Diabetes News and Research

Latest Diabetes News and Research

Results from Medtronic’s Resolute DES clinical study on CAD

According to study results to be featured in Sunday's late-breaking clinical trials session at the American Association of Clinical Endocrinologists (AACE) 21st Annual Scientific and Clinical Congress in Philadelphia, the Resolute drug-eluting stent (DES) from Medtronic, Inc. yields strong performance in coronary artery disease (CAD) patients both with and without diabetes through two years of follow-up.

From Medtronic 28 May 2012

Referral to telephone-based nurse consultation may improve outcomes in women with GDM

Among women with gestational diabetes mellitus, referral to a telephone-based nurse management program was associated with lower risk of high baby birth weight and increased postpartum glucose testing, according to Kaiser Permanente researchers.

28 May 2012

ESRD patients with diabetes may benefit from Baxter’s low-glucose PD regimen

Baxter International Inc. today announced results from two large, international multicenter trials demonstrating that a low glucose peritoneal dialysis (PD) regimen favorably impacted metabolic measures important for end-stage renal disease (ESRD) patients with diabetes, including blood glucose (sugar) control and selected lipids.

From Baxter International Inc. 28 May 2012

Scientists show how hemizygous deletion can contribute to cancer

Chromosomal deletions in DNA often involve just one of two gene copies inherited from either parent. But scientists haven't known how a deletion in one gene from one parent, called a "hemizygous" deletion, can contribute to cancer.

28 May 2012

City of Hope receives CIRM grant to develop T cell-based immunotherapy against glioma

City of Hope was granted a $5,217,004 early translational research award by the California Institute for Regenerative Medicine (CIRM) to support the development of a T cell-based immunotherapy that re-directs a patient's own immune response against glioma stem cells.

28 May 2012

Lilly, Boehringer Ingelheim receive positive opinion from EMA for Jentadueto

Boehringer Ingelheim and Eli Lilly and Company today announced that they have received a positive opinion from the European Medicines Agency's medicinal committee recommending approval of Jentadueto,which combines the DPP-4 inhibitor, linagliptin and metformin in a single tablet. If approved by the European Commission, linagliptin/metformin hydrochloride (HCl) will provide a new, single-tablet treatment option, taken twice-daily, for adults with Type 2 Diabetes who need to improve control of their blood glucose.

28 May 2012

Research roundup: Do mandatory screening laws affect disparities?; Mass. health law, 6 years later

Since Massachusetts passed its own expansive health law, the state's uninsured rate has dropped and access to care has dramatically improved. But as this brief notes, two major issues remain. Massachusetts will have to find ways to contain health care costs -- now under discussion in the state legislature -- as well as align itself with the federal health law. In the process, other states "can draw on some of the state's early successes and challenges"

25 May 2012

Hearing loss linked to several chronic diseases

The Better Hearing Institute (BHI) is raising awareness of the link between hearing loss and some chronic diseases during National Men's Health Week (June 11 – 17).

25 May 2012

Immune system involved in removing Alzheimer's-causing substance in the brain

Recent work in mice suggested that the immune system is involved in removing beta-amyloid, the main Alzheimer's-causing substance in the brain. Researchers have now shown for the first time that this may apply in humans.

25 May 2012

School districts, hospitals cut nurses

Nurses, long a presence in many schools and the backbone of hospital care, are being cut back or stretched thin, according to several news organizations; Meanwhile, NPR reports on a poll that found three out of five patients feel their doctors rush through exams.

25 May 2012

Fever during pregnancy associated with autism or developmental delay

A team of UC Davis researchers has found that mothers who had fevers during their pregnancies were more than twice as likely to have a child with autism or developmental delay than were mothers of typically developing children, and that taking medication to treat fever countered its effect.

25 May 2012

Researchers uncover series of biological events that implicate stem cells' surroundings

Stem cells are essential building blocks for all organisms, from plants to humans. They can divide and renew themselves throughout life, differentiating into the specialized tissues needed during development, as well as cells necessary to repair adult tissue.

25 May 2012

NIH Consortium selects UBM among 11 CoEPEs

With more Americans than ever living with chronic pain, the National Institutes of Health (NIH) Pain Consortium wants the University of Maryland, Baltimore (UMB) and 10 other health professional schools to teach the next generation of health care providers to be better equipped to manage and treat such patients.

25 May 2012

RUB researchers gain new insights into mechanisms of cardiovascular disease

Malformed desmin proteins aggregate with intact proteins of the same kind, thereby triggering skeletal and cardiac muscle diseases, the desminopathies. This was discovered by researchers from the RUB Heart and Diabetes Center NRW in Bad Oeynhausen led by PD Dr. Hendrik Milting in an interdisciplinary research project with colleagues from the universities in Karlsruhe, Würzburg and Bielefeld. They report in the Journal of Biological Chemistry.

25 May 2012

Linagliptin safe and effective for African American patients with type 2 diabetes

Boehringer Ingelheim Pharmaceuticals, Inc. and Eli Lilly and Company today announced Phase 3 study results for linagliptin 5 mg once-daily, which showed significant hemoglobin A1c (HbA1c or A1C) reduction of 0.88 percent compared to 0.24 percent in the placebo group (p=0.0002) at 24 weeks in black or African American adult patients with type 2 diabetes whose blood sugar was not adequately controlled.

25 May 2012

Personality traits may also be part of the longevity genes mix

"It's in their genes" is a common refrain from scientists when asked about factors that allow centenarians to reach age 100 and beyond. Up until now, research has focused on genetic variations that offer a physiological advantage such as high levels of HDL cholesterol. But researchers at Albert Einstein College of Medicine and Ferkauf Graduate School of Psychology of Yeshiva University have found that personality traits like being outgoing, optimistic, easygoing, and enjoying laughter as well as staying engaged in activities may also be part of the longevity genes mix.

25 May 2012

IUDs and implants effectively reduce risk of unintended pregnancy

A study to evaluate birth control methods has found dramatic differences in their effectiveness. Women who used birth control pills, the patch or vaginal ring were 20 times more likely to have an unintended pregnancy than those who used longer-acting forms such as an intrauterine device (IUD) or implant.

24 May 2012

Exposure to toxic flame-retardant chemicals may be higher in underserved children

Environmental health advocates responded to the new Duke University-led study of 83 North Carolina toddlers, published today in Environmental Health Perspectives, suggesting exposure to potentially toxic flame-retardant chemicals may be higher in non-white toddlers than in white toddlers.

24 May 2012

Number of Americans with kidney stones nearly doubled since 1994

The number of Americans suffering from kidney stones between 2007 and 2010 nearly doubled since 1994, according to a study by researchers at the University of California, Los Angeles (UCLA) and RAND.

24 May 2012

New method developed to synthesise a set of potential glycosidase inhibitors

In many biological and pathological processes, glycosidase enzymes attack glycosidic bonds in carbohydrates, glycoproteins, and glycolipids. The ability to modify or block these processes by specific glycosidase inhibitors forms the basis for their potential use in the treatment of viral infections, cancer, and genetic disorders.

24 May 2012