strong response to placebo is the main reason drug trials in the treatment of adolescent migraine have so far failed, say researchers.

31 Jan 2013

Dual renin angiotensin system blockade: too many cons

Any benefit of dual blockade of the renin angiotensin system is limited to its effects on surrogate endpoints, and outweighed by an excessive risk for adverse events such as hypotension, hyperkalemia, and renal failure, argue hypertension experts.

31 Jan 2013

Selenium supplements do not reduce risk of developing heart disease according to current evidence

A systematic review published today in The Cochrane Library finds that in well-nourished adults current evidence does not support selenium for preventing heart disease.

31 Jan 2013

World Health Assembly's Executive Board concludes 132nd meeting

"The World Health Assembly's rotating Executive Board meets twice a year, and on 29 January concluded its 132nd meeting with what the WHO director general termed an 'unprecedented' amount of agenda items and documents," Intellectual Property Watch reports.

31 Jan 2013

Finding medical applications for unused inventions: an interview with Gabriel Mecklenburg, Co-Founder of Marblar

Marblar is gamifying the process of technology transfer. We post technology on our platform in the form of a challenge, and the Marblar community then competes to uncover new problems these technologies could solve – thereby discovering new market applications for these technologies.

31 Jan 2013

No added benefit from linagliptin in patients with type 2 diabetes

Linagliptin has been approved since August 2011 to improve blood glucose control in adults with type 2 diabetes. The assessment of the new dossier according to the German Act on the Reform of the Market for Medicinal Products (AMNOG) again showed that no added benefit of the drug over the appropriate comparator therapy (ACT) can be determined, because the pharmaceutical company has not submitted any relevant studies.

31 Jan 2013